Next Article in Journal
Neck Circumference Cut-Off Points for Identifying Adiposity: Association with Chronic Metabolic Diseases in Older People
Previous Article in Journal
Comparison of a Two (32/38 Weeks) versus One (36 Weeks) Ultrasound Protocol for the Detection of Decreased Fetal Growth and Adverse Perinatal Outcome
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JPM
Volume 14
Issue 7
10.3390/jpm14070711
jpm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Study Protocol

Empowerment, Pain Control, and Quality of Life Improvement in Early Triple-Negative Breast Cancer Patients through Pain Neuroscience Education: A Prospective Cohort Pilot Study Protocol (EMPOWER Trial)

by
Paola Tiberio
1,
Marco Balordi
2,
Matteo Castaldo
2,3,4,
Alessandro Viganò
5,
Flavia Jacobs
1,2,
Chiara Benvenuti
1,2,
Rosalba Torrisi
1,
Alberto Zambelli
1,2,
Armando Santoro
1,2 and
Rita De Sanctis
1,2,*
1
Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, 20089 Milan, Italy
2
Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy
3
Department of Health Science and Technology, Center for Pain and Neuroplasticity (CNAP), School of Medicine, Sensory Motor Interaction (SMI), Aalborg University, 9220 Aalborg, Denmark
4
Clinical Psychology, Clinical Psychophysiology and Clinical Neuropsychology Labs, Parma University, 43126 Parma, Italy
5
IRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, Italy
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2024, 14(7), 711; https://doi.org/10.3390/jpm14070711
Submission received: 30 May 2024 / Revised: 24 June 2024 / Accepted: 26 June 2024 / Published: 1 July 2024
(This article belongs to the Section Disease Biomarker)
Versions Notes

Abstract

The treatment of early triple-negative breast cancer (eTNBC) has improved patients’ prognosis but often leads to adverse events and sequelae affecting quality of life (QoL). Pain Neuroscience Education (PNE) is a promising non-pharmacological intervention in this field. Preliminary data have shown the beneficial effect of PNE in BC survivors. However, there are still gaps in knowledge regarding its optimal use in eTNBC. To address this issue, a prospective pilot study will enroll 30 consecutive patients diagnosed with eTNBC at IRCCS Humanitas Research Hospital. The PNE program will consist of 10 weekly sessions to be started within 4 weeks of the onset or worsening of a pain syndrome (PS). QoL, pain, and disability will be assessed before, during, at the end of, and 6 months after PNE using validated questionnaires. Peripheral venous blood samples will be taken before and at the end of PNE to evaluate inflammatory serum biomarker levels. The primary objective is to evaluate whether PNE leads to clinical improvement in QoL and pain. If successful, it will be validated in a larger multi-centric cohort, potentially leading to its widespread implementation as a standard pain management tool for eTNBC patients.
Keywords: pain neuroscience education; triple-negative breast cancer; pain; biomedical education; neuropathy; migraine; quality of life; painful syndromes; disability pain neuroscience education; triple-negative breast cancer; pain; biomedical education; neuropathy; migraine; quality of life; painful syndromes; disability

Share and Cite

MDPI and ACS Style

Tiberio, P.; Balordi, M.; Castaldo, M.; Viganò, A.; Jacobs, F.; Benvenuti, C.; Torrisi, R.; Zambelli, A.; Santoro, A.; De Sanctis, R. Empowerment, Pain Control, and Quality of Life Improvement in Early Triple-Negative Breast Cancer Patients through Pain Neuroscience Education: A Prospective Cohort Pilot Study Protocol (EMPOWER Trial). J. Pers. Med. 2024, 14, 711. https://doi.org/10.3390/jpm14070711

AMA Style

Tiberio P, Balordi M, Castaldo M, Viganò A, Jacobs F, Benvenuti C, Torrisi R, Zambelli A, Santoro A, De Sanctis R. Empowerment, Pain Control, and Quality of Life Improvement in Early Triple-Negative Breast Cancer Patients through Pain Neuroscience Education: A Prospective Cohort Pilot Study Protocol (EMPOWER Trial). Journal of Personalized Medicine. 2024; 14(7):711. https://doi.org/10.3390/jpm14070711

Chicago/Turabian Style

Tiberio, Paola, Marco Balordi, Matteo Castaldo, Alessandro Viganò, Flavia Jacobs, Chiara Benvenuti, Rosalba Torrisi, Alberto Zambelli, Armando Santoro, and Rita De Sanctis. 2024. "Empowerment, Pain Control, and Quality of Life Improvement in Early Triple-Negative Breast Cancer Patients through Pain Neuroscience Education: A Prospective Cohort Pilot Study Protocol (EMPOWER Trial)" Journal of Personalized Medicine 14, no. 7: 711. https://doi.org/10.3390/jpm14070711

APA Style

Tiberio, P., Balordi, M., Castaldo, M., Viganò, A., Jacobs, F., Benvenuti, C., Torrisi, R., Zambelli, A., Santoro, A., & De Sanctis, R. (2024). Empowerment, Pain Control, and Quality of Life Improvement in Early Triple-Negative Breast Cancer Patients through Pain Neuroscience Education: A Prospective Cohort Pilot Study Protocol (EMPOWER Trial). Journal of Personalized Medicine, 14(7), 711. https://doi.org/10.3390/jpm14070711

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop