Composite Coating Prepared with Ferulic Acid to Improve the Corrosion Resistance and Blood Compatibility of Magnesium Alloy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Materials
2.2. Preparation of PDA-FA Composite Coating on Mg-Zn-Y-Nd Alloy
2.3. Characterization of the Mg-OH/PDA/FA Composite Coating
2.4. Blood Compatibility Tests
2.4.1. Adhesion and Degeneration of Fibrinogen
2.4.2. Platelet Adhesion Test
2.4.3. Hemolysis Test
2.5. DPPH Free Radical Content Test
2.6. Statistical Analysis
3. Results and Discussion
3.1. Surface Characterization
3.2. Corrosion Resistance Tests
3.3. Blood Compatibility Tests
3.4. DPPH Free Radical Content Test
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Roth, G.A.; Johnson, C.; Abajobir, A.; Abd-Allah, F.; Abera, S.F.; Abyu, G.; Ahmed, M.; Aksut, B.; Alam, T.; Alam, K.; et al. Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015. J. Am. Coll. Cardiol. 2017, 70, 1–25. [Google Scholar] [CrossRef] [PubMed]
- Li, J. Advanced Biomaterials for Drug Delivery and Tissue Regeneration. Curr. Drug Deliv. 2021, 18, 834–835. [Google Scholar] [CrossRef] [PubMed]
- Crimi, G.; Gritti, V.; Galiffa, V.A.; Scotti, V.; Leonardi, S.; Ferrario, M.; Ferlini, M.; De Ferrari, G.M.; Visconti, L.O.; Klersy, C. Drug eluting stents are superior to bare metal stents to reduce clinical outcome and stent-related complications in CKD patients, a systematic review, meta-analysis and network meta-analysis. J. Interv. Cardiol. 2018, 31, 319–329. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Wei, S.; Xu, Y.; Wang, Z.; Li, M.; Sun, P.; Xie, B.; Xing, Y.; Bai, H.; Kan, Q.; Li, J.; et al. Hydrogel-coated needles prevent puncture site bleeding. Acta Biomater. 2021, 128, 305–313. [Google Scholar] [CrossRef] [PubMed]
- Iakovou, I.; Schmidt, T.; Bonizzoni, E.; Ge, L.; Sangiorgi, G.M.; Stankovic, G.; Airoldi, F.; Chieffo, A.; Montorfano, M.; Carlino, M.; et al. Incidence, Predictors, and Outcome of Thrombosis After Successful Implantation of Drug-Eluting Stents. JAMA 2005, 293, 2126–2130. [Google Scholar] [CrossRef]
- Yu, Y.; Zhu, S.; Hou, Y.; Li, J.; Guan, S. Sulfur contents in sulfonated hyaluronic acid direct the cardiovascular cells fate. ACS Appl. Mater. Interfaces 2020, 12, 46827–46836. [Google Scholar] [CrossRef]
- Sketch, M.H.; Ball, M.; Rutherford, B.; Popma, J.J.; Russell, C.; Kereiakes, D.J.; on behalf of the Driver Investigators. Evaluation of the Medtronic (Driver) cobalt-chromium alloy coronary stent system. Am. J. Cardiol. 2005, 95, 8–12. [Google Scholar] [CrossRef]
- Dong, H.; Li, D.; Mao, D.; Bai, N.; Chen, Y.; Li, Q. Enhanced performance of magnesium alloy for drug-eluting vascular scaffold application. Appl. Surf. Sci. 2018, 435, 320–328. [Google Scholar] [CrossRef]
- Hou, Y.; Witte, F.; Li, J.; Guan, S. The increased ratio of Mg2+/Ca2+ from degrading magnesium alloys directs macrophage fate for functionalized growth of endothelial cells. Smart Mater. Med. 2022, 3, 188–198. [Google Scholar] [CrossRef]
