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Antioxidants
Volume 4
Issue 3
10.3390/antiox4030577
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Review

Periodontal Disease-Induced Atherosclerosis and Oxidative Stress

by
Tomoko Kurita-Ochiai
1,*,
Ru Jia
2,
Yu Cai
3,
Yohei Yamaguchi
4 and
Masafumi Yamamoto
1
1
Department of Microbiology and Immunology, Nihon University School of Dentistry at Matsudo, Chiba 271-8587, Japan
2
Stomatology Hospital, Tongji University, Shanghai 200072, China
3
Department of Periodontology, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, China
4
Department of Oral and Maxillofacial Surgery, School of Medicine, Tokyo Women's Medical University, Tokyo 162-8666, Japan
*
Author to whom correspondence should be addressed.
Antioxidants 2015, 4(3), 577-590; https://doi.org/10.3390/antiox4030577
Submission received: 9 July 2015 / Revised: 11 August 2015 / Accepted: 18 August 2015 / Published: 2 September 2015
(This article belongs to the Special Issue Antioxidants and Periodontal Diseases)
Versions Notes

Abstract

Periodontal disease is a highly prevalent disorder affecting up to 80% of the global population. Recent epidemiological studies have shown an association between periodontal disease and cardiovascular disease, as oxidative stress plays an important role in chronic inflammatory diseases such as periodontal disease and cardiovascular disease. In this review, we focus on the mechanisms by which periodontopathic bacteria cause chronic inflammation through the enhancement of oxidative stress and accelerate cardiovascular disease. Furthermore, we comment on the antioxidative activity of catechin in atherosclerosis accelerated by periodontitis.
Keywords: inflammation; oxidative stress; systemic chronic disease; atherosclerosis; periodontal disease inflammation; oxidative stress; systemic chronic disease; atherosclerosis; periodontal disease

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MDPI and ACS Style

Kurita-Ochiai, T.; Jia, R.; Cai, Y.; Yamaguchi, Y.; Yamamoto, M. Periodontal Disease-Induced Atherosclerosis and Oxidative Stress. Antioxidants 2015, 4, 577-590. https://doi.org/10.3390/antiox4030577

AMA Style

Kurita-Ochiai T, Jia R, Cai Y, Yamaguchi Y, Yamamoto M. Periodontal Disease-Induced Atherosclerosis and Oxidative Stress. Antioxidants. 2015; 4(3):577-590. https://doi.org/10.3390/antiox4030577

Chicago/Turabian Style

Kurita-Ochiai, Tomoko, Ru Jia, Yu Cai, Yohei Yamaguchi, and Masafumi Yamamoto. 2015. "Periodontal Disease-Induced Atherosclerosis and Oxidative Stress" Antioxidants 4, no. 3: 577-590. https://doi.org/10.3390/antiox4030577

APA Style

Kurita-Ochiai, T., Jia, R., Cai, Y., Yamaguchi, Y., & Yamamoto, M. (2015). Periodontal Disease-Induced Atherosclerosis and Oxidative Stress. Antioxidants, 4(3), 577-590. https://doi.org/10.3390/antiox4030577

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