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Case Report

Pneumothorax in an Early Phase after Allogeneic Hematopoietic Stem Cell Transplantation

1
Division of Stem Cell Processing, Center for Stem Cell Biology and Regenerative Medicine, Department of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
2
Division of Stem Cell Processing, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
3
Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
4
Department of Pediatrics, Shinshu Ueda Medical Center, Nagano 386-8610, Japan
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2013, 5(2), e10; https://doi.org/10.4081/hr.2013.e10
Submission received: 30 March 2013 / Revised: 2 May 2013 / Accepted: 21 June 2013 / Published: 28 June 2013

Abstract

Pneumothorax is very rare after early phase of hematopoietic stem cell transplantation (HSCT) and usually accompanied with pulmonary chronic graft-versus-host disease (GVHD), such as bronchiolitis obliterans and bronchiolitis obliterans organizing pneumonia. The present study describes the case of a seventeen-year-old male diagnosed with acute myeloid leukemia who underwent allogeneic bone marrow transplantation (BMT). Pneumothorax occurred at day 43 after BMT. Pneumothorax occurred in early phase of HSCT is extremely rare. The early onset of acute GVHD and the entity of cytomegalovirus might worsen the pulmonary tissue damages for the onset of pneumothorax, indicating that we should be aware of the possibility to occur pneumothorax even in the early period after allogeneic HSCT.
Keywords: pneumothorax; air-leak syndrome; allogeneic hematopoietic stem cell transplantation pneumothorax; air-leak syndrome; allogeneic hematopoietic stem cell transplantation

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MDPI and ACS Style

Ebihara, Y.; Yamamoto, S.; Mochizuki, S.; Tsukada, M.; Taya, Y.; Kawakita, T.; Kato, S.; Ooi, J.; Takahashi, S.; Tojo, A.; et al. Pneumothorax in an Early Phase after Allogeneic Hematopoietic Stem Cell Transplantation. Hematol. Rep. 2013, 5, e10. https://doi.org/10.4081/hr.2013.e10

AMA Style

Ebihara Y, Yamamoto S, Mochizuki S, Tsukada M, Taya Y, Kawakita T, Kato S, Ooi J, Takahashi S, Tojo A, et al. Pneumothorax in an Early Phase after Allogeneic Hematopoietic Stem Cell Transplantation. Hematology Reports. 2013; 5(2):e10. https://doi.org/10.4081/hr.2013.e10

Chicago/Turabian Style

Ebihara, Yasuhiro, Shohei Yamamoto, Shinji Mochizuki, Masao Tsukada, Yuki Taya, Toshiro Kawakita, Seiko Kato, Jun Ooi, Satoshi Takahashi, Arinobu Tojo, and et al. 2013. "Pneumothorax in an Early Phase after Allogeneic Hematopoietic Stem Cell Transplantation" Hematology Reports 5, no. 2: e10. https://doi.org/10.4081/hr.2013.e10

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