Glutathione Disulfide as a Reducing, Capping, and Mass-Separating Agent for the Synthesis and Enrichment of Gold Nanoclusters
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Materials
2.2. Synthesis of GSSG–AuNCs and GSH–AuNCs
2.2.1. Heating Modes
2.2.2. Synthesis of GSSG–AuNCs
2.2.3. Synthesis of GSH–AuNCs
2.3. Characterization
2.4. Acetonitrile-Initiated Phase Separation
2.5. Density Functional Theory Calculation
3. Results and Discussion
3.1. Synthesis of GSSG–AuNCs
3.2. Photophysical Properties
3.3. Morphological and Compositional Investigations
3.4. Enrichment and Redispersion of GSSG–AuNCs
3.5. GSSG as the Mass-Separating Agent
3.6. Mechanism Studies
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Approach | Nanomaterials | Time | Enrichment Factor | Recovery | Ref. |
---|---|---|---|---|---|
Magnet solid-phase extraction | TiO2 nanoparticles | 25 min | 400 | 91.0–102.0% | [47] |
Nanofluidic device under electroless actuation mode | Polystyrene nanobeads | 60 min | 200 | n/a | [14] |
Brownian ratchet-based nanofluidic system | 100 nm polystyrene beads | 17 min | 27 | n/a | [46] |
C-18 column adsorption ligand-assisted liquid– liquid extraction | 10 nm gold nanoparticles | n/a | 250 | 68.4–99.4% | [28] |
Ultracentrifugation | Curcumin–chitosan nanocomplexes | >20 min | n.a. | 48% | [29] |
Acetonitrile-initiated phase separation | Gold nanoclusters | 10 min | 400 | 99.62% | This method |
GSSG | GSH | |
---|---|---|
–COOH | −6.15 | −5.99 |
–NH2 | −2.04 | −3.89 |
–CONH | −4.46 | −3.12 |
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Zhang, Q.; Wang, J.; Meng, Z.; Ling, R.; Ren, H.; Qin, W.; Wu, Z.; Shao, N. Glutathione Disulfide as a Reducing, Capping, and Mass-Separating Agent for the Synthesis and Enrichment of Gold Nanoclusters. Nanomaterials 2021, 11, 2258. https://doi.org/10.3390/nano11092258
Zhang Q, Wang J, Meng Z, Ling R, Ren H, Qin W, Wu Z, Shao N. Glutathione Disulfide as a Reducing, Capping, and Mass-Separating Agent for the Synthesis and Enrichment of Gold Nanoclusters. Nanomaterials. 2021; 11(9):2258. https://doi.org/10.3390/nano11092258
Chicago/Turabian StyleZhang, Qianqian, Junhua Wang, Zhao Meng, Rui Ling, Hang Ren, Weidong Qin, Zhenglong Wu, and Na Shao. 2021. "Glutathione Disulfide as a Reducing, Capping, and Mass-Separating Agent for the Synthesis and Enrichment of Gold Nanoclusters" Nanomaterials 11, no. 9: 2258. https://doi.org/10.3390/nano11092258