Fabrication of Microspheres from High-Viscosity Bioink Using a Novel Microfluidic-Based 3D Bioprinting Nozzle
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Microfluidic Chip Setup
2.3. Preparation of Microspheres
2.4. Drug Loading and Controlled Release
3. Results and Discussions
3.1. Effect of Flow Rates on Flowing Condition
3.2. Control of the Size of Microspheres
3.3. Structures of Microspheres
3.4. Application in Controlled-Drug-Release
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Zhang, S.; Li, G.; Man, J.; Zhang, S.; Li, J.; Li, J.; Li, D. Fabrication of Microspheres from High-Viscosity Bioink Using a Novel Microfluidic-Based 3D Bioprinting Nozzle. Micromachines 2020, 11, 681. https://doi.org/10.3390/mi11070681
Zhang S, Li G, Man J, Zhang S, Li J, Li J, Li D. Fabrication of Microspheres from High-Viscosity Bioink Using a Novel Microfluidic-Based 3D Bioprinting Nozzle. Micromachines. 2020; 11(7):681. https://doi.org/10.3390/mi11070681
Chicago/Turabian StyleZhang, Shanguo, Guiling Li, Jia Man, Song Zhang, Jianyong Li, Jianfeng Li, and Donghai Li. 2020. "Fabrication of Microspheres from High-Viscosity Bioink Using a Novel Microfluidic-Based 3D Bioprinting Nozzle" Micromachines 11, no. 7: 681. https://doi.org/10.3390/mi11070681