Advances in the Management of Localized Scleroderma: A Systematic Review of Laser Therapy and Injectable Filler Approaches
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Search Strategy
2.3. Inclusion Criteria
2.4. Data Collection
2.5. Assessment of the Quality of Included Studies
2.6. Data Synthesis
3. Results
3.1. Search Results and Narrative Synthesis
3.2. Treatment Options for Morphea
3.3. Hyaluronic Acid Filler and UVA1 Phototherapy
3.4. 585 nm Pulsed Dye Laser
3.5. Microcannula Filler Injections
3.6. Hyaluronic Acid Filler: Case Series
3.7. Hyaluronic Acid Filler: Clinical Effects
3.8. Combination Therapy: Systemic Methotrexate and Excimer Laser
3.9. Morphea Treatment for Functional Recovery: Fractional Ablative Laser
3.10. Polymethylmethacrylate Fillers
3.11. Differential Diagnosis and PDL Laser
Authors | Year | N | Sex | Age | Anatomical Site | Laser Therapy | Filler |
---|---|---|---|---|---|---|---|
Owczarczyk-Saczonek et al. [22] | 2020 | 3 | F | 17 | face | no | yes |
F | 16 | face and trunk | no | yes | |||
F | 70 | face and trunk | Fractional ablative CO2 | yes | |||
Choksi AN & Orringer JS [26] | 2011 | 1 | M | 20 | face | no | yes |
Eisen D et al. [27] | 2002 | 1 | F | 14 | face | Pulsed dye laser | no |
Thareja et al. [28] | 2015 | 1 | F | 44 | face | no | yes |
Hanson A et al. [29] | 2014 | 1 | F | 17 | trunk | Excimer laser | no |
Kineston D et al. [30] | 2011 | 1 | F | 27 | foot | Fractional ablative CO2 | no |
Franco JP et al. [31] | 2016 | 1 | M | 14 | face | no | yes |
Ng SS & Tay YK [32] | 2015 | 1 | F | 7 | face | Pulsed dye laser | no |
Sivek R & Emer J [34] | 2014 | 1 | F | N/A | face | no | yes |
4. Discussion
4.1. Dermal Fillers
4.2. Laser Therapy
4.3. Synergy between Fillers and Laser Therapy: ‘Two Is Better’?
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Cassalia, F.; Federico, S.; Danese, A.; Franceschin, L.; Amato, S.; Gratteri, F.; Battilotti, C.; Caroppo, F.; Zappia, E.; Bennardo, L.; et al. Advances in the Management of Localized Scleroderma: A Systematic Review of Laser Therapy and Injectable Filler Approaches. J. Pers. Med. 2024, 14, 872. https://doi.org/10.3390/jpm14080872
Cassalia F, Federico S, Danese A, Franceschin L, Amato S, Gratteri F, Battilotti C, Caroppo F, Zappia E, Bennardo L, et al. Advances in the Management of Localized Scleroderma: A Systematic Review of Laser Therapy and Injectable Filler Approaches. Journal of Personalized Medicine. 2024; 14(8):872. https://doi.org/10.3390/jpm14080872
Chicago/Turabian StyleCassalia, Fortunato, Serena Federico, Andrea Danese, Ludovica Franceschin, Simone Amato, Francesco Gratteri, Chiara Battilotti, Francesca Caroppo, Elena Zappia, Luigi Bennardo, and et al. 2024. "Advances in the Management of Localized Scleroderma: A Systematic Review of Laser Therapy and Injectable Filler Approaches" Journal of Personalized Medicine 14, no. 8: 872. https://doi.org/10.3390/jpm14080872