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Residual Kidney Function in Hemodialysis: Its Importance and Contribution to Improved Patient Outcomes
by
Yoshitsugu Obi
Yoshitsugu Obi 1,*
,
Jochen G. Raimann
Jochen G. Raimann 2,3
,
Kamyar Kalantar-Zadeh
Kamyar Kalantar-Zadeh 4,5,6
and
Mariana Murea
Mariana Murea 7,*
1
Division of Nephrology, Department of Medicine, The University of Mississippi Medical Center, Jackson, MS 39216, USA
2
Renal Research Institute, New York, NY 10065, USA
3
Katz School of Science and Health at Yeshiva University, New York, NY 10033, USA
4
Tibor Rubin Veterans Affairs Long Beach Healthcare System, Long Beach, CA 90822, USA
5
The Lundquist Institute at Harbor, UCLA Medical Center, Torrance, CA 90502, USA
6
Division of Nephrology, Hypertension, and Kidney Transplantation, University of California Irvine, Orange, CA 92868, USA
7
Department of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA
*
Authors to whom correspondence should be addressed.
Toxins 2024, 16(7), 298; https://doi.org/10.3390/toxins16070298 (registering DOI)
Submission received: 30 April 2024
/
Revised: 27 May 2024
/
Accepted: 11 June 2024
/
Published: 28 June 2024
Abstract
Individuals afflicted with advanced kidney dysfunction who require dialysis for medical management exhibit different degrees of native kidney function, called residual kidney function (RKF), ranging from nil to appreciable levels. The primary focus of this manuscript is to delve into the concept of RKF, a pivotal yet under-represented topic in nephrology. To begin, we unpack the definition and intrinsic nature of RKF. We then juxtapose the efficiency of RKF against that of hemodialysis in preserving homeostatic equilibrium and facilitating physiological functions. Given the complex interplay of RKF and overall patient health, we shed light on the extent of its influence on patient outcomes, particularly in those living with advanced kidney dysfunction and on dialysis. This manuscript subsequently presents methodologies and measures to assess RKF, concluding with the potential benefits of targeted interventions aimed at preserving RKF.
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MDPI and ACS Style
Obi, Y.; Raimann, J.G.; Kalantar-Zadeh, K.; Murea, M.
Residual Kidney Function in Hemodialysis: Its Importance and Contribution to Improved Patient Outcomes. Toxins 2024, 16, 298.
https://doi.org/10.3390/toxins16070298
AMA Style
Obi Y, Raimann JG, Kalantar-Zadeh K, Murea M.
Residual Kidney Function in Hemodialysis: Its Importance and Contribution to Improved Patient Outcomes. Toxins. 2024; 16(7):298.
https://doi.org/10.3390/toxins16070298
Chicago/Turabian Style
Obi, Yoshitsugu, Jochen G. Raimann, Kamyar Kalantar-Zadeh, and Mariana Murea.
2024. "Residual Kidney Function in Hemodialysis: Its Importance and Contribution to Improved Patient Outcomes" Toxins 16, no. 7: 298.
https://doi.org/10.3390/toxins16070298
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