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Article

Hematologic Complications in Patients Hospitalized with COVID-19 Infection

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75019, USA
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Author to whom correspondence should be addressed.
Hematol. Rep. 2022, 14(3), 228-234; https://doi.org/10.3390/hematolrep14030031
Submission received: 7 May 2022 / Revised: 21 June 2022 / Accepted: 4 July 2022 / Published: 11 July 2022

Abstract

Introduction: This review summarizes data from patients with COVID-19 requiring intensive care unit (ICU) admission. The goals of this study are to showcase some morphological anomalies found in peripheral blood smears from COVID-19 patients and to bring attention to how some hematologic abnormalities in COVID-19 that correspond to disease severity and mortality. Methods: We performed a retrospective analysis of hematologic parameters using peripheral blood smear analysis from 31 COVID-19 patients hospitalized between April 2021 and January 2022. Results: We found abnormal morphology that has not been previously reported. We also report that severe lymphopenia, neutrophilia, acute hemolysis, hematologic malignancies, and increased LDH are associated with ICU admissions, respiratory failure requiring intubation, and poor clinical outcome. Conclusion: We propose these recommendations in the management of COVID-19 patients: 1. Early diagnosis and follow-up of DIC; 2. Optimization of thromboprophylaxis regimen.
Keywords: COVID-19; hematology; complications; hemolysis COVID-19; hematology; complications; hemolysis

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MDPI and ACS Style

Lin, E.; Araj, E.; Markantonis, J.; Luu, H.; Chen, M. Hematologic Complications in Patients Hospitalized with COVID-19 Infection. Hematol. Rep. 2022, 14, 228-234. https://doi.org/10.3390/hematolrep14030031

AMA Style

Lin E, Araj E, Markantonis J, Luu H, Chen M. Hematologic Complications in Patients Hospitalized with COVID-19 Infection. Hematology Reports. 2022; 14(3):228-234. https://doi.org/10.3390/hematolrep14030031

Chicago/Turabian Style

Lin, Elisa, Ellen Araj, John Markantonis, Hung Luu, and Mingyi Chen. 2022. "Hematologic Complications in Patients Hospitalized with COVID-19 Infection" Hematology Reports 14, no. 3: 228-234. https://doi.org/10.3390/hematolrep14030031

APA Style

Lin, E., Araj, E., Markantonis, J., Luu, H., & Chen, M. (2022). Hematologic Complications in Patients Hospitalized with COVID-19 Infection. Hematology Reports, 14(3), 228-234. https://doi.org/10.3390/hematolrep14030031

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