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Article

A Retrospective Study of the Clinical Characteristics and Post-Treatment Hearing Outcome in Idiopathic Sudden Sensorineural Hearing Loss

by
Purushothaman Ganesan
1,*,
Purushothaman Pavanjur Kothandaraman
2,
Simham Swapna
3 and
Vinaya Manchaiah
4,5,6
1
Expert Hearing Solutions, Wall Street Audiology Inc., Saskatoon, Saskatchewan, Canada
2
Department of Otorhinolaryngology, SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India
3
Hindu Mission Hospital, Chennai, Tamil Nadu, India
4
Department of Speech and Hearing Sciences, Lamar University, Beaumont, TX, USA
5
The Swedish Institute for Disability Research, Department of Behavioral Science and Learning, Linköping University, Linköping, Sweden
6
Audiology India, Mysore, Karnataka, India
*
Author to whom correspondence should be addressed.
Audiol. Res. 2017, 7(1), 168; https://doi.org/10.4081/audiores.2017.168
Submission received: 21 December 2016 / Accepted: 2 January 2017 / Published: 15 February 2017

Abstract

The purpose of this retrospective study was to analyze the clinical characteristics and document hearing recovery in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). 122 patients diagnosed with unilateral ISSNHL, from March 2009 to December 2014, were treated with oral steroids and pentoxifylline. Hearing change was evaluated by comparing pre-treatment and post-treatment pure-tone average (PTA) (500, 1K, and 2K Hz), and categorized into complete, partial, and no recovery of hearing. T-test, Wilcoxon Signed Rank test and Regression analysis were employed to analyze the statistical significance. Of the 122 patients, seventy-one (58%) had complete recovery and 34 (28%) had partial recovery. The average pre-treatment PTA was 78.3 ± 16.9 dB whereas post-treatment average was 47.0 ± 20.8 dB, showing statistically significant improvement (t=24.89, P≤0.001). The factors such as presence of tinnitus (P=0.005) and initial milder hearing loss (P=0.005) were found to be significant predictors for hearing recovery. Conventional steroid regimes produced a recovery rate in ISSNHL, which exceeds the spontaneous recovery rate. The current study results highlight the importance of medical treatment in the management of ISSNHL.
Keywords: idiopathic; sudden hearing loss; sensorineural hearing loss; prognosis idiopathic; sudden hearing loss; sensorineural hearing loss; prognosis

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MDPI and ACS Style

Ganesan, P.; Kothandaraman, P.P.; Swapna, S.; Manchaiah, V. A Retrospective Study of the Clinical Characteristics and Post-Treatment Hearing Outcome in Idiopathic Sudden Sensorineural Hearing Loss. Audiol. Res. 2017, 7, 168. https://doi.org/10.4081/audiores.2017.168

AMA Style

Ganesan P, Kothandaraman PP, Swapna S, Manchaiah V. A Retrospective Study of the Clinical Characteristics and Post-Treatment Hearing Outcome in Idiopathic Sudden Sensorineural Hearing Loss. Audiology Research. 2017; 7(1):168. https://doi.org/10.4081/audiores.2017.168

Chicago/Turabian Style

Ganesan, Purushothaman, Purushothaman Pavanjur Kothandaraman, Simham Swapna, and Vinaya Manchaiah. 2017. "A Retrospective Study of the Clinical Characteristics and Post-Treatment Hearing Outcome in Idiopathic Sudden Sensorineural Hearing Loss" Audiology Research 7, no. 1: 168. https://doi.org/10.4081/audiores.2017.168

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