Next Article in Journal
Ultrasonication-Assisted Green Synthesis and Physicochemical and Cytotoxic Activity Characterization of Protein-Based Nanoparticles from Moringa oleifera Seeds
Previous Article in Journal
Enhancing the Stability and Mobility of TFTs via Indium–Tungsten Oxide and Zinc Oxide Engineered Heterojunction Channels Annealed in Oxygen Ambient
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nanomaterials
Volume 14
Issue 15
10.3390/nano14151253
nanomaterials-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite thumb_up
...
Endorse textsms
...
Comment
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Biological Nano-Agrochemicals for Crop Production as an Emerging Way to Address Heat and Associated Stresses

by
József Prokisch
1,
Aya Ferroudj
1,
Safa Labidi
1,
Hassan El-Ramady
1,2 and
Eric C. Brevik
3,*
1
Nanofood Laboratory, Department of Animal Husbandry, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, 138 Böszörményi Street, 4032 Debrecen, Hungary
2
Soil and Water Department, Faculty of Agriculture, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt
3
College of Agricultural, Life, and Physical Sciences, Southern Illinois University, Carbondale, IL 62901, USA
*
Author to whom correspondence should be addressed.
Nanomaterials 2024, 14(15), 1253; https://doi.org/10.3390/nano14151253 (registering DOI)
Submission received: 16 June 2024 / Revised: 21 July 2024 / Accepted: 24 July 2024 / Published: 26 July 2024
(This article belongs to the Section Environmental Nanoscience and Nanotechnology)
Browse Figures
Versions Notes

Abstract

:
Climate change is a global problem facing all aspects of the agricultural sector. Heat stress due to increasing atmospheric temperature is one of the most common climate change impacts on agriculture. Heat stress has direct effects on crop production, along with indirect effects through associated problems such as drought, salinity, and pathogenic stresses. Approaches reported to be effective to mitigate heat stress include nano-management. Nano-agrochemicals such as nanofertilizers and nanopesticides are emerging approaches that have shown promise against heat stress, particularly biogenic nano-sources. Nanomaterials are favorable for crop production due to their low toxicity and eco-friendly action. This review focuses on the different stresses associated with heat stress and their impacts on crop production. Nano-management of crops under heat stress, including the application of biogenic nanofertilizers and nanopesticides, are discussed. The potential and limitations of these biogenic nano-agrochemicals are reviewed. Potential nanotoxicity problems need more investigation at the local, national, and global levels, as well as additional studies into biogenic nano-agrochemicals and their effects on soil, plant, and microbial properties and processes.

1. Introduction

Global climate change represents a serious threat to crop production [1]. Climate change can subject crops to stresses including heat, flooding, salinity, drought, and soil nutrient deficiencies [2]. These stresses can reduce crop productivity by up to 50%, depending on the type of stress [3]. Stresses may occur individually [4] or in combination [2,5,6] that simultaneously or sequentially impact crop yield and the overall health of an agroecosystem [7]. How crops balance their growth and respond to adverse environments or stresses have been reported in several studies [8], which include abiotic stresses [9] such as drought [10], salinity [11], flooding [12], heat [13], heavy metals [14], and ozone [15], as well as biotic stresses [16].
Crop production requires considerable management to alleviate stresses. This often includes agrochemicals such as fertilizers and pesticides. The application of nano-enabled agrochemicals in the agricultural sector has gained considerable attention due to the lack of sustainability of many modern agricultural practices [17]. Reports on the use of nano-agrochemicals to counter biotic and abiotic stresses have included the documentation of smart nano-agrochemicals [18], nanotoxicity on non-target aquatic species [19], influence on the plant-beneficial microbiome [17], enhancing stress tolerance [20], nanopesticide formulations [21], nano-priming [22], drought stress [23], and environmental nano-preservation [24]. Among nano-agrochemical forms, biological nano-formulations are considered the most desirable approach under stressful conditions [20,23,25,26,27,28]. The biological nanomaterials have many promising benefits for the sustainable production of crops due to their high efficiency and low toxicity [20] in alleviating plant abiotic and biotic stresses (through nanopesticides) and improving the delivery of targeted nutrients by nanofertilizers [27].
Heat stress is one of the biggest crop production challenges related to global climate change. Heat stress is not just a challenge on its own but is also associated with other stresses that may link to drought [29,30,31], salinity [32,33,34,35], and biotic stress [36]. The main impact of heat stress is in the production of reactive oxygen species (ROS) that cause oxidative damage to plant cell organelles and their functions [37]. Irreversible injuries can reduce the productivity of crops, causing yield loss and a reduction in food quality, even under short exposure to heat stress [37].
Therefore, this review is an attempt to emphasize the synergistic role of biological nano-agrochemicals in the mitigation of heat stress and other associated stresses during crop production. The promising mitigating effects of biogenic nanofertilizers and nanopesticides on heat stress will be highlighted. Nano-management of heat stress and suggested strategies will be reported as well.

2. Nano-Agrochemicals and Crop Production

Nano-agrochemicals can be defined as nanomaterials and/or formulations that are designed and controlled at the nanoscale for agronomic purposes (Figure 1). These compounds have great potential to revolutionize farming practices by promoting the efficiency of agronomic practices using properties of these NMs, such as controlled nutrient release, high use efficiency, high surface area, and reduced ecological risks [17]. Many benefits can be listed for the nano-agrochemicals, such as their eco-friendly nature, reduced loss/volatilization rate, high uptake by plants, reduced applied dosage, high use efficiency and bioavailability, controlled delivery with reduced resistance, and minimal effect on non-targeted organisms. The advantages of nano-agrochemicals have been confirmed for many different crops to enhance their productivity under stressful or/and non-stressful conditions, as reported in the following sections of this review. On the other hand, several ecological risks could occur due to the application of nano-agrochemicals. These risks could result in nanotoxicity to the agroecosystem, including phytotoxicity and nanotoxicity to the soil system, loss of biodiversity in both soil and water, and toxicity to farm animals and humans.

