An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative Stress
Abstract
:1. Introduction
2. The Generation of Free Radicals inside SM and Way to Deal with Them
3. The Significance of Physical Exercise in the Generation of Free Radicals in SM
4. The Influence of Antioxidant Supplementation on SM
4.1. In Terms of Adaptations to Training
4.2. In Terms of Inflammation
4.3. In Terms of Muscle Damage
5. Disorders Related to Loss of Strength and SM Mass, Antioxidant Supplements and Physical Exercise
5.1. DMD, Antioxidant Supplementation, and Exercise
5.2. Sarcopenia, Antioxidant Supplementation, and Exercise
Reference | Subjects | Antioxidant Supplementation | Exercise Training | Results |
---|---|---|---|---|
Paulsen et al. [55] | Strength-trained recreational men and women | Vitamins E and C (235 mg per day and 1000 mg per day, respectively) for ten weeks | Heavy-duty resistance training four times a week | No increase in muscle mass |
Makanae et al. [56] | Wistar rats | Vitamin C (500 mg kg−1) for 14 days | Mechanical overload | Decrease of hypertrophy of overworked muscles |
Theodorou et al. [57] | Exercised-recreational men | Vitamins E and C (400 IU and 1000 mg per day) for 11 weeks | Eccentric exercise for four weeks and twice a week | No impact on muscular function or recovery following exercise |
Dutra et al. [58] | Healthy and non-smoking women | Vitamins E and C (400 IU and 1000 mg daily, respectively) | Ten weeks of twice-weekly strength training (ST) | Decrease of peak torque and total work due to taking antioxidant supplements |
Cooke et al. [60] | Trained and untrained men and women | 200 mg of COQ10 every day for 14 days | WT GXT and Isokinetic tests | Higher CoQ10 levels did not affect the individuals physical endurance |
Taub et al. [61] | Healthy and sedentary adults | 20 g of dark chocolate for three months | Stationary bike ride | Increase of VO2max |
Bowtell et al. [65] | Trained men | 30 mL (twice daily) of Montmorency cherry juice for one week before and 48 h after exercise | Ten sets of 10 repetitions with a single knee extension at 80% of their maximal repetition | Improvement of muscular isometric strength following intensive exercise |
McLeay et al. [66] | Healthy women | Blueberry smoothie 5 and 10 h before EIMD and immediately, 12 and 36 h afterwards | Exercise-induced muscle damage (EIMD) | Increase of isometric muscular strength recovery |
Furlong et al. [67] | Untrained people | Proprietary herbal/botanical combination (1575 mg 2 times a day), and Aphanizomenon flos-aquae extract (1000 mg 3 times daily) | Resistance training regimen (3 times a week, two sets of 10 repetitions per movement, for 12 weeks) | No variations in the patients balance, strength, or muscular function |
Carrera-Quintanar et al. [73] | University-level athletes | Vitamins C and E and Lippia citriodora antioxidant extract | 2000-m running test. | Protect neutrophils from oxidative injury to skeletal muscle |
Rokitzki et al. [82] | Running athletes | 200 mg of vitamin C and 600 mg of vitamin E daily for five weeks | ------------------- | Decrease of muscular damage |
Zoppi et al. [83] | Soccer players | 1000 mg of vitamin C and 800 mg of vitamin E for twelve weeks | ------------------- |
|
Dawson et al. [84] | Well-trained runners | 500 to 1000 mg of vitamin C and 750 to 1500 mg of vitamin E per day | ------------------- |
|
Nieman et al. [85] | Well-trained runners | Quercetin antioxidant supplement (500 mg/day) for three weeks | ------------------- |
|
Kon et al. [86] | Kendo athletes | CoQ10 (300 mg/day) for 20 days | ------------------- |
|
Orlando et al. [87] | Rugby participants | CoQ10 (200 mg/day) for 1 month | ------------------- |
|
O’Fallen et al. [88] | Young men and women | Quercetin (100 mg daily) | ------------------- |
|
Liang et al. [103] | Male Sprague-Dawley rats | BSP supplementation | Treadmill and grip strength tests | Improvement of grip strength, muscular mass, and muscular endurance |
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Taherkhani, S.; Valaei, K.; Arazi, H.; Suzuki, K. An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative Stress. Antioxidants 2021, 10, 1528. https://doi.org/10.3390/antiox10101528
Taherkhani S, Valaei K, Arazi H, Suzuki K. An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative Stress. Antioxidants. 2021; 10(10):1528. https://doi.org/10.3390/antiox10101528
Chicago/Turabian StyleTaherkhani, Shima, Kosar Valaei, Hamid Arazi, and Katsuhiko Suzuki. 2021. "An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative Stress" Antioxidants 10, no. 10: 1528. https://doi.org/10.3390/antiox10101528