Changes in the Diversity of Human Skin Microbiota to Cosmetic Serum Containing Prebiotics: Results from a Randomized Controlled Trial
Abstract
:1. Introduction
2. Materials and Methods
2.1. Cosmetic Serum Formulation
2.2. Subjects and Sampling
2.3. Skin Assessments
2.4. DNA Extraction, Amplification, and Sequencing
2.5. Bioinformatic Analysis Using 16S rRNA Sequences
2.6. Statistical Analysis
3. Results
3.1. Changes in the Water Holding Capacity of the Skin Surface and TEWL by Prebiotics-Containing Cosmetic Serum Treatment
3.2. Changes in Skin Pigments by Prebiotics-Containing Cosmetic Serum Treatment
3.3. Changes in the Skin Wrinkles Using Replica by Prebiotics-Containing Cosmetic Serum Treatment
3.4. Changes in the Water Holding Capacity of the Skin Surface and TEWL by Prebiotics-Containing Cosmetic Serum Treatment
3.5. Microbial Diversity Within and between the Groups
3.6. Correlation Analyses between Skin Microbiota and Skin Parameters
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Hong, K.-B.; Hong, Y.H.; Jung, E.Y.; Jo, K.; Suh, H.J. Changes in the Diversity of Human Skin Microbiota to Cosmetic Serum Containing Prebiotics: Results from a Randomized Controlled Trial. J. Pers. Med. 2020, 10, 91. https://doi.org/10.3390/jpm10030091
Hong K-B, Hong YH, Jung EY, Jo K, Suh HJ. Changes in the Diversity of Human Skin Microbiota to Cosmetic Serum Containing Prebiotics: Results from a Randomized Controlled Trial. Journal of Personalized Medicine. 2020; 10(3):91. https://doi.org/10.3390/jpm10030091
Chicago/Turabian StyleHong, Ki-Bae, Yang Hee Hong, Eun Young Jung, Kyungae Jo, and Hyung Joo Suh. 2020. "Changes in the Diversity of Human Skin Microbiota to Cosmetic Serum Containing Prebiotics: Results from a Randomized Controlled Trial" Journal of Personalized Medicine 10, no. 3: 91. https://doi.org/10.3390/jpm10030091