3. Stresses Associated with Heat Stress

Crops face many stresses that can be classified into four groups: (1) soil, (2) anthropogenic, (3) climate, and (4) biotic stresses (Figure 2). The first three are often referred to as abiotic stresses. Specific stresses related to soil, including abiotic stresses such as pH [38], salinity [39], alkalinity [40], waterlogging [41], compaction [42,43], nutrient deficiencies [44,45], soil pollution [46], and soil nano-pollution [47], as well as biotic stresses such as soil-borne plant pathogens [48] and parasites [49], have been investigated. Anthropogenic pollutants that can stress plants include particles from combustion [50], pesticides [51], heavy metals [52], nano-microplastics [53], persistent organic pollutants [54], and airborne nano-pollution [55]. Climatic stresses involve factors such as cold [56,57], drought [23], flooding [12], ozone [15], heat [4], ultra-violet light exposure [58], and wind [59]. Biotic stresses include grazing [60], insects [61], bacterial [62], fungal [16], and viral pathogens [63]. These stresses may occur individually or in combination, such as heat and salinity [34,64]; waterlogging and drought [65]; heat and drought [30,66]; heat and pathogen stress [67]; heat and nutrient stress [68]; salinity, drought, and waterlogging stress [69]; or heat, drought, and ozone stress [70].
Heat stress can cause adverse impacts on plants during all growth stages, starting from germination through reproductive development and maturation. Under climate change, heat stress (when crops are subjected to temperatures > 35 °C) or extreme heat waves represent a serious threat to crops and their physiology [71], as well as on food, water, and energy security [72]. Temperature stress types can be classified into two main groups: heat stress (>35 °C) and cold stress, which may include chilling injury (15–0 °C) and freezing injury (<0 °C). Many changes in plant functional processes occur under higher temperatures, which negatively affect crop productivity. The reproductive stage is greatly hampered by heat stress in almost all plants [37]. This section explores examples of combined stresses that are associated with heat stress.
Nanomaterials 14 01253 g002
Figure 2. The main sources of stress on cultivated plants in single and combined forms. Heat stress can be found in association with many other stresses, such as drought, salinity, flooding, and nutrient deficiencies. Sources: [7,69,73].
Figure 2. The main sources of stress on cultivated plants in single and combined forms. Heat stress can be found in association with many other stresses, such as drought, salinity, flooding, and nutrient deficiencies. Sources: [7,69,73].
Nanomaterials 14 01253 g002

3.1. Heat and Drought Stress

The main responses of cultivated plants to heat stress involves morphological, biochemical, physiological, and molecular attributes and processes (Figure 3). Heat stress can lead to damage at any plant growth stage, with a corresponding reduced crop yield. This requires urgent and timely management, as possible strategies to protect crops from heat stress include avoiding this stress as the first option. Subsequent strategies include how to create heat tolerance in plants and adaptations to address the heat stress (Figure 4).
Many studies have addressed strategies to deal with heat stress, e.g., [37,74,75,76,77]. Plants can evolve complex acclimation mechanisms to address stresses that can be tailored by stressed plants to be more suitable under stress combinations [78]. Therefore, plant responses to combined stresses cannot be easily predicted based on studies that investigated stresses individually [79]. Plant survival and growth under two or more stresses that occur simultaneously may be improved or reduced as compared to each stress individually, although most combined stresses have additive negative impacts [2]. Understanding the tolerance mechanisms of crops and how they interact under the variable environmental conditions driven by climate change is important to maintain the stability of crop yields under field conditions [2].
Due to the increasing mean global temperatures, combined heat and drought stresses are becoming more common and negatively affect the global farming system [2]. Combined drought and heat stress can cause significant reductions in crop yields, including tomato [80], wheat [81,82], maize [83], rice [84], soybean [85], chickpea [86], and potato [87]. Crop responses to combined heat and drought stress mainly depend on the presence of antistressors (i.e., phytohormones and amendments), along with the tolerance of such crops to these stresses (Table 1).
Nanomaterials 14 01253 g003
Figure 3. The main responses of crops to heat stress. The main attributes effected by these responses are morphological, biochemical, physiological, and molecular (Sources: [37,74,75,76,77]). The plant images were downloaded from https://www.flaticon.com/free-icon/plant_4147953 accessed on 3 March 2024. Abbreviations: reactive oxygen species (ROS), nitrate reductase (NR), glutamine oxoglutarate aminotransferase (GOGAT), glutamate dehydrogenase (GDH), glutamine synthetase (GS).
Figure 3. The main responses of crops to heat stress. The main attributes effected by these responses are morphological, biochemical, physiological, and molecular (Sources: [37,74,75,76,77]). The plant images were downloaded from https://www.flaticon.com/free-icon/plant_4147953 accessed on 3 March 2024. Abbreviations: reactive oxygen species (ROS), nitrate reductase (NR), glutamine oxoglutarate aminotransferase (GOGAT), glutamate dehydrogenase (GDH), glutamine synthetase (GS).
Nanomaterials 14 01253 g003
Nanomaterials 14 01253 g004
Figure 4. Possible strategies that crops can adopt against heat stress. These strategies include three broad options: avoiding the stress, tolerating the stress, and adapting to the stress. Sources: [9,37,74,75,77,88].
Figure 4. Possible strategies that crops can adopt against heat stress. These strategies include three broad options: avoiding the stress, tolerating the stress, and adapting to the stress. Sources: [9,37,74,75,77,88].
Nanomaterials 14 01253 g004
Table 1. Impacts of combined drought and heat stress on crops in the presence and absence of antistressors.
Table 1. Impacts of combined drought and heat stress on crops in the presence and absence of antistressors.
Plant SpeciesStress Conditions (Heat and Drought)Applied Antistressors (If Any)Main Findings Refs.
Tomato (Solanum lycopersicum L.) Drought (40%FC), heat stress (38 or 45 °C (8 or 6 h)Arbuscular mycorrhizal fungi (AMF)AMF induce alterations in phytohormones and modulate aquaporin expression under stress[80]
Soybean (Glycine max L.)Heat (40 °C) and drought (30% reduction in pot weight) for 9 daysJasmonic acid (JA) at 0, 50, 100 and 250 µM for 8 daysJA-priming protected seedling growth by improving the photosynthetic efficiency and potentiated antioxidant defense responses to alleviate oxidative stress[85]
Potato (Solanum tuberosum L.) Drought (PEG 8000; 10%) and heat (35 °C) for 15 daysTransgenic potato plants with no added antistressorsThese plants minimized oxidative stress by activating antioxidants (Cu-Zn-SOD, Fe-SOD, CAT) and accumulation of osmo-protectants [87]
Wheat (Triticum aestivum L.) Drought (no watering of plants), heat (29 °C) for 5 daysNo added antistressors, grown in two Biotron climate chambersNegative impacts on biomass and yield, positive impact on most gluten parameters[81]
Wheat (Triticum aestivum L.)Heat (36 °C), drought (45–55% of soil water holding capacity)No added antistressors, grown in artificial growth chambersCombined stress reduced photosynthetic pigments and rate; the activities of SOD, POD, CAT, and GR. Plants increased osmo-regulation by forming soluble protein and sugar, proline [89]
Cotton (Gossypium hirsutum L.)Heat (37 °C), drought expressed as 25% water replacement No added antistressors, grown for 4 weeks in growth chamberCo-overexpression of RCA and AVP1 support transgenic cotton by increasing net photo-synthetic rate and seed fiber yield[90]
Durum wheat (Triticum turgidum L.) Heat (31–36 °C), drought (180 mm of irrigation water reduced from 500 mm for full irrigation)No added antistressors, field study using drip irrigationStudied glutenin fractions and the γ-gliadins were significantly reduced under stress, while β-gliadins were increased[91]
Chickpea (Cicer arietinum L.) Drought stress by withholding water for 3 days; heat at 32, 35 and 38 °C for 12, 6 and 2 h, resp.No added antistressors, growth chamber; pots containing sandDrought priming and consequent heat stress confirmed the role of heat shock proteins and heat shock factors and related tolerant gene families in studied plants[86]
Wheat (Triticum aestivum L.)Drought (50–55% field capacity for 8 days), heat stress (36 °C) for 3 daysNo added antistressors, pots contained sand, soil, and farm yard manureDuring vegetative growth drought priming activated plant defenses, antioxidative action; induced thermo-tolerance calmodulin, polyamine and glutathione synthesis genes[92]
Winter wheat (Triticum aestivum L.)Heat stress (38 °C), drought (water at permanent wilting point) for 14 daysNo added antistressors, potted soils in a growth chamberStress reduces water availability on leaf gas-exchange parameters (photosynthesis, transpiration, and WUE) during stem extension stage inducing changes in grain yield [93]
Abbreviations: polyethylene glycol (PEG), catalase activity (CAT), superoxide dismutase (SOD), peroxidase (POD), glutathione reductase (GR), Rubisco activase (RCA), Arabidopsis vacuolar H+-pyrophosphatase gene (AVP1), and water use efficiency (WUE).
Several reports on metabolic and physiological processes under combined heat and drought stress have been published. These reports focused on many issues, including the strong inhibiting role of both drought and heat stress in reducing the partitioning of carbon assimilates to the roots, increasing oxidative stress and the antioxidant capacity [2]. The role of signaling lipids was also reported, including sphingolipids, oxylipins, phosphatidic acid, phosphor-inositides, lyso-phospholipids, and N-acylethanolamines, for mediating the combined drought and heat stress [29]. The response of grass pea and its wild relatives to combined heat and drought stress was discussed by Aloui et al. [94], whereas the response of wild relatives of rapeseed mustard was reported by Kashyap et al. [95]. The complex plant response to heat and drought stress under climate change was reported by Puppala et al. [96] and Sato et al. [31].

3.2. Heat and Salinity Stress

Soil salinization has become common in many areas all over the world under increasing atmospheric temperatures, especially the arid and semi-arid regions [32]. Arid and semi-arid areas were estimated to be 33% of global irrigated arable soils suffering from salinization [97]. The main contributors to salinity stress (saline soil and irrigation water) may trigger ionic, oxidative, and osmotic stresses, which require the production of plant-protective compounds or enzymic antioxidants against ROS and osmo-protectant metabolites for regulation of the osmotic potential of plants [97]. High temperatures in arid zones can accelerate the formation of soil salinization, leading to more stress on crops [98]. It is expected that climate change will increase the salinization of soils under heat waves that vary in duration, intensity, and frequency [74,99,100,101]. Thus, the management of both heat and salinity stress in cropping systems will become increasingly important. This may involve agricultural practices like grafting [99], heat pre-treatment for seeds [102], seed nano-priming [103,104], or biotechnology approaches [105]. The application of antistressors has been used to mitigate combined heat and salinity stresses in crops (Table 2). The most promising nanomaterial antistressors used against combined heat and salinity stress in crops include nano-selenium [64], nano-silica [102], and silicon [106]. Phytohormones such as salicylic acid [33,107] and gibberellic acid [98] have also been reported as antistressors to support crop production under combined heat and salinity stress. The mechanisms of such combined stresses and its mitigation by plants still need more investigation.

3.3. Heat and Pathogenic Stress

Higher temperatures may support the growth and spread of phytopathogens. In a review on the effects of heat stress on plant–pathogen interactions, Desaint et al. [113] discussed the key features of combined heat and pathogenic stress (Figure 5). Under combined stress, the response of plants cannot be predicted from the evaluation of individual applied stresses [114]. Photosynthesis and carbon metabolism are expected to downregulate under individual and combined stresses through the activation of transcription factors (TFs). Under heat stress, plant susceptibility may increase due to the inhibition of plant defenses [113]. The negative effects of heat stress on plant resistances are not restricted to specific species of pathogens or plants and their related lifestyles. Generally, increased temperature negatively affects all types of resistance responses (i.e., pathogen-triggered immunity, effector-triggered immunity, and quantitative-disease resistance), although cases of immune response inhibition mainly concern effector-triggered immunity [113]. Studying the combined stress of heat and pathogens still needs more investigation that takes into account the complexity of the natural interactions among plants, a wide variety of pathogens (i.e., plant pathobiota), and the soil microbial community.
Many studies have reported negative impacts of heat and pathogens on crop production, such as grapes [115], wheat [116], chickpea [117], and peas [118]. On the other hand, the benefits of heat stress were evaluated as heat pre-treatment (priming) to support plant production under phytopathogen stress. This approach was confirmed for many plants, such as barley using brassinosteroids [119], soybean under nano-selenium application [120], Arabidopsis seedlings using Bacillus cereus for plant growth promotion [121], French bean (Phaseolus vulgaris) using serine peptidases [122], and barley (Hordeum vulgare L.) using heat shock [123]. Other reviews on this topic have addressed plant nutrient relations under heat stress [76], heat stress in a variety of crops [124,125,126,127], maize and heat stress [128], and rice breeding under heat stress [129].
Nanomaterials 14 01253 g005
Figure 5. The mechanisms plants use to combat pathogens under heat stress. Adapted from [113].
Figure 5. The mechanisms plants use to combat pathogens under heat stress. Adapted from [113].
Nanomaterials 14 01253 g005

