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Open AccessReview
Advanced Sperm Selection Techniques for Assisted Reproduction
by
Federica Cariati
Federica Cariati
,
Maria Grazia Orsi
Maria Grazia Orsi
Francesca Bagnulo
Francesca Bagnulo
Daniela Del Mondo
Daniela Del Mondo
Luigi Vigilante
Luigi Vigilante
Martina De Rosa
Martina De Rosa
Romualdo Sciorio
Romualdo Sciorio
Alessandro Conforti
Alessandro Conforti
Alessandro Conforti obtained his MD degree in 2009 and in
2010 he was a Clinical Visitor in IVF at [...]
Alessandro Conforti obtained his MD degree in 2009 and in
2010 he was a Clinical Visitor in IVF at Hammersmith Hospital, London UK
directed by Mr Stuart Lavery. During his specialization training, he worked in
the Minimally Invasive Therapy Unit & Endoscopy Training Center at the
Royal Free Hospital as a Clinical Research Fellow under the guidance of Mr Adam
Magos, Consultant Gynaecologist, from 2012 to 2013. During this period, he
worked as a Clinical Research Fellow in the Fetal Medicine Unit under the
guidance of Mr Demetrios Economides, Head of the Fetal Medicine Unit, at the
Royal Free Hospital, London. He acquired his specialty in Obstetrics and
Gynaecology in 2015. In 2017, he obtained his Ph.D. from the University of
Naples Federico II, with a thesis in Neuroscience and Reproductive Medicine
devoted to the role of genetic variants of gonadotropins and their receptors in
controlled ovarian stimulation. Since 2019, he has been an Assistant Professor in
Obstetrics and Gynecology at the University of Naples Federico II. His research
interests focus on Minimally Invasive and Reproductive Gynecological Surgery,
Reproductive Medicine, Reproductive Genetics, ART and Oncofertility.
Steven Fleming
Steven Fleming
Carlo Alviggi
Carlo Alviggi
1
Department of Public Health, School of Medicine, University of Naples Federico II, 80131 Naples, Italy
2
Fertility Unit, Maternal-Child Department, AOU Federico II Polyclinic, 80131 Naples, Italy
3
Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy
4
Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy
5
Fertility Medicine and Gynaecological Endocrinology Unit, Department Woman Mother Child, Lausanne University Hospital, 1011 Lausanne, Switzerland
6
Discipline of Anatomy & Histology, School of Medical Sciences, University of Sydney, Sydney, NSW 2050, Australia
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2024, 14(7), 726; https://doi.org/10.3390/jpm14070726 (registering DOI)
Submission received: 6 May 2024
/
Revised: 30 June 2024
/
Accepted: 2 July 2024
/
Published: 4 July 2024
Abstract
: Male infertility accounts for approximately 40% of infertility cases. There are many causes of male infertility, including environmental factors, age, lifestyle, infections, varicocele, and cancerous pathologies. Severe oligozoospermia, cryptozoospermia, and azoospermia (obstructive and non-obstructive) are identified as severe male factor infertility, once considered conditions of sterility. Today, in vitro fertilization (IVF) techniques are the only treatment strategy in cases of male factor infertility for which new methodologies have been developed in the manipulation of spermatozoa to achieve fertilization and increase success rates. This review is an update of in vitro manipulation techniques, in particular sperm selection, emphasizing clinical case-specific methodology. The success of an IVF process is related to infertility diagnosis, appropriate choice of treatment, and effective sperm preparation and selection. In fact, selecting the best spermatozoa to guarantee an optimal paternal heritage means increasing the blastulation, implantation, ongoing pregnancy and live birth rates, resulting in the greater success of IVF techniques.
Share and Cite
MDPI and ACS Style
Cariati, F.; Orsi, M.G.; Bagnulo, F.; Del Mondo, D.; Vigilante, L.; De Rosa, M.; Sciorio, R.; Conforti, A.; Fleming, S.; Alviggi, C.
Advanced Sperm Selection Techniques for Assisted Reproduction. J. Pers. Med. 2024, 14, 726.
https://doi.org/10.3390/jpm14070726
AMA Style
Cariati F, Orsi MG, Bagnulo F, Del Mondo D, Vigilante L, De Rosa M, Sciorio R, Conforti A, Fleming S, Alviggi C.
Advanced Sperm Selection Techniques for Assisted Reproduction. Journal of Personalized Medicine. 2024; 14(7):726.
https://doi.org/10.3390/jpm14070726
Chicago/Turabian Style
Cariati, Federica, Maria Grazia Orsi, Francesca Bagnulo, Daniela Del Mondo, Luigi Vigilante, Martina De Rosa, Romualdo Sciorio, Alessandro Conforti, Steven Fleming, and Carlo Alviggi.
2024. "Advanced Sperm Selection Techniques for Assisted Reproduction" Journal of Personalized Medicine 14, no. 7: 726.
https://doi.org/10.3390/jpm14070726
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