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Article

Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters

by
Celia Sanchez-Ramos
1,
Cristina Bonnin-Arias
1,
Vanesa Blázquez-Sánchez
1,
Victoria Aguirre-Vilacoro
1,
Teresa Cobo
2,
Olivia García-Suarez
3,
María Jesús Perez-Carrasco
4,
Cristina Alvarez-Peregrina
5,* and
José A. Vega
3,6
1
Grupo de Neuro-Computación y Neuro-Robótica, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, Spain
2
Departamento de Cirugía y Especialidades Médico-Quirúrgicas, Universidad de Oviedo, 33006 Oviedo, Spain
3
Grupo SINPOS, Departamento de Morfología y Biología Celular, Universidad de Oviedo, 33006 Oviedo, Spain
4
Departamento de Óptica II: Optometría y Visión, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, Spain
5
Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain
6
Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago 7500912, Chile
*
Author to whom correspondence should be addressed.
Cells 2021, 10(11), 3248; https://doi.org/10.3390/cells10113248
Submission received: 29 September 2021 / Revised: 15 November 2021 / Accepted: 16 November 2021 / Published: 19 November 2021
(This article belongs to the Special Issue The Retina in Health and Disease)
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Abstract

(1) Background: Ocular exposure to intense light or long-time exposure to low-intensity short-wavelength lights may cause eye injury. Excessive levels of blue light induce photochemical damage to the retinal pigment and degeneration of photoreceptors of the outer segments. Currently, people spend a lot of time watching LED screens that emit high proportions of blue light. This study aims to assess the effects of light emitted by LED tablet screens on pigmented rat retinas with and without optical filters. (2) Methods: Commercially available tablets were used for exposure experiments on three groups of rats. One was exposed to tablet screens, the other was exposed to the tablet screens with a selective filter and the other was a control group. Structure, gene expression (including life/death, extracellular matrix degradation, growth factors, and oxidative stress related genes), and immunohistochemistry in the retina were compared among groups. (3) Results: There was a reduction of the thickness of the external nuclear layer and changes in the genes involved in cell survival and death, extracellular matrix turnover, growth factors, inflammation, and oxidative stress, leading decrease in cell density and retinal damage in the first group. Modulation of gene changes was observed when the LED light of screens was modified with an optical filter. (4) Conclusions: The use of short-wavelength selective filters on the screens contribute to reduce LED light-induced damage in the rat retina.
Keywords: retinal light injury; LED screen; optical filter; retinal protection retinal light injury; LED screen; optical filter; retinal protection

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MDPI and ACS Style

Sanchez-Ramos, C.; Bonnin-Arias, C.; Blázquez-Sánchez, V.; Aguirre-Vilacoro, V.; Cobo, T.; García-Suarez, O.; Perez-Carrasco, M.J.; Alvarez-Peregrina, C.; Vega, J.A. Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters. Cells 2021, 10, 3248. https://doi.org/10.3390/cells10113248

AMA Style

Sanchez-Ramos C, Bonnin-Arias C, Blázquez-Sánchez V, Aguirre-Vilacoro V, Cobo T, García-Suarez O, Perez-Carrasco MJ, Alvarez-Peregrina C, Vega JA. Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters. Cells. 2021; 10(11):3248. https://doi.org/10.3390/cells10113248

Chicago/Turabian Style

Sanchez-Ramos, Celia, Cristina Bonnin-Arias, Vanesa Blázquez-Sánchez, Victoria Aguirre-Vilacoro, Teresa Cobo, Olivia García-Suarez, María Jesús Perez-Carrasco, Cristina Alvarez-Peregrina, and José A. Vega. 2021. "Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters" Cells 10, no. 11: 3248. https://doi.org/10.3390/cells10113248

APA Style

Sanchez-Ramos, C., Bonnin-Arias, C., Blázquez-Sánchez, V., Aguirre-Vilacoro, V., Cobo, T., García-Suarez, O., Perez-Carrasco, M. J., Alvarez-Peregrina, C., & Vega, J. A. (2021). Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters. Cells, 10(11), 3248. https://doi.org/10.3390/cells10113248

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