4. Biogenic Nano-Agrochemicals

There are many groups of nano-agrochemicals, which can be classified into nanofertilizers, nano-biofertilizers, and nanopesticides, in which NPs are considered active ingredients in different forms, such as nano- and bioencapsulation, nanodelivery systems, etc. Nanopesticides may include nano-fungicides, nano-herbicides, nano-insecticides, nano-bactericides, and nano-nematicides. These nano-compounds also allow the targeted delivery of nutrients for crop productivity [130]. Nano-agrochemicals are considered sustainable alternatives to traditional agrochemicals, especially the biological and/or green forms of nano-agrochemicals [131,132]. The term biogenic nano-agrochemicals comes from using biological organisms (bacteria, fungi, algae, etc.); plant extracts (leaves, flowers, stems, etc.); or agro-industrial biowastes to produce nano-agrochemicals. The main function of these molecules is to act as natural capping, reducing, and stabilizing agents, which is critical to making NMs useful for agricultural purposes [133]. As compared to the physical and chemical approaches of making NMs, the biogenic techniques are economically viable, eco-friendly, and highly efficient. Physical and chemical synthesis of NMs have many problems. They are expensive, produce toxic byproducts, and require high energy input and axillary reagents [133]. Thus, the biological or green synthetic techniques to make NMs are considered a sustainable approach [134]. The process of preparing NMs using biogenic methods has been reported for many applications, such as biomedical applications [135]; nano-biofortification [136]; and using nanometals such as selenium [45], silver [137,138], iron [136], TiO2 [139], zinc/zinc oxide [140,141], and copper oxide [142] to address a variety of agronomic issues. The utilization of nanopesticides and nanofertilizers has been considered a solution for global food security and sustainable agricultural development [21,143]. Although nano-enabled agrochemicals can mitigate the toxicity of heavy metals [144], their ecological risks, fate, mobility, and ecotoxicology are still unknown, with the potential for significant threat to human health [145].

5. Nano-Management of Crop Production under Heat Stress

Due to climate change, plant growth and productivity face many adverse effects under higher temperatures, leading to heat stress [146]. Heat stress can alter all plant attributes, including the morphological, biochemical, and physiological processes in plants, leading to a significant reduction in plant growth and crop production [147]. This reduction is a result of the accumulation of reactive oxygen species (ROS), H2O2, and malondialdehyde (MDA). The most sensitive plant growth stage to heat stress is the reproductive stage, where heat stress causes a loss in flower buds and seed yield, along with chlorophyll degradation, photosystem II disruption, and inhibition of the photosynthetic process [146]. Management of heat stress in crops can be achieved though approaches such as mulching [148]; nutrient management [64]; the application of protectants including salicylic acid [149], trehalose [150], melatonin [35], and β-sitosterol and biochar [151]; molecular breeding strategies [4]; bacterial seed treatment [75]; and nano-management [64,146,152,153].

