Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics
Abstract
:1. Introduction
Local Drug Delivery Systems and Titanium Implants
2. Antibacterial Effects
2.1. Anodizing Titania Nanotubes and Vancomycin
2.2. Electrochemical Deposition and Vancomycin
2.3. Chemical Coating and Vancomycin
3. Antitumor Effects
3.1. Titanium Nano/Micro-Surface Modification and Antitumor Activity
3.2. Chemical Coating and Antitumor Activity
4. Osseointegration Effect
4.1. Titanium Nano/Micro-Scale Surface Modification and Osseointegration
4.2. Chemical Coatings on Titanium Surfaces and Osseointegration
5. Discussion
5.1. Loaded Drugs and Their Pharmacological Properties
5.2. Molecular Biological Mechanisms of Bone Cells and the Surrounding Tissues
5.3. Processing Technology of Titanium Implants
5.4. Clinical Application of Titanium Implants
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Ma, X.; Gao, Y.; Zhao, D.; Zhang, W.; Zhao, W.; Wu, M.; Cui, Y.; Li, Q.; Zhang, Z.; Ma, C. Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics. Nanomaterials 2022, 12, 47. https://doi.org/10.3390/nano12010047
Ma X, Gao Y, Zhao D, Zhang W, Zhao W, Wu M, Cui Y, Li Q, Zhang Z, Ma C. Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics. Nanomaterials. 2022; 12(1):47. https://doi.org/10.3390/nano12010047
Chicago/Turabian StyleMa, Xiao, Yun Gao, Duoyi Zhao, Weilin Zhang, Wei Zhao, Meng Wu, Yan Cui, Qin Li, Zhiyu Zhang, and Chengbin Ma. 2022. "Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics" Nanomaterials 12, no. 1: 47. https://doi.org/10.3390/nano12010047
APA StyleMa, X., Gao, Y., Zhao, D., Zhang, W., Zhao, W., Wu, M., Cui, Y., Li, Q., Zhang, Z., & Ma, C. (2022). Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics. Nanomaterials, 12(1), 47. https://doi.org/10.3390/nano12010047