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Review

The Management of Hematopoietic Stem Cell Transplant in People with HIV

by
Jana K. Dickter
1,* and
Courtney Moc Willeford
2
1
Division of Infectious Diseases, Department of Medicine, City of Hope National Medical Center, Duarte, CA 91010, USA
2
Department of Pharmacy Services, City of Hope National Medical Center, Duarte, CA 91010, USA
*
Author to whom correspondence should be addressed.
Viruses 2024, 16(10), 1560; https://doi.org/10.3390/v16101560
Submission received: 17 July 2024 / Revised: 26 September 2024 / Accepted: 27 September 2024 / Published: 30 September 2024

Abstract

Hematopoietic stem cell transplant (HSCT) is now recognized as a standard treatment option for people with HIV (PWH) who develop high-risk hematologic malignancies. However, the involved polypharmacy can lead to complications from drug interactions and toxicities, affecting the efficacy and safety of chemotherapy and antiretroviral therapy (ART). Managing these patients requires a personalized approach, including the careful selection of ART based on previous therapies and potential interactions, alongside risk assessment for infections. This discussion will address the history of HSCT in PWH and management considerations for this group.
Keywords: HIV; hematopoietic stem cell transplant; hematologic malignancy; opportunistic infection HIV; hematopoietic stem cell transplant; hematologic malignancy; opportunistic infection

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MDPI and ACS Style

Dickter, J.K.; Willeford, C.M. The Management of Hematopoietic Stem Cell Transplant in People with HIV. Viruses 2024, 16, 1560. https://doi.org/10.3390/v16101560

AMA Style

Dickter JK, Willeford CM. The Management of Hematopoietic Stem Cell Transplant in People with HIV. Viruses. 2024; 16(10):1560. https://doi.org/10.3390/v16101560

Chicago/Turabian Style

Dickter, Jana K., and Courtney Moc Willeford. 2024. "The Management of Hematopoietic Stem Cell Transplant in People with HIV" Viruses 16, no. 10: 1560. https://doi.org/10.3390/v16101560

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