5.1. Biogenic Nanofertilizers under Heat Stress

The growing global population has led to an increase in food demand. Modern approaches emphasize increased fertilizer utilization for higher crop production. However, chemical fertilizers have low use efficiency and cause many environmental problems (Table 3). Nanofertilizers are a promising approach when they are applied at the right time in the correct dose and form. Some nanofertilizers show more promise than others, with biological nanofertilizers and slow-release nanofertilizers being particularly promising. In general, nanofertilizers (particle sizes 1–100 nm) have higher surface areas, higher fertilization efficiency, lower loss rates, higher microbial activity, a timely and balanced nutrient supply, and lower costs compared to traditional chemical fertilizers [154]. Problems associated with traditional chemical fertilizers include eutrophication, soil quality deterioration, groundwater and air pollution, and a diminished soil macro- and micronutrient supply capacity [155,156,157]. Biological nanofertilizers are preferable compared to other nanofertilizers due to lower cost, toxicity, and high safety levels, leading to sustainable farming [158].
Table 3. A comparison of nanofertilizers with traditional chemical fertilizers.
Table 3. A comparison of nanofertilizers with traditional chemical fertilizers.
Comparison ItemChemical FertilizersNanofertilizers
Definition All fertilizers that are synthetized from chemical materials in factories using industrial processesFertilizers at a nanoscale that can supply plants with nutrients, may include chemical or biological forms
Main methods of synthesisMainly from industrial chemical and physical methods Physical (e.g., evaporation, laser ablation, and sputtering); chemical (e.g., vapor deposition, chemical reduction, and sol–gel synthesis); biological/green synthesis (microbes-mediated and biomimetic synthesis); recycling methods (e.g., mechanical attrition and electrochemical synthesis); and others
Main methods of applicationSoil application, foliar spraying (phyllo-sphere), and seed primingSoil application (rhizosphere), foliar spraying (phyllo-sphere), and seed priming
Types of fertilizersMainly depends on the type of nutrient in the synthetized fertilizer, such as N, P, K, or others. Often have high purity and supply only the nutrients they were designed toNanoscale additives (nanodelivery of nutrients as particles or emulsions), nanoscale fertilizers (controlled release of nano-nutrients by encapsulation), and nanoscale coatings (incorporated ingredients in the matrix of organic biochemical polymers, serving as carriers)
Types of composite fertilizersThere are single and combined fertilizers along with composite fertilizers like (19:19:19, N:P:K)Hydroxyapatite, hydrogel, chitosan, graphene or carbon, zeolite, etc.
Factors that control nutrient-release, movement, translocation, and uptake by plants Factors related to fertilizer, cultivated plants, soil properties and other environmental factors Factors related to nano-nutrients (dose, size of NPs, surface, type, etc.); growing conditions (moisture, temperature, pH, salinity, etc.); plant species (roots, growing stage, etc.); and growth media (rhizosphere, pH, and microbial activity)
Advantages of such fertilizersHigh solubility and high uptake rate by cultivated plants, relatively inexpensive supply of nutrientsHigher nutrient use efficiency, timely and balanced nutrient supply, improved edaphic features, higher microbial activity and soil amelioration, lower loss rate, production cost, vol/wt. other than the traditional due to their tiny size and larger surface area, promote precision farming, water holding capacity
Main proposed problems Soil quality deterioration, eutrophication, groundwater pollution, and air pollutionNanotoxicity to plants, microbes, food chain, water, air, and human health
Main loss pathways Loss by leaching, evaporation, and surface runoffLoss by evaporation, drifting, surface runoff, hydrolysis, and photolytic degradation of nutrients
Sources: [73,111,154,155,156,157].
Many studies have focused on biogenic nanofertilizers and discussed nutrients such as CuO- and ZnO-NPs [159], Zn-NPs/ZnO-NPs [140,160], Si-NPs [161], phosphorous NPs [162], silver and iron NPs [163], MgO-NPs [164], and CuO-NPs [165]. Many of these reports have focused on sustainable agriculture [132,158,166], but few have addressed heat stress (Table 4). The impact of these nanofertilizers on heat stress depends on the synthesis process, size of the NPs, and plant species, which control the plant tolerance to heat stress through the action of osmo-protectants, phytohormones, and signal molecules [167]. These plant-produced molecules are more bioavailable and effective after applying NMs or NPs, as they facilitate the delivery of plant-produced molecules to their action sites [168]. Foliar application of many nano-based nutrients (e.g., SiO2-NPs, Se-NPs, ZnO-NPs, and CuO-NPs) has been reported to be effective against heat stress (Table 4). These NPs can enhance plant growth and performance by supporting the plant defense system through increased antioxidant enzyme activity, accumulation of proline, gas exchange, photosynthetic apparatus efficiency, etc.
The mechanisms underlying the NP-mediated regulation of stress responses may differ from one NP to another; there is a need to understand the transcriptomics in general [167], along with the plant-associated microbiomes and engineering [17]. For example, CeO2-NPs as nano-enzymes reduced heat damage to photosystems by scavenging ROS in plant chloroplasts and increased the quantum yield in photosystem II, carbon assimilation rate, and rubisco carboxylation by 19, 67, and 61%, respectively, compared to the control [176]. There is a need for more research on biogenic nanofertilization that investigates different nanofertilizer and crop combinations.
Treating plants under heat stress with NPs can reduce such stress by triggering one or more molecular reactions through the production of enzymes and proteins, transcription factors, and gene controls that support plant survival [22]. For example, Si applied at 1.66 mM on wheat seedlings under heat stress (45 °C, 4 h) stimulated the overexpression of genes for the aquaporins TaPIP1 (Triticum aestivum plasma membrane intrinsic protein) and TaNIP2 (Triticum aestivum nodulin 26-like intrinsic protein) in wheat but not Si-NPs [177]. On the other hand, the study of the molecular impacts of ZnO-NPs on Arabidopsis thaliana seedlings during heat stress (37 °C) showed TGS (transcriptional gene silencing) in aerial leafy tissues and the improved alleviation of TGS-GUS (-glucuronidase) genes [172]. The most significant impact of applied NPs was the upregulation of genes encoding for the large and small subunits of RUBISCO, chlorophyll a/b-binding proteins, and phosphoenolpyruvate carboxylase (PEPC), which, in turn, caused an increase in photosynthesis, altered the energy metabolism, and decreased the H2O2 concentration [178,179].

