Treatment in Patients with Psoriatic Disease and Rheumatoid Arthritis: Seven Case Reports
Round 1
Reviewer 1 Report
Comments to the Authors of Manuscript Number clinpract-2150707
with full title
Treatment strategy in patients with psoriatic disease and rheumatoid arthritis
11. In the abstract (line 7) and in line 244: I suggest changing the word “dermatitis” with: inflammatory skin disease.
2. It is necessary to describe the psoriatic rash in each case, it is not ok to generalize the lesions as psoriatic rash. Also, describe the nail psoriasis lesions for each patient that has nail lesions.
3. Detail the dose and periods of time of MTX, Prednisolone, Cyclosporine and other treatments used in all the cases. Please include the histopathological exam from the skin that confirms the psoriasis diagnosis and PASI before the administration of biological agent.
Author Response
Responses to the comments of Reviewer #1
Comments to the Author:
- In the abstract (line 7) and in line 244: I suggest changing the word “dermatitis” with: inflammatory skin disease.
Response: Thank you for your suggestions. We have changed the text as the reviewer pointed out for line 7. As for line 244, we have revised the text since these clear data are proven events at the experimental level in mice.
- It is necessary to describe the psoriatic rash in each case, it is not ok to generalize the lesions as psoriatic rash. Also, describe the nail psoriasis lesions for each patient that has nail lesions.
Response: Thank you for your pointing this out. We have added descriptions of skin and nail lesions in each case.
- Detail the dose and periods of time of MTX, Prednisolone, Cyclosporine and other treatments used in all the cases. Please include the histopathological exam from the skin that confirms the psoriasis diagnosis and PASI before the administration of biological agent.
Response: Thank you for your valuable input. We have added the dosage and duration of each drug as far as we can check. We have also added PASI score. Pathological tests have not been performed or performed by a previous physician, and no documents are available.
Reviewer 2 Report
Reviewer comments
Journal clinics and practice
Title Treatment strategy in patients with psoriatic disease and rheumatoid arthritis
This manuscript covers an important topic which is the overlap between RA and PsA. Indeed, this is an interesting topic .Some points need to be addressed
The title gives an impression of a review article. However, the research style is case report .So ,the authors should refer to the study design in the title
24.. Because it is not a rare disease, we encounter both PsA and 24 RA cases.
This sentence is difficult to be understood
Introduction ...There are many sentences in the introduction that have no refences
238.. RA is seropositive, and the underlying pathology is arthropathy... a difficult sentence to be understood
242.. expectancy…
A reference is needed here
244.. dermatitis
Psoriasis instead of dermatitis
244.. The diagnosis and treatment of comorbidity has been recently discussed
What is meant by the word “comorbidity”
245… One such complication is enthesitis.
246.. leading to 246 synovitis secondary
English editing and grammar revision are mandatory
250.. RA,
The author started with RA first then PsA, then again RA …
The writing manner should be more concise and scientific
255.. Neither PsA nor
The author started by treatment then clinical manifestations. The writing of discussion should be rearranged again
The strength, limitations and recommendations of the study should be added at the end of the discussion section
Author Response
Responses to the comments of Reviewer #1
Comments to the Author:
This manuscript covers an important topic which is the overlap between RA and PsA. Indeed, this is an interesting topic. Some points need to be addressed
The title gives an impression of a review article. However, the research style is case report .So ,the authors should refer to the study design in the title
Response: Thank you for your suggestions. We have changed the title.
24.. Because it is not a rare disease, we encounter both PsA and 24 RA cases.
This sentence is difficult to be understood
Response: Thank you for pointing it out. We have changed the sentence.
Introduction ...There are many sentences in the introduction that have no refences
Response: Thank you for pointing it out. We have added the references.
238.. RA is seropositive, and the underlying pathology is arthropathy... a difficult sentence to be understood
Response: Thank you for your suggestion. We have changed the sentence.
242.. expectancy…
A reference is needed here
Response: Thank you for pointing it out. We have added the references.
244.. dermatitis
Psoriasis instead of dermatitis
Response: Since these clear data are proven events at the experimental level in mice, we have revised the text.
244.. The diagnosis and treatment of comorbidity has been recently discussed
What is meant by the word “comorbidity”
Response: Thank you for pointing it out. We have added more details about comorbidity.
245… One such complication is enthesitis.
246.. leading to 246 synovitis secondary
English editing and grammar revision are mandatory
Response: Thank you for your suggestions. A native English-speaking scientist proofread it. A certificate is also attached.
250.. RA,
The author started with RA first then PsA, then again RA …
The writing manner should be more concise and scientific
Response: Thank you for pointing it out. We have corrected the text according to your point.
255.. Neither PsA nor
The author started by treatment then clinical manifestations. The writing of discussion should be rearranged again
The strength, limitations and recommendations of the study should be added at the end of the discussion section
Response: Thank you for pointing it out. We have totally arranged the discussion section.
Round 2
Reviewer 1 Report
Please verify the bibliography.
In the last manuscript appear 2 different bibliography. Please correct this aspect.
Author Response
Responses to the comments of Reviewer #1
Comments to the Author:
- Please verify the bibliography.
In the last manuscript appear 2 different bibliography. Please correct this aspect.
Response: Apologies for the careless mistake. The duplicate reference has been removed.
Reviewer 2 Report
The manuscript has improved to a great extent
Author Response
Thank you for taking care of our manuscript.
