Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study
Abstract
1. Introduction
2. Materials and Methods
2.1. Report Translation
2.2. Comprehension Assessment
2.3. Participants
2.4. Data Analysis
3. Results
3.1. Survey Results and MAPL PGx Literacy
3.2. PGx Report Modifications
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Demographic Category | Frequency (%) |
---|---|
Age | |
25–34 | 20 (19) |
35–44 | 14 (13) |
45–54 | 22 (21) |
55–64 | 22 (21) |
65+ | 29 (27) |
Gender | |
Male | 36 (34) |
Female | 71 (66) |
Race | |
White | 72 (68) |
Black | 13 (12) |
Asian | 9 (8) |
Native American | 2 (2) |
Other | 11 (10) |
Ethnicity | |
Hispanic/Latino | 25 (23) |
Education Level | |
High School | 16 (15) |
Some College | 30 (28) |
Associate Degree in College (2-Year) | 7 (7) |
Bachelor’s Degree in College (4-Year) | 39 (36) |
Graduate or Professional Degree | 15 (14) |
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Amato, R.; Del Toro-Pagan, N.M.; Nguyen, H.; Plummer, J.; Pizzolato, K.; Krause, D.; Dowd, D. Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study. J. Pers. Med. 2025, 15, 247. https://doi.org/10.3390/jpm15060247
Amato R, Del Toro-Pagan NM, Nguyen H, Plummer J, Pizzolato K, Krause D, Dowd D. Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study. Journal of Personalized Medicine. 2025; 15(6):247. https://doi.org/10.3390/jpm15060247
Chicago/Turabian StyleAmato, Russell, Nicole M. Del Toro-Pagan, Harris Nguyen, Jordan Plummer, Katie Pizzolato, David Krause, and Daniel Dowd. 2025. "Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study" Journal of Personalized Medicine 15, no. 6: 247. https://doi.org/10.3390/jpm15060247
APA StyleAmato, R., Del Toro-Pagan, N. M., Nguyen, H., Plummer, J., Pizzolato, K., Krause, D., & Dowd, D. (2025). Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study. Journal of Personalized Medicine, 15(6), 247. https://doi.org/10.3390/jpm15060247