- Witte, F.; Hort, N.; Vogt, C.; Cohen, S.; Kainer, K.U.; Willumeit, R.; Feyerabend, F. Degradable biomaterials based on magnesium corrosion. Curr. Opin. Solid State Mater. Sci. 2008, 12, 63–72. [Google Scholar] [CrossRef] [Green Version]
- Liu, C.; Hou, Y.; Li, J. A mini review on biodegradable magnesium alloy vascular stent. Adv. Mater. Lett. 2020, 11, 20101563. [Google Scholar] [CrossRef]
- Zhao, Z.; Moghadasian, M.H. Chemistry, natural sources, dietary intake and pharmacokinetic properties of ferulic acid: A review. Food Chem. 2008, 109, 691–702. [Google Scholar] [CrossRef] [PubMed]
- Kumar, N.; Pruthi, V. Potential applications of ferulic acid from natural sources. Biotechnol. Rep. 2014, 4, 86–93. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sanduk, F.; Meng, Y.; Widera, D.; Kowalczyk, R.M.; Michael, N.; Kaur, A.; Yip, V.; Zulu, S.; Zavrou, I.; Hana, L.; et al. Enhanced anti-inflammatory potential of degradation resistant curcumin/ferulic acid eutectics embedded in triglyceride-based microemulsions. J. Drug Deliv. Sci. Technol. 2020, 60, 102067. [Google Scholar] [CrossRef]
- Wang, B.H.; Ou-Yang, J.P. Pharmacological Actions of Sodium Ferulate in Cardiovascular System. Cardiovasc. Drug Rev. 2010, 23, 161–172. [Google Scholar] [CrossRef]
- Lin, C.M.; Chiu, J.H.; Wu, I.H.; Wang, B.W.; Pan, C.M.; Chen, Y.H. Ferulic acid augments angiogenesis via VEGF, PDGF and HIF-1 alpha. J. Nutr. Biochem. 2010, 21, 627–633. [Google Scholar] [CrossRef]
- Wang, J.; Yuan, Z.; Zhao, H.; Ju, D.; Chen, Y.; Chen, X.; Zhang, J. Ferulic acid promotes endothelial cells proliferation through up-regulating cyclin D1 and VEGF. J. Ethnopharmacol. 2011, 137, 992–997. [Google Scholar] [CrossRef]
- Hou, Y.Z.; Yang, J.; Zhao, G.R.; Yuan, Y.J. Ferulic acid inhibits vascular smooth muscle cell proliferation induced by angiotensin II. Eur. J. Pharmacol. 2004, 499, 85–90. [Google Scholar] [CrossRef]
- Zhang, E.; Shen, F. Blood compatibility of a ferulic acid (FA)-eluting PHBHHx system for biodegradable magnesium stent application. Mater. Sci. Eng. C Mater. Biol. Appl. 2015, 52, 37–45. [Google Scholar] [CrossRef]
- Li, J.; Chen, L.; Zhang, X.; Guan, S. Enhancing biocompatibility and corrosion resistance of biodegradable Mg-Zn-Y-Nd alloy by preparing PDA/HA coating for potential application of cardiovascular biomaterials. Mater. Sci. Eng. C 2020, 109, 110607. [Google Scholar] [CrossRef]
- Liang, J.; Cui, L.; Li, J.K.; Guan, S.; Zhang, K.; Li, J. Aloe vera: A medicinal plant used in skin wound healing. Tissue Eng. Part B Rev. 2021, 27, 455–474. [Google Scholar] [CrossRef] [PubMed]
- Wei, S.; Li, J.; He, H.; Shu, C.; Dardik, A.; Bai, H. A three-layered hydrogel patch with hierarchy releasing of PLGA nanoparti-cle drugs decrease neointimal hyperplasia. Smart Mater. Med. 2022, 3, 139–147. [Google Scholar] [CrossRef]
- Ho, C.C.; Ding, S.J. Structure, properties and applications of mussel-inspired polydopamine. J. Biomed. Nanotechnol. 2014, 10, 3063–3084. [Google Scholar] [CrossRef] [PubMed]
