Atlas of PD-L1 for Pathologists: Indications, Scores, Diagnostic Platforms and Reporting Systems
Round 1
Reviewer 1 Report
This review article briefly summarized the current status of PD-L1 as a biomarker for immune checkpoint inhibitor treatment. The review provides useful information on various scoring systems and diagnostic platforms for PD-L1 expression that will be a common interest for oncologists and pathologists. The authors have focused on several solid cancers but including discussions on hematological malignancies would improve readership.
Author Response
Please see the attachment.
Author Response File: Author Response.doc
Reviewer 2 Report
This manuscript by Marletta et al. summarizes the evidence on the application of the PD-L1 test in the situations most frequently requested by the pathologist, characterizing currently recommended indications, diagnostic platforms and scoring systems. I recommend a minor revision.
1. The "INTRODUCTION" section should be enriched.
2. I suggest authors to add a representative figure in each subsection in the manuscript.
3. Authors should provide their own perspectives in "CONCLUSIONS AND PERSPECTIVES" section.
Author Response
Please see the attachment.
Author Response File: Author Response.doc