HO-1 and Heme: G-Quadruplex Interaction Choreograph DNA Damage Responses and Cancer Growth
Abstract
:1. Introduction
2. Role of Heme Metabolism and Nuclear HO-1 in Gene Expression Control
3. Heme and G4 Interaction: Resolution by Helicases
4. Heme Metabolism and Control of DNA Damage-Associated with G-Quadruplexes
4.1. Heme:G4 as Therapeutic Targets in Cancer
4.2. Discussion and Future Directions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Canesin, G.; Muralidharan, A.M.; Swanson, K.D.; Wegiel, B. HO-1 and Heme: G-Quadruplex Interaction Choreograph DNA Damage Responses and Cancer Growth. Cells 2021, 10, 1801. https://doi.org/10.3390/cells10071801
Canesin G, Muralidharan AM, Swanson KD, Wegiel B. HO-1 and Heme: G-Quadruplex Interaction Choreograph DNA Damage Responses and Cancer Growth. Cells. 2021; 10(7):1801. https://doi.org/10.3390/cells10071801
Chicago/Turabian StyleCanesin, Giacomo, Anindhita Meena Muralidharan, Kenneth D. Swanson, and Barbara Wegiel. 2021. "HO-1 and Heme: G-Quadruplex Interaction Choreograph DNA Damage Responses and Cancer Growth" Cells 10, no. 7: 1801. https://doi.org/10.3390/cells10071801