- Chen, D.; Wang, R.; Huang, Z.; Wu, Y.; Zhang, Y.; Wu, G.; Li, D.; Guo, C.; Jiang, G.; Yu, S.; et al. Evolution processes of the corrosion behavior and structural characteristics of plasma electrolytic oxidation coatings on AZ31 magnesium alloy. Appl. Surf. Sci. 2018, 434, 326–335. [Google Scholar] [CrossRef]
- Liu, X.; Zhen, Z.; Liu, J.; Xi, T.; Zheng, Y.; Guan, S.; Zheng, Y.; Cheng, Y. Multifunctional MgF2/Polydopamine Coating on Mg Alloy for Vascular Stent Application. J. Mater. Sci. Technol. 2015, 31, 733–743. [Google Scholar] [CrossRef]
- Tong, P.; Sheng, Y.; Hou, R.; Iqbal, M.; Chen, L.; Li, J. Recent progress on coatings of biomedical magnesium alloy. Smart Mater. Med. 2022, 3, 104–116. [Google Scholar] [CrossRef]
- Yang, Y.X.; Fang, Z.; Liu, Y.H.; Hou, Y.C.; Wang, L.G.; Zhou, Y.F.; Zhu, S.J.; Zeng, R.C.; Zheng, Y.F.; Guan, S.K. Biodegradation, hemocompatibility and covalent bonding mechanism of electrografting polyethylacrylate coating on Mg alloy for cardiovascular stent. J. Mater. Sci. Technol. 2020, 46, 114–126. [Google Scholar] [CrossRef]
- Huang, W.; Mei, D.; Liu, Y.; Wang, L.; Zhou, Y.; Zhu, S.; Guan, S. A simple approach for synthesizing polyglycolide coating on magnesium alloy. Mater. Lett. 2021, 298, 130046. [Google Scholar] [CrossRef]
- Liu, J.; Zheng, B.; Wang, P.; Wang, X.; Zhang, B.; Shi, Q.; Xi, T.; Chen, M.; Guan, S. Enhanced in Vitro and in Vivo Performance of Mg-Zn-Y-Nd Alloy Achieved with APTES Pretreatment for Drug-Eluting Vascular Stent Application. ACS Appl. Mater. Interfaces 2016, 8, 17842–17858. [Google Scholar] [CrossRef]
- Liu, J.; Xi, T. Enhanced Anti-corrosion Ability and Biocompatibility of PLGA Coatings on MgZnYNd Alloy by BTSE-APTES Pre-treatment for Cardiovascular Stent. J. Mater. Sci. Technol. 2016, 32, 845–857. [Google Scholar] [CrossRef]
- Sheng, Y.; Yang, J.; Hou, R.; Chen, L.; Xu, J.; Liu, H.; Zhao, X.; Wang, X.; Zeng, R.; Li, W.; et al. Improved biocompatibility and degradation behavior of biodegradable Zn-1Mg by grafting zwitterionic phosphorylcholine chitosan (PCCs) coating on silane pre-modified surface. Appl. Surf. Sci. 2020, 527, 146914. [Google Scholar] [CrossRef]
- Chen, Y.; Wan, G.; Wang, J.; Zhao, S.; Zhao, Y.; Huang, N. Covalent immobilization of phytic acid on Mg by alkaline pre-treatment: Corrosion and degradation behavior in phosphate buffered saline. Corros. Sci. 2013, 75, 280–286. [Google Scholar] [CrossRef]
- Yang, Z.; Xiong, K.; Qi, P.; Yang, Y.; Tu, Q.; Wang, J.; Huang, N. Gallic acid tailoring surface functionalities of plasma-polymerized allylamine-coated 316L SS to selectively direct vascular endothelial and smooth muscle cell fate for enhanced endothelialization. ACS Appl. Mater. Interfaces 2014, 6, 2647–2656. [Google Scholar] [CrossRef]
- Chen, L.; Li, J.; Chang, J.; Jin, S.; Wu, D.; Yan, H.; Wang, X.; Guan, S. Mg-Zn-Y-Nd coated with citric acid and dopamine by layer-by-layer self-assembly to improve surface biocompatibility. Sci. China Technol. Sci. 2018, 61, 1228–1237. [Google Scholar] [CrossRef]
- Li, J.; Li, W.; Zou, D.; Kou, F.; Hou, Y.; Yasin, A.; Zhang, K. Comparison of conjugating chondroitin sulfate A and B on amine-rich surface: For deeper understanding on directing cardiovascular cells fate. Compos. Part B Eng. 2022, 228, 109430. [Google Scholar] [CrossRef]
