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Correction to Antioxidants 2022, 11(9), 1787.
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Correction

Correction: Zhang et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787

by
Jinfu Zhang
1,2,†,
Siyi Hu
3,†,
Changzhi Zhao
1,
Yuan Zhou
1,
Lu Zhang
1,
Hailong Liu
1,
Peng Zhou
1,
Sheng Li
1,
Liangliang Fu
1,
Zhuqing Zheng
1,
Yue Xiang
1,
Xuewen Xu
1,2,
Jinxue Ruan
1,
Xinyun Li
1,4,5,
Lvhui Sun
4,
Gang Cao
4,
Shuhong Zhao
1,2,4,5,*,
Xu Wang
3,* and
Shengsong Xie
1,2,4,5,*
1
Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Lab of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China
2
Guangdong Laboratory of Lingnan Modern Agriculture, Guangzhou 510642, China
3
National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan 430070, China
4
Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan 430070, China
5
The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Antioxidants 2023, 12(2), 446; https://doi.org/10.3390/antiox12020446
Submission received: 6 February 2023 / Accepted: 7 February 2023 / Published: 10 February 2023
Browse Figure
Versions Notes
In the original publication [1], a mistake was identified in Figure 4 as published. The explanation in Figure 4E is wrong. The corrected Figure 4 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Zhang, J.; Hu, S.; Zhao, C.; Zhou, Y.; Zhang, L.; Liu, H.; Zhou, P.; Li, S.; Fu, L.; Zheng, Z.; et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787. [Google Scholar] [CrossRef] [PubMed]
Antioxidants 12 00446 g001 550
Figure 4. Treatment with inhibitor M2 leads to the highest resistance to aflatoxin B1 in vitro. (A) Workflow of the structure-based virtual screening to identify inhibitors targeting BACH1. (B) Validation of the top three inhibitors (M1, M2, and M3) in Huh7 cells by CCK-8 assays. (C) Comparation of Huh7 tolerance to different AFB1 concentrations with and without M2 treatment. (D) The relative fluorescence intensity of AFB1-DNA adducts in Huh7 cells with and without M2 treatment. (E) Representative light microscopy images of AFB1-treated PK-15 cells with or without M2 treatment. Scale bar, 100 μm. (F) The IC50 assays for AFB1 in PK-15 cells with and without M2 treatment determined with CCK-8 assays. (G) The relative fluorescence intensity of AFB1-DNA adducts in PK-15 cells with and without M2 treatment. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns, not significant. p values were determined with two-tailed Student’s t-tests. AFB1, aflatoxin B1; M1, 1-Piperazineethanol, 4-phenyl-α-[[(3,4,5-trimethoxyphenyl)methoxy]methyl]; M2, 1-Piperazineethanol,α-[(1,3-benzodioxol-5-yloxy)methyl]-4-(2-methoxyphenyl); M3, 1,2-Ethanediamine, N1, N1, N2, N2-tetrakis (1H-benzimidazol-2-ylmethyl).
Figure 4. Treatment with inhibitor M2 leads to the highest resistance to aflatoxin B1 in vitro. (A) Workflow of the structure-based virtual screening to identify inhibitors targeting BACH1. (B) Validation of the top three inhibitors (M1, M2, and M3) in Huh7 cells by CCK-8 assays. (C) Comparation of Huh7 tolerance to different AFB1 concentrations with and without M2 treatment. (D) The relative fluorescence intensity of AFB1-DNA adducts in Huh7 cells with and without M2 treatment. (E) Representative light microscopy images of AFB1-treated PK-15 cells with or without M2 treatment. Scale bar, 100 μm. (F) The IC50 assays for AFB1 in PK-15 cells with and without M2 treatment determined with CCK-8 assays. (G) The relative fluorescence intensity of AFB1-DNA adducts in PK-15 cells with and without M2 treatment. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns, not significant. p values were determined with two-tailed Student’s t-tests. AFB1, aflatoxin B1; M1, 1-Piperazineethanol, 4-phenyl-α-[[(3,4,5-trimethoxyphenyl)methoxy]methyl]; M2, 1-Piperazineethanol,α-[(1,3-benzodioxol-5-yloxy)methyl]-4-(2-methoxyphenyl); M3, 1,2-Ethanediamine, N1, N1, N2, N2-tetrakis (1H-benzimidazol-2-ylmethyl).
Antioxidants 12 00446 g001
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MDPI and ACS Style

Zhang, J.; Hu, S.; Zhao, C.; Zhou, Y.; Zhang, L.; Liu, H.; Zhou, P.; Li, S.; Fu, L.; Zheng, Z.; et al. Correction: Zhang et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787. Antioxidants 2023, 12, 446. https://doi.org/10.3390/antiox12020446

AMA Style

Zhang J, Hu S, Zhao C, Zhou Y, Zhang L, Liu H, Zhou P, Li S, Fu L, Zheng Z, et al. Correction: Zhang et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787. Antioxidants. 2023; 12(2):446. https://doi.org/10.3390/antiox12020446

Chicago/Turabian Style

Zhang, Jinfu, Siyi Hu, Changzhi Zhao, Yuan Zhou, Lu Zhang, Hailong Liu, Peng Zhou, Sheng Li, Liangliang Fu, Zhuqing Zheng, and et al. 2023. "Correction: Zhang et al. Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B1-Induced Oxidative Damage. Antioxidants 2022, 11, 1787" Antioxidants 12, no. 2: 446. https://doi.org/10.3390/antiox12020446

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