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Membranes
Volume 11
Issue 2
10.3390/membranes11020087
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Review

Multitarget Approach to Cardiogenic Shock after Acute Myocardial Infarction: Extracorporeal Life Support (ECLS) and Beyond

by
Federico Pappalardo
1,*,
Giulia Malara
2 and
Andrea Montisci
2
1
Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, 90127 Palermo, Italy
2
Cardiothoracic Center, Department of Anesthesia and Intensive Care, Istituto Clinico Sant’Ambrogio, 20149 Milan, Italy
*
Author to whom correspondence should be addressed.
Membranes 2021, 11(2), 87; https://doi.org/10.3390/membranes11020087
Submission received: 7 January 2021 / Revised: 24 January 2021 / Accepted: 25 January 2021 / Published: 27 January 2021
(This article belongs to the Special Issue Advances in Extracorporeal Membrane Oxygenation)
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Abstract

Cardiogenic shock following acute myocardial infarction is associated with high mortality, substantially unchanged for the previous 20 years. Several approaches have been sought to achieve a therapeutic breakthrough, from myocardial revascularization strategies to the use of mechanical circulatory support. Many issues are, as yet, unresolved. Systemic inflammation seems to play a key role but is still lacking in effective therapies, and is potentially compounded by the death spiral of hypoperfusion and/or artificial devices. In this review, a multitarget approach to cardiogenic shock following acute myocardial infarction is proposed.
Keywords: cardiogenic shock; acute myocardial infarction; extracorporeal life support cardiogenic shock; acute myocardial infarction; extracorporeal life support

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MDPI and ACS Style

Pappalardo, F.; Malara, G.; Montisci, A. Multitarget Approach to Cardiogenic Shock after Acute Myocardial Infarction: Extracorporeal Life Support (ECLS) and Beyond. Membranes 2021, 11, 87. https://doi.org/10.3390/membranes11020087

AMA Style

Pappalardo F, Malara G, Montisci A. Multitarget Approach to Cardiogenic Shock after Acute Myocardial Infarction: Extracorporeal Life Support (ECLS) and Beyond. Membranes. 2021; 11(2):87. https://doi.org/10.3390/membranes11020087

Chicago/Turabian Style

Pappalardo, Federico, Giulia Malara, and Andrea Montisci. 2021. "Multitarget Approach to Cardiogenic Shock after Acute Myocardial Infarction: Extracorporeal Life Support (ECLS) and Beyond" Membranes 11, no. 2: 87. https://doi.org/10.3390/membranes11020087

APA Style

Pappalardo, F., Malara, G., & Montisci, A. (2021). Multitarget Approach to Cardiogenic Shock after Acute Myocardial Infarction: Extracorporeal Life Support (ECLS) and Beyond. Membranes, 11(2), 87. https://doi.org/10.3390/membranes11020087

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