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Antioxidants
Volume 12
Issue 4
10.3390/antiox12040878
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Review

A Narrative Review of Lifestyle Risk Factors and the Role of Oxidative Stress in Age-Related Hearing Loss

by
Diana Tang
1,*,
Yvonne Tran
1,
Piers Dawes
2 and
Bamini Gopinath
1
1
Macquarie University Hearing, Faculty of Medicine Health and Human Sciences, Macquarie University, Sydney, NSW 2109, Australia
2
Centre for Hearing Research, School of Health and Rehabilitation Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
*
Author to whom correspondence should be addressed.
Antioxidants 2023, 12(4), 878; https://doi.org/10.3390/antiox12040878
Submission received: 9 March 2023 / Revised: 29 March 2023 / Accepted: 3 April 2023 / Published: 4 April 2023
(This article belongs to the Special Issue Oxidative Stress and Hearing Loss)
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Abstract

Age-related hearing loss affects a significant proportion of adults aged 60 years and above, with a prevalence of 65%. This condition has a negative impact on both physical and mental well-being, and while hearing interventions can help alleviate the effects of hearing loss, they cannot completely restore normal hearing or halt the progression of age-related hearing loss. Oxidative stress and inflammation have been identified as potential contributors to this condition. By addressing modifiable lifestyle risk factors that exacerbate oxidative stress, there may be an opportunity to prevent hearing loss. Therefore, this narrative review provides an overview of the major modifiable lifestyle risk factors associated with age-related hearing loss, that is, exposure to noise and ototoxic chemicals, smoking, diet, physical activity, and the presence of chronic lifestyle diseases, and offers an overview of the role of oxidative stress in the pathophysiology of this condition.
Keywords: hearing loss; adults; oxidative stress; lifestyle; noise; ototoxicity hearing loss; adults; oxidative stress; lifestyle; noise; ototoxicity

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MDPI and ACS Style

Tang, D.; Tran, Y.; Dawes, P.; Gopinath, B. A Narrative Review of Lifestyle Risk Factors and the Role of Oxidative Stress in Age-Related Hearing Loss. Antioxidants 2023, 12, 878. https://doi.org/10.3390/antiox12040878

AMA Style

Tang D, Tran Y, Dawes P, Gopinath B. A Narrative Review of Lifestyle Risk Factors and the Role of Oxidative Stress in Age-Related Hearing Loss. Antioxidants. 2023; 12(4):878. https://doi.org/10.3390/antiox12040878

Chicago/Turabian Style

Tang, Diana, Yvonne Tran, Piers Dawes, and Bamini Gopinath. 2023. "A Narrative Review of Lifestyle Risk Factors and the Role of Oxidative Stress in Age-Related Hearing Loss" Antioxidants 12, no. 4: 878. https://doi.org/10.3390/antiox12040878

APA Style

Tang, D., Tran, Y., Dawes, P., & Gopinath, B. (2023). A Narrative Review of Lifestyle Risk Factors and the Role of Oxidative Stress in Age-Related Hearing Loss. Antioxidants, 12(4), 878. https://doi.org/10.3390/antiox12040878

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