5.2. Biogenic Nanopesticides for Crop Protection

There are many kinds of pesticides, depending on their nature (plant-derived or mineral oil-based) or application (e.g., insecticides, herbicides, fungicides, algicides, nematicides, bactericides, rodenticides, etc.). Traditional pesticides may cause several environmental problems due to runoff and chemical processes like hydrolysis, biodegradation, bioaccumulation, and photodegradation [180]. Thus, the extensive use of traditional pesticides has led to adverse impacts on the agroecosystem and human health [181]. Nanopesticides can be used for crop disease and pest management and come in different formulations, such as nanocarrier-based pesticides and nano-emulsion-based surfactants incorporated with metal or metal oxide-NPs as active ingredients (AI) [182]. Nanopesticides represent a promising solution with exceptional performance advantages over conventional pesticides [130]. These benefits include reduced environmental pollution risks; improved chemical stability, efficiency, and target delivery; and good biocompatibility as compared to conventional pesticides [180] (Figure 6).
To avoid the problems of traditional pesticides, alternatives are needed, like bio-based pesticides that are derived from organic sources, including microbes, animals, plants, and fungi. These bio-based pesticides are safer and more eco-friendly than traditional chemical pesticides. Along with bio-pesticides, nanopesticides are important alternatives that include metal/metalloid-based nanopesticides (e.g., Ag, Se, CuO, TiO2, SiO2, and ZnO) and nanocarrier-based pesticides composed of many materials, such as lipids, polymers, and proteins [130]. Other forms include nano-silica pesticides [183], nano-emulsion-based pesticides [184], polymer-based nanopesticides [185], chitosan-based nanopesticides [186], and nano-capsule-based pesticides [187]. There are metallic oxide-NPs that have fungicidal and antimicrobial properties that make them useful against many phytopathogens. These include nano-TiO2, nano-ZnO, and nano-Fe2O3 [188,189]. Many nanomaterials have been used to control phytopathogens (bacterial, fungal, and viral; Table 5), along with the biogenic approach for sustainable agriculture [133].
Many different formulations of nanopesticides have been produced through biogenic or chemical approaches using metals/metalloids such as Ag, SiO2, CuO, and ZnO, along with nanocomposites like SiO2/Ag nanocomposite or chitosan [187,190,191,192]. As far as we know, there are no studies on the direct impact of applied geogenic nanopesticides under heat stress on cultivated plants. Investigations have included studies on the thermo-responsiveness of nanopesticides [193,194]; controlled release by nanopesticides [195]; and factors that control the release of active ingredients from nanopesticides under heat stress, along with other factors, including pH, light, redox status, enzymes [129], and the release of nanopesticides at high temperatures [196]. High temperatures may cause an increase in the level of several phytopathogens and microbial disease outbreaks, particularly under higher humidity, because temperature directly controls the reproduction and metabolism of microbes [197]. Temperature not only controls phytopathogen invasion but also potentially the extent of plant host damage during infection through its impact on plant pathogen enzymatic activities and toxin production [198]. Thus, the study of biogenic nanopesticide performance in crops under heat stress still needs more investigation.
Table 5. Impacts of nanopesticides on crop production and their anti-pest activity.
Table 5. Impacts of nanopesticides on crop production and their anti-pest activity.
Plant Species or Culture UsedNano-Based Pesticide (Applied Dose and Size)Pathogen StudiedMain EffectRefs.
Common Bean (Phaseolus vulgaris L.)Nano-Se + SiO2, 50 ppm of eachFungal pathogen (Alternaria alternata L.) Effective alternatives to traditional fungicide to control A. alternata in common bean[199]
Pine (Pinus thunbergii Parl.)Nano-Cu-BTC (10 ppm)Pine wilt nematode (Bursaphelenchus xylophilus)Effectively controlled Japanese pine sawyer vector insect by delivering avermectin absorbed by the insect larvae [200]
Lentil (Lens culinaris medik.)ZnO-NPs (100 ppm) (<100 nm)Bacterial pathogen (Xanthomonas axonopodis pv. phaseoli)Reduced blight, wilt, nematode multiplication, and leaf spot disease severity indices and increase plant growth[201]
Rice (Oryza sativa L.)ZnO-NPs (4, 8, and 16 ppm) (48.2 nm)Bacterial pathogen (Xanthomonas oryzae pv. oryzae)Effective anti-microbial agents against bacterial leaf blight of rice [202]
In vitro assay (nutrient agar medium)Biogenic Ag-NPs (100 ppm) (55 nm)Bacterial pathogen (Ralstonia solanacearum)Inhibited the bacterial activities by damaging the pathogen’s cell membrane[203]
In vitro assay (nutrient agar medium)Green Ag-NPs (10 ppm) (from 24.5 to 43.1 nm)Bacterial pathogen (Ralstonia solanacearum)An effective eco-friendly anti-bacterial agent inhibited R. solanacearum up to 80%[204]
In vitro assay (nutrient broth media)Green Ag-NPs (78 to 500 ppm) (from 23 to 63 nm)Bacterial pathogen (Ralstonia solanacearum)Effective alternative bacterial agent to control tomato wilt [205]
In vitro assay (nutrient agar medium)Biogenic SiO2/Ag nanocompositeBacterial pathogen (Ralstonia solanacearum)Effective and eco-friendly antibacterial agent, embedded in mesoporous nano-SiO2, avoids aggregated Ag-NPs[206]
In vitro assay (nutrient agar medium)Biogenic Ag-NPs (100 ppm) (55 nm)Fungal pathogen (Fusarium oxysporum)Mycelial growth of fungi was reduced up to 40–50% [203]
In vitro assay (poisoned food technique)ZnO-NPs (10, 100, and 1000 ppm) (<50 nm)Fungal pathogen (Alternaria alternata L.)Nano-fungicide had higher efficacy than bulk form (ZnSO4)[207]
In vitro assay (using broth culture)Green ZnO-NPs (25, 50, 100, and 140 ppm) (30–40 nm)Fungal pathogen (Fusarium graminearum L.)Reducing deoxynivalenol and zearalenone controlled growth and mycotoxins[208]
In vitro assay (poison food technique)ZnO-NPs (100 and 800 ppm) (20–60 nm)Fungal pathogen (Fusarium moniliforme)Antimycotic potential of NPs inhibited hyphal growth, depending on particle size[209]
Tomato (Lycopersicon esculentum L.)Silica-NPs (100, 200, 300 and 400 ppm) (10.7 nm)Fungal pathogen (Alternaria solani)Reduced disease severity as an eco-friendly and safe alternative to chemical fungicides[210]
Table grape (Vitis vinifera L.)Chitosan silica nanocompositesFungal pathogen (Botrytis cinerea)Reduced fungal growth 100% by inducing enzymatic activity and gene expression levels[211]
Tobacco (Nicotiana benthamiana L.)ZnO-NPs (100 ppm), (18 nm)Viral pathogen (tobacco mosaic virus)Marked suppression of viral invasion in the inoculated leaves by increasing SA and ABA phytohormone levels[212]
Abbreviations: Polymers of copper and trimesic acid (Cu-BTC), salicylic acid (SA), and abscisic acid (ABA).

6. Potential and Limitations

As mentioned before, the biogenic approach to produce nano-agrochemicals has several benefits compared to chemical and physical approaches. This includes the low toxicity and risk to the agro-environment, along with the low cost of biogenic products. Many ecological risks do exist under the excessive application of nano-agrochemicals, with the level of risk primarily depending on the size, shape, and biodegradability of the NMs [6]. Several studies have addressed this concern, including Chaud et al. [213], Grillo et al. [214], Maity et al. [215], Mubeen et al. [21], and Victoria et al. [180]. Ecotoxicological risks can be reduced by applying nano-agrochemicals at the right time in the correct dose to suitable crops. Environmental conditions (e.g., temperature, light, humidity, and the microbial community) control the biodegradation of such nanomaterials, their persistence, and their toxicity risks. Several questions need to be addressed as regards nanomaterial use in the agricultural setting:
-
Are phytopathogens able to sense plant heat stress, and, if so, are they involved in virulence?
-
How does heat stress affect microbial virulence at the metabolic and transcriptional levels?
-
How can we engineer plants to be resistant to heat stress using biogenic nano-agrochemicals?
-
How do plants adapt to heat stress, and how can biogenic nano-agrochemicals support this adaptation?
-
To what extent can we produce biogenic nano-agrochemicals at the industrial scale?
-
To what extent can we apply biogenic nano-agrochemicals against heat stress in the greenhouse and at the field level?
-
What is the biocompatibility of biogenic nano-agrochemicals?
-
What are the key functional groups in nanomaterials for assessing their nanotoxicity?
-
Do biogenic nano-agrochemicals have a negative impact on non-target organisms under heat stress?
-
What are the expected nanotoxicity and risks of biogenic agrochemicals over the long term in agro-ecosystems in the presence and absence of heat stress?
-
To what extent is a multidisciplinary approach needed to evaluate the impact of biogenic nano-agrochemicals?

