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Clinics and Practice
Volume 9
Issue 4
10.4081/cp.2019.1184
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Severe Nephritis as Initial Sign of Waldenström’s Macroglobulinemia

by
Thomas Knoop
1,2,
Kristin Kampevold Larsen
3,
Friedemann Leh
3,
Anette Lodvir Hemsing
1,
Ingrid Anna Teigen
4 and
Håkon Reikvam
1,5,*
1
Department of Medicine, Haukeland University Hospital, Bergen, Norway
2
Institute of Medical Science, University of Bergen, Bergen, Norway
3
Department of Pathology, Haukeland University Hospital, Bergen, Norway
4
Department of Pharmacology, Haukeland University Hospital, Bergen, Norway
5
Institute of Clinical Science, University of Bergen, Bergen, Norway
*
Author to whom correspondence should be addressed.
Clin. Pract. 2019, 9(4), 1184; https://doi.org/10.4081/cp.2019.1184
Submission received: 9 July 2019 / Revised: 7 November 2019 / Accepted: 11 November 2019 / Published: 19 December 2019

Abstract

Waldenström’s macroglobulinemia (WM), characterized with monoclonal immunoglobulins of type M and lymphoplasmacytic lymphoma, is a rare clonal Bcell disorder. WM usually present as an indolent lymphoma, and renal involvement is, in contrast to multiple myeloma, very rarely seen. We present a patient presenting with severe nephritis and nephrotic range proteinuria of more than 9 g/day as initial manifestations of WM. Furthermore, we discuss diagnostic and therapeutic approaches for this rare manifestation of the disease, in the light of recent research and treatment recommendations.
Keywords: nephrite; hypertension; proteinuria; Waldenström’s macroglobulinemia nephrite; hypertension; proteinuria; Waldenström’s macroglobulinemia

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MDPI and ACS Style

Knoop, T.; Larsen, K.K.; Leh, F.; Hemsing, A.L.; Teigen, I.A.; Reikvam, H. Severe Nephritis as Initial Sign of Waldenström’s Macroglobulinemia. Clin. Pract. 2019, 9, 1184. https://doi.org/10.4081/cp.2019.1184

AMA Style

Knoop T, Larsen KK, Leh F, Hemsing AL, Teigen IA, Reikvam H. Severe Nephritis as Initial Sign of Waldenström’s Macroglobulinemia. Clinics and Practice. 2019; 9(4):1184. https://doi.org/10.4081/cp.2019.1184

Chicago/Turabian Style

Knoop, Thomas, Kristin Kampevold Larsen, Friedemann Leh, Anette Lodvir Hemsing, Ingrid Anna Teigen, and Håkon Reikvam. 2019. "Severe Nephritis as Initial Sign of Waldenström’s Macroglobulinemia" Clinics and Practice 9, no. 4: 1184. https://doi.org/10.4081/cp.2019.1184

APA Style

Knoop, T., Larsen, K. K., Leh, F., Hemsing, A. L., Teigen, I. A., & Reikvam, H. (2019). Severe Nephritis as Initial Sign of Waldenström’s Macroglobulinemia. Clinics and Practice, 9(4), 1184. https://doi.org/10.4081/cp.2019.1184

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