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Case Report

Acute Liver Failure in a Pediatric Patient with Congenital Dyserythropoietic Anemia Type I Treated with Deferasirox

1
Pediatric Gastroenterology and Nutrition Unit, Saban Pediatric Medical Center for Israel, Soroka University Medical Center, Beer Sheva 84101, Israel
2
Pediatrics Department B, Saban Pediatric Medical Center for Israel, Soroka University Medical Center, Rager Ave, Beer Sheva 84101, Israel
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2015, 7(3), 5987; https://doi.org/10.4081/hr.2015.5987
Submission received: 5 May 2015 / Revised: 6 September 2015 / Accepted: 7 September 2015 / Published: 23 September 2015

Abstract

Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.
Keywords: congenital dyserythropoietic anemia; deferasirox; acute liver failure; N-acetylcysteine congenital dyserythropoietic anemia; deferasirox; acute liver failure; N-acetylcysteine

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MDPI and ACS Style

Ling, G.; Pinsk, V.; Golan-Tripto, I.; Ling, E. Acute Liver Failure in a Pediatric Patient with Congenital Dyserythropoietic Anemia Type I Treated with Deferasirox. Hematol. Rep. 2015, 7, 5987. https://doi.org/10.4081/hr.2015.5987

AMA Style

Ling G, Pinsk V, Golan-Tripto I, Ling E. Acute Liver Failure in a Pediatric Patient with Congenital Dyserythropoietic Anemia Type I Treated with Deferasirox. Hematology Reports. 2015; 7(3):5987. https://doi.org/10.4081/hr.2015.5987

Chicago/Turabian Style

Ling, Galina, Vered Pinsk, Inbal Golan-Tripto, and Eduard Ling. 2015. "Acute Liver Failure in a Pediatric Patient with Congenital Dyserythropoietic Anemia Type I Treated with Deferasirox" Hematology Reports 7, no. 3: 5987. https://doi.org/10.4081/hr.2015.5987

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