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Clinics and Practice
Volume 2
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10.4081/cp.2012.e68
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Asymptomatic T-Cell Large Granular Lymphocyte Leukemia with an Unusual Immunophenotype

by
Panagiota K. Petsa
1,
Achilleas Karamoutsios
1,
Lefkothea Dova
1,
Leonidas Benetatos
1,
Asimina Petsiou
1,
Nikolaos Kolaitis
1,
Antonis Georgopoulos
1 and
Georgios Vartholomatos
1,*
1
Laboratory of Hematology, Unit of Molecular Biology, University Hospital of Ioannina, Corfu, Greece
2
Laboratory of Hematology, University Hospital of Ioannina, Corfu, Greece
3
General Hospital of Corfu, Laboratory of Hematology, Corfu, Greece
*
Author to whom correspondence should be addressed.
Clin. Pract. 2012, 2(3), e68; https://doi.org/10.4081/cp.2012.e68
Submission received: 21 October 2011 / Revised: 29 May 2011 / Accepted: 7 June 2011 / Published: 27 June 2012

Abstract

T-cell large granular lymphocyte (T-LGL) leukemia represents a clonal proliferation of cytotoxic T-cells which etiology has not been entirely elucidated. However, CD4+, CD4–,CD8–, CD4+, CD8+ cases have been described. The disease is usually characterized by cytopenias and a modest lymphocytosis. The majority of patients with T-LGL leukemia remains asymptomatic for a long period and will require treatment later during the course of their disease. Hereby we describe a case of T-LGL leukemia diagnosed by flow cytometry, which presented indolent course and required no treatment so far.
Keywords: large granular lymphocytes; T-LGL leukemia; T cell receptor; flow cytometry large granular lymphocytes; T-LGL leukemia; T cell receptor; flow cytometry

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MDPI and ACS Style

Petsa, P.K.; Karamoutsios, A.; Dova, L.; Benetatos, L.; Petsiou, A.; Kolaitis, N.; Georgopoulos, A.; Vartholomatos, G. Asymptomatic T-Cell Large Granular Lymphocyte Leukemia with an Unusual Immunophenotype. Clin. Pract. 2012, 2, e68. https://doi.org/10.4081/cp.2012.e68

AMA Style

Petsa PK, Karamoutsios A, Dova L, Benetatos L, Petsiou A, Kolaitis N, Georgopoulos A, Vartholomatos G. Asymptomatic T-Cell Large Granular Lymphocyte Leukemia with an Unusual Immunophenotype. Clinics and Practice. 2012; 2(3):e68. https://doi.org/10.4081/cp.2012.e68

Chicago/Turabian Style

Petsa, Panagiota K., Achilleas Karamoutsios, Lefkothea Dova, Leonidas Benetatos, Asimina Petsiou, Nikolaos Kolaitis, Antonis Georgopoulos, and Georgios Vartholomatos. 2012. "Asymptomatic T-Cell Large Granular Lymphocyte Leukemia with an Unusual Immunophenotype" Clinics and Practice 2, no. 3: e68. https://doi.org/10.4081/cp.2012.e68

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