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Review
Peer-Review Record

The Ehlers–Danlos Syndromes against the Backdrop of Inborn Errors of Metabolism

by Tim Van Damme, Marlies Colman, Delfien Syx and Fransiska Malfait *
Reviewer 1:
Reviewer 2: Anonymous
Submission received: 10 January 2022 / Accepted: 26 January 2022 / Published: 29 January 2022
(This article belongs to the Special Issue Genetic Research in Metabolic Diseases)

Round 1

Reviewer 1 Report

It was a pleasure to review this very well written and comprehensive review article about Ehlers-Danlos syndrome and an interesting parallel with a subset of inborn errors of metabolism disorders. The structure of the article reflects the clinical, histological and molecular aspects of EDS, with up-to-date experimental evidence and highlighting the unknown elements. This will be of great interest to both clinicians and researchers.

Reviewer 2 Report

Van Damme et al presents a very comprehensive overview of Ehlers-Danlos syndrome, including clinical, genetic and molecular findings.

The review is very well-written, tables are useful also in a clinical setting.

I could wish for a few closing remarks at the end of the paper, but otherwise I have no commonts.

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