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Article

Iron Chelation Therapy Needed for Serum Ferritin Overloaded Patients of Beta Thalassemia Major

by
Wasim Muhammad
1,*,
Muhammad Ishaq
1,
Muhammad J. Khan
1,
Umair Ahmad
2 and
Muhammad Waseem
3
1
Institute of Paramedical Sciences, Khyber Medical University, Islamabad 19130, Pakistan
2
Department of Medical Lab Technology, University of Haripur, Islamabad, Pakistan
3
Faculty of Rehabilitation and Allied Health Science, Riphah International University, Islamabad, Pakistan
*
Author to whom correspondence should be addressed.
Thalass. Rep. 2021, 11(1), 9779; https://doi.org/10.4081/thal.2021.9779
Submission received: 23 March 2021 / Revised: 23 March 2021 / Accepted: 27 March 2021 / Published: 18 June 2021

Abstract

The main objective of the current study is to evaluate the level and overload of serum ferritin in multi-transfused beta Thalassemia major patients. There is an earnest need to defend the chelation treatment and to make mindfulness about the results of serum ferritin in the patients beta Thalassemia major. This is a Cross sectional analytical study performed in Fatimid foundation Hayatabad, Peshawar, Khyber Pakhtunkhwa province of Pakistan. Those patients who has beta thalassemia major are included in this study. In this study there are total 108 patients in which 54 males and 54 females. The highest mean of serum ferritin level in the category of male was in the age of 12 years were finds 8160.5 ng/mL. Among the female the highest mean of ferritin level was in the age of 17 years were finds 13,349.5 ng/mL. In this study majority of patient’s revealed much high levels of serum ferritin. These levels reveal insufficient chelation. Appropriate chelation of iron load can improve the quality of the life of these patients. The low level of education, Poverty problems, and insufficient health care facility of are the main obstacle in the effective management of ferritin overload in thalassemia patients.
Keywords: serum ferritin level; iron overload; iron chelation; beta thalassemia major serum ferritin level; iron overload; iron chelation; beta thalassemia major

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MDPI and ACS Style

Muhammad, W.; Ishaq, M.; Khan, M.J.; Ahmad, U.; Waseem, M. Iron Chelation Therapy Needed for Serum Ferritin Overloaded Patients of Beta Thalassemia Major. Thalass. Rep. 2021, 11, 9779. https://doi.org/10.4081/thal.2021.9779

AMA Style

Muhammad W, Ishaq M, Khan MJ, Ahmad U, Waseem M. Iron Chelation Therapy Needed for Serum Ferritin Overloaded Patients of Beta Thalassemia Major. Thalassemia Reports. 2021; 11(1):9779. https://doi.org/10.4081/thal.2021.9779

Chicago/Turabian Style

Muhammad, Wasim, Muhammad Ishaq, Muhammad J. Khan, Umair Ahmad, and Muhammad Waseem. 2021. "Iron Chelation Therapy Needed for Serum Ferritin Overloaded Patients of Beta Thalassemia Major" Thalassemia Reports 11, no. 1: 9779. https://doi.org/10.4081/thal.2021.9779

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