7. Conclusions

Global climate change is a threat to food production. Higher temperatures are a common feature of climate change. Heat stress threatens food security as an individual stress and in association with other stresses like drought, salinity, and pathogenic stress. This leads to many problems for crop production. The use of nano-agrochemicals is a promising approach to mitigate heat stress and associated stresses, with a focus on nanofertilizers and nanopesticides. Compared to traditional chemical approaches, the biogenic nano-strategy is an emerging potential solution for sustainable agricultural production. These biogenic nano-agrochemicals are preferable due to their cost-effectiveness, high bioavailability, biocompatibility, and high potential to synthesize their NMs. Although biogenic nano-agrochemicals are superior alternatives to traditional agrochemicals for the control of phytopathogens and to supply nutrients, the ecological safety aspects of NM use in agriculture still need more investigation.

Author Contributions

Conceptualization, H.E.-R. and J.P.; methodology A.F. and S.L.; software, A.F., S.L. and J.P.; validation, H.E.-R. and E.C.B.; formal analysis, H.E.-R. and E.C.B.; investigation, H.E.-R., J.P., A.F. and S.L.; resources, H.E.-R., J.P., A.F. and S.L.; data curation, H.E.-R. and J.P.; writing—original draft preparation, H.E.-R. and E.C.B.; writing—review and editing, H.E.-R. and E.C.B.; visualization, H.E.-R. and J.P.; supervision, J.P.; project administration, J.P.; funding acquisition J.P. All authors have read and agreed to the published version of the manuscript.

Funding

This research was supported by the Stipendium Hungaricum Scholarship Program.

Data Availability Statement

No new data were created in this study.

Acknowledgments

All authors thank their institutions for their support.

Conflicts of Interest

The authors declare no conflicts of interest.

