Prospective Comparison of Short-Term Outcomes in Kinematic and Mechanical Alignment Total Knee Arthroplasty
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Patient Selection
Data Collection
2.2. Variable Definitions
2.3. Surgical and Rehabilitation Techniques
2.4. Statistical Analysis
3. Results
3.1. Hospitalization and POD 1 Outcomes
3.2. POD 14 Outcomes
3.3. Sensitivity Analysis of Loss to Follow-Up
4. Discussion
4.1. Limitations
4.2. Strengths
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | Kinematic TKA (N = 77) | Mechanical TKA (N = 26) | p-Value |
---|---|---|---|
Age, years (mean ± SD) | 68.0 ± 8.6 | 71.0 ± 7.6 | 0.312 |
Sex, female (%) | 62.3 | 65.4 | 0.781 |
BMI, kg/m2 (mean ± SD) | 31.8 ± 6.8 | 31.5 ± 5.4 | 0.835 |
Side operated, Left (%) | 45.0 | 63.6 | 0.135 |
Implant design, Cruciate Retaining (%) | 84.4 | 80.8 | 0.665 |
Smoker (%) | 11.7 | 11.5 | 0.984 |
ASA (%) | 0.944 | ||
1 | 3.0 | 4.5 | |
2 | 48.5 | 45.5 | |
3 | 48.5 | 50.0 | |
CCI (%) | 0.652 | ||
No or mild | 32.4 | 22.7 | |
Moderate | 55.9 | 68.2 | |
Severe | 11.8 | 9.1 | |
Preoperative VAS (mean ± SD) | 8.3 ± 1.4 | 8.5 ± 1.2 | 0.673 |
Preoperative TUG, seconds (mean ± SD) | 19.5 ± 9.4 | 23.7 ± 10.6 | 0.064 |
Preoperative Stairs climb, seconds (mean ± SD) | 29.9 ± 21.4 | 46.0 ± 23.7 | 0.003 |
Preoperative OKS (mean ± SD) | 16.4 ± 7.7 | 14.9 ± 7.2 | 0.436 |
Preoperative SF 12 (mean ± SD) | |||
PCS | 27.9 ± 7.8 | 27.6 ± 6.4 | 0.973 |
MCS | 47.0 ± 12.6 | 43.0 ± 9.0 | 0.129 |
Preoperative KOOS (mean ± SD) | |||
Overall | 31.3 ± 12.9 | 26.1 ± 11.2 | 0.068 |
Symptoms | 47.0 ± 12.6 | 43.0 ± 9.1 | 0.077 |
Pain | 36.8 ± 18.8 | 31.5 ± 15.4 | 0.194 |
Function | 38.2 ± 18.2 | 31.2 ± 14.4 | 0.103 |
Quality of Life | 17.8 ± 14.0 | 15.3 ± 13.3 | 0.553 |
Sports | 15.7 ± 19.5 | 11.7 ± 19.4 | 0.229 |
Preoperative FJS (mean ± SD) | 9.5 ± 7.9 | 9.2 ± 5.6 | 0.088 |
Variable | Kinematic TKA (N = 54) | Mechanical TKA (N = 23) | p-Value |
---|---|---|---|
Hospitalization | |||
Hospitalization duration, days (mean ± SD) | 2.8 ± 1.4 | 3.6 ± 1.4 | 0.013 |
Discharge to home (%) | 75.0 | 36.4 | 0.001 |
Total opioid use (Morphine Equivalent Dose) (mean ± SD) | 58.9 ± 47.5 | 78.7 ± 67.3 | 0.224 |
POD 1 | |||
TUG, seconds (mean ± SD) | 28.2 ± 26.8 | 47.6 ± 42.6 | 0.023 |
VAS (mean ± SD) | 5.9 ± 4.1 | 5.8 ± 4.1 | 0.970 |
POD 14 | |||
TUG, seconds (mean ± SD) | 22.7 ± 20.2 | 20.7 ± 19.8 | 0.774 |
Stairs test, seconds (mean ± SD) | 55.3 ± 60.1 | 52.6 ± 77.7 | 0.680 |
VAS (mean ± SD) | 5.9 ± 3.2 | 4.7 ± 3.8 | 0.192 |
OKS (mean ± SD) | 14.2 ± 9.9 | 9.4 ± 10.5 | 0.034 |
SF 12 MCS (mean ± SD) | 40.1 ± 19.2 | 22.1 ± 18.0 | <0.001 |
KOOS Symptoms (mean ± SD) | 42.6 ± 25.3 | 28.7 ± 26.6 | 0.033 |
KOOS Function and Daily Living (mean ± SD) | 35.4 ± 24.6 | 25.5 ± 25.1 | 0.093 |
Return to ER due to pain (%) | 4.2 | 18.2 | 0.052 |
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Vinograd, O.; Essa, A.; Steinberg, N.; Mitchnik, I.Y.; Avraham, D.; Rotem, I.; Vinograd, A.; Beer, Y.; Shohat, N.; Bar-Ziv, Y. Prospective Comparison of Short-Term Outcomes in Kinematic and Mechanical Alignment Total Knee Arthroplasty. Clin. Pract. 2025, 15, 162. https://doi.org/10.3390/clinpract15090162
Vinograd O, Essa A, Steinberg N, Mitchnik IY, Avraham D, Rotem I, Vinograd A, Beer Y, Shohat N, Bar-Ziv Y. Prospective Comparison of Short-Term Outcomes in Kinematic and Mechanical Alignment Total Knee Arthroplasty. Clinics and Practice. 2025; 15(9):162. https://doi.org/10.3390/clinpract15090162
Chicago/Turabian StyleVinograd, Ofir, Ahmad Essa, Netanel Steinberg, Ilan Y. Mitchnik, Dana Avraham, Inon Rotem, Adi Vinograd, Yiftah Beer, Noam Shohat, and Yaron Bar-Ziv. 2025. "Prospective Comparison of Short-Term Outcomes in Kinematic and Mechanical Alignment Total Knee Arthroplasty" Clinics and Practice 15, no. 9: 162. https://doi.org/10.3390/clinpract15090162
APA StyleVinograd, O., Essa, A., Steinberg, N., Mitchnik, I. Y., Avraham, D., Rotem, I., Vinograd, A., Beer, Y., Shohat, N., & Bar-Ziv, Y. (2025). Prospective Comparison of Short-Term Outcomes in Kinematic and Mechanical Alignment Total Knee Arthroplasty. Clinics and Practice, 15(9), 162. https://doi.org/10.3390/clinpract15090162