- Bai, H.; Sun, P.; Wu, H.; Wei, S.; Xie, B.; Wang, W.; Hou, Y.; Li, J.; Dardik, A.; Li, Z. The application of tissue-engineered fish swim bladder vascular graft. Commun. Biol. 2021, 4, 1153. [Google Scholar] [CrossRef] [PubMed]
- Yu, Y.; Zhu, S.J.; Dong, H.T.; Zhang, X.Q.; Li, J.A.; Guan, S.K. A novel MgF2/PDA/S-HA coating on the biodegradable ZE21B alloy for better multi-functions on cardiovascular application. J. Magnes. Alloys 2021. [Google Scholar] [CrossRef]
- Zou, D.; Li, J.; Kou, F.; Luo, X.; Yang, P. Reveal crucial subtype of natural chondroitin sulfate on the functionalized coatings for cardiovascular implants. J. Mater. Sci. Technol. 2021, 91, 67–77. [Google Scholar] [CrossRef]
- Li, J.; Wang, S.; Sheng, Y.; Liu, C.; Xue, Z.; Tong, P.; Guan, S. Designing HA/PEI nanoparticle composite coating on biodegradable Mg-Zn-Y-Nd alloy to direct cardiovascular cells fate. Smart Mater. Med. 2021, 2, 124–136. [Google Scholar] [CrossRef]
- Kou, F.; Liu, C.; Wang, L.; Yasin, A.; Li, J.; Guan, S. Fabrication of Citric Acid/RGD Multilayers on Mg-Zn-Y-Nd Alloy via Layer-by-Layer Self-Assembly for Promoting Surface Biocompatibility. Adv. Mater. Interfaces 2021, 8, 2002241. [Google Scholar] [CrossRef]
- Wu, Y.; Chang, L.; Li, J.; Wang, L.; Guan, S. Conjugating heparin, REDV peptide and anti-CD34 to the silanic Mg-Zn-Y-Nd alloy for better endothelialization. J. Biomater. Appl. 2020, 35, 158–168. [Google Scholar] [CrossRef] [PubMed]
- Xu, R.; Zhang, K.; Liang, J.; Gao, F.; Li, J.; Guan, F. Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer. Carbohydr. Polym. 2021, 261, 117846. [Google Scholar] [CrossRef] [PubMed]
- Wei, Z.; Tian, P.; Liu, X.; Zhou, B. In vitro degradation, hemolysis, and cytocompatibility of PEO/PLLA composite coating on biodegradable AZ31 alloy. J. Biomed. Mater. Res. Part B 2015, 103B, 342–354. [Google Scholar] [CrossRef] [PubMed]
Samples | Ecorr (V) | Icorr (A/cm2) |
---|---|---|
Mg-Zn-Y-Nd | −1.71 | 1.08 × 10−4 |
Mg-OH | −1.55 | 2.47 × 10−6 |
PDA | −1.47 | 6.50 × 10−7 |
FA-1 h | −1.43 | 3.44 × 10−7 |
FA-3 h | −1.36 | 2.06 × 10−7 |
FA-6 h | −1.52 | 1.24 × 10−6 |
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Han, Z.; Guo, H.; Zhou, Y.; Wang, L.; Zhang, K.; Li, J.-a. Composite Coating Prepared with Ferulic Acid to Improve the Corrosion Resistance and Blood Compatibility of Magnesium Alloy. Metals 2022, 12, 545. https://doi.org/10.3390/met12040545
Han Z, Guo H, Zhou Y, Wang L, Zhang K, Li J-a. Composite Coating Prepared with Ferulic Acid to Improve the Corrosion Resistance and Blood Compatibility of Magnesium Alloy. Metals. 2022; 12(4):545. https://doi.org/10.3390/met12040545
Chicago/Turabian StyleHan, Zhijin, Haojie Guo, Yifan Zhou, Liguo Wang, Kun Zhang, and Jing-an Li. 2022. "Composite Coating Prepared with Ferulic Acid to Improve the Corrosion Resistance and Blood Compatibility of Magnesium Alloy" Metals 12, no. 4: 545. https://doi.org/10.3390/met12040545