References

  1. Brevik, E. The Potential Impact of Climate Change on Soil Properties and Processes and Corresponding Influence on Food Security. Agriculture 2013, 3, 398–417. [Google Scholar] [CrossRef]
  2. Sánchez-Bermúdez, M.; Del Pozo, J.C.; Pernas, M. Effects of Combined Abiotic Stresses Related to Climate Change on Root Growth in Crops. Front. Plant Sci. 2022, 13, 918537. [Google Scholar] [CrossRef] [PubMed]
  3. Gebre, M.G.; Rajcan, I.; Earl, H.J. Genetic Variation for Effects of Drought Stress on Yield Formation Traits among Commercial Soybean [Glycine max (L.) Merr.] Cultivars Adapted to Ontario, Canada. Front. Plant Sci. 2022, 13, 1020944. [Google Scholar] [CrossRef] [PubMed]
  4. Kan, Y.; Mu, X.-R.; Gao, J.; Lin, H.-X.; Lin, Y. The Molecular Basis of Heat Stress Responses in Plants. Mol. Plant 2023, 16, 1612–1634. [Google Scholar] [CrossRef] [PubMed]
  5. Ndlovu, E.; Van Staden, J.; Maphosa, M. Morpho-Physiological Effects of Moisture, Heat and Combined Stresses on Sorghum Bicolor [Moench (L.)] and Its Acclimation Mechanisms. Plant Stress 2021, 2, 100018. [Google Scholar] [CrossRef]
  6. Ali, S.; Tyagi, A.; Mir, R.A.; Rather, I.A.; Anwar, Y.; Mahmoudi, H. Plant Beneficial Microbiome a Boon for Improving Multiple Stress Tolerance in Plants. Front. Plant Sci. 2023, 14, 1266182. [Google Scholar] [CrossRef] [PubMed]
  7. Zandalinas, S.I.; Mittler, R. Plant Responses to Multifactorial Stress Combination. New Phytol. 2022, 234, 1161–1167. [Google Scholar] [CrossRef] [PubMed]
  8. Zhang, H.; Zhao, Y.; Zhu, J.-K. Thriving under Stress: How Plants Balance Growth and the Stress Response. Dev. Cell 2020, 55, 529–543. [Google Scholar] [CrossRef] [PubMed]
  9. Zhang, Y.; Xu, J.; Li, R.; Ge, Y.; Li, Y.; Li, R. Plants’ Response to Abiotic Stress: Mechanisms and Strategies. Int. J. Mol. Sci. 2023, 24, 10915. [Google Scholar] [CrossRef]
  10. Singh, A.; Pandey, H.; Pandey, S.; Lal, D.; Chauhan, D.; Aparna; Antre, S.H.; Kumar, A. Drought Stress in Maize: Stress Perception to Molecular Response and Strategies for Its Improvement. Funct. Integr. Genom. 2023, 23, 296. [Google Scholar] [CrossRef]
  11. Hasanuzzaman, M.; Fujita, M. Plant Responses and Tolerance to Salt Stress: Physiological and Molecular Interventions 2.0. Int. J. Mol. Sci. 2023, 24, 15740. [Google Scholar] [CrossRef]
  12. Renziehausen, T.; Frings, S.; Schmidt-Schippers, R. ‘Against All Floods’: Plant Adaptation to Flooding Stress and Combined Abiotic Stresses. Plant J. 2024, 117, 1836–1855. [Google Scholar] [CrossRef] [PubMed]
  13. Graci, S.; Barone, A. Tomato Plant Response to Heat Stress: A Focus on Candidate Genes for Yield-Related Traits. Front. Plant Sci. 2024, 14, 1245661. [Google Scholar] [CrossRef] [PubMed]
  14. Anjitha, K.S.; Sarath, N.G.; Sameena, P.P.; Janeeshma, E.; Shackira, A.M.; Puthur, J.T. Plant Response to Heavy Metal Stress Toxicity: The Role of Metabolomics and Other Omics Tools. Funct. Plant Biol. 2023, 50, 965–982. [Google Scholar] [CrossRef]
  15. Singh, A.A.; Ghosh, A.; Agrawal, M.; Agrawal, S.B. Secondary Metabolites Responses of Plants Exposed to Ozone: An Update. Environ. Sci. Pollut. Res. 2023, 30, 88281–88312. [Google Scholar] [CrossRef]
  16. Fang, Y.; Jiang, J.; Ding, H.; Li, X.; Xie, X. Phospholipase C: Diverse Functions in Plant Biotic Stress Resistance and Fungal Pathogenicity. Mol. Plant Pathol. 2023, 24, 1192–1202. [Google Scholar] [CrossRef]
  17. Ahmed, T.; Noman, M.; Gardea-Torresdey, J.L.; White, J.C.; Li, B. Dynamic Interplay between Nano-Enabled Agrochemicals and the Plant-Associated Microbiome. Trends Plant Sci. 2023, 28, 1310–1325. [Google Scholar] [CrossRef] [PubMed]
  18. Sharma, S.; Kumar, A.; Choudhary, A.; Harish, B.M.; Karmakar, P.; Sharma, P.; Singh, J.; Pandey, V.; Mehta, S. Recent Developments in Smart Nano-Agrochemicals: A Promise for Revolutionizing Present-Day Agriculture. Mater. Today Proc. 2022, 69, 530–534. [Google Scholar] [CrossRef]
  19. Zhang, Y.; Goss, G.G. Nanotechnology in Agriculture: Comparison of the Toxicity between Conventional and Nano-Based Agrochemicals on Non-Target Aquatic Species. J. Hazard. Mater. 2022, 439, 129559. [Google Scholar] [CrossRef]
  20. Giri, V.P.; Shukla, P.; Tripathi, A.; Verma, P.; Kumar, N.; Pandey, S.; Dimkpa, C.O.; Mishra, A. A Review of Sustainable Use of Biogenic Nanoscale Agro-Materials to Enhance Stress Tolerance and Nutritional Value of Plants. Plants 2023, 12, 815. [Google Scholar] [CrossRef]
  21. Mubeen, I.; Fawzi Bani Mfarrej, M.; Razaq, Z.; Iqbal, S.; Naqvi, S.A.H.; Hakim, F.; Mosa, W.F.A.; Moustafa, M.; Fang, Y.; Li, B. Nanopesticides in Comparison with Agrochemicals: Outlook and Future Prospects for Sustainable Agriculture. Plant Physiol. Biochem. 2023, 198, 107670. [Google Scholar] [CrossRef]
  22. Khalid, F.; Asif, K.; Rasheed, Y.; Ashraf, H.; Maqsood, M.F.; Rana, S.; Zulfiqar, U.; Naz, N.; Shahbaz, M.; Sardar, R.; et al. Nano Priming for Boosting Growth and Resilience in Crops under Abiotic Stresses. Biocatal. Agric. Biotechnol. 2023, 53, 102892. [Google Scholar] [CrossRef]
  23. Sári, D.; Ferroudj, A.; Dávid, S.; El-Ramady, H.; Faizy, S.; Ibrahim, S.; Mansour, H.; Brevik, E.; Solberg, S.; Prokisch, J. Drought Stress Under a Nano-Farming Approach: A Review. Egypt. J. Soil Sci. 2024, 64, 135–151. [Google Scholar] [CrossRef]
  24. Mohammadi, S.; Jabbari, F.; Cidonio, G.; Babaeipour, V. Revolutionizing Agriculture: Harnessing Nano-Innovations for Sustainable Farming and Environmental Preservation. Pestic. Biochem. Physiol. 2024, 198, 105722. [Google Scholar] [CrossRef] [PubMed]
  25. El-Saadony, M.T.; Saad, A.M.; Najjar, A.A.; Alzahrani, S.O.; Alkhatib, F.M.; Shafi, M.E.; Selem, E.; Desoky, E.-S.M.; Fouda, S.E.E.; El-Tahan, A.M.; et al. The Use of Biological Selenium Nanoparticles to Suppress Triticum aestivum L. Crown and Root Rot Diseases Induced by Fusarium Species and Improve Yield under Drought and Heat Stress. Saudi J. Biol. Sci. 2021, 28, 4461–4471. [Google Scholar] [CrossRef] [PubMed]
  26. El-Ramady, H.; Abdalla, N.; Sári, D.; Ferroudj, A.; Muthu, A.; Prokisch, J.; Fawzy, Z.F.; Brevik, E.C.; Solberg, S.Ø. Nanofarming: Promising Solutions for the Future of the Global Agricultural Industry. Agronomy 2023, 13, 1600. [Google Scholar] [CrossRef]
  27. Ijaz, M.; Khan, F.; Ahmed, T.; Noman, M.; Zulfiqar, F.; Rizwan, M.; Chen, J.; Siddique, H.M.K.; Li, B. Nanobiotechnology to Advance Stress Resilience in Plants: Current Opportunities and Challenges. Mater. Today Bio 2023, 22, 100759. [Google Scholar] [CrossRef] [PubMed]
  28. Sári, D.; Ferroudj, A.; Muthu, A.; Prokisch, J.; El-Ramady, H.; Elsakhawy, T.; Omara, A.E.-D.; Brevik, E. Nano-Enabled Agriculture Using Nano-Selenium for Crop Productivity: What Should Be Addressed More? Environ. Biodivers. Soil Secur. 2023, 7, 85–99. [Google Scholar] [CrossRef]
  29. Sharma, P.; Lakra, N.; Goyal, A.; Ahlawat, Y.K.; Zaid, A.; Siddique, K.H.M. Drought and Heat Stress Mediated Activation of Lipid Signaling in Plants: A Critical Review. Front. Plant Sci. 2023, 14, 1216835. [Google Scholar] [CrossRef]
  30. Zhao, W.; Wu, Z.; Amde, M.; Zhu, G.; Wei, Y.; Zhou, P.; Zhang, Q.; Song, M.; Tan, Z.; Zhang, P.; et al. Nanoenabled Enhancement of Plant Tolerance to Heat and Drought Stress on Molecular Response. J. Agric. Food Chem. 2023, 71, 20405–20418. [Google Scholar] [CrossRef]
  31. Sato, H.; Mizoi, J.; Shinozaki, K.; Yamaguchi-Shinozaki, K. Complex Plant Responses to Drought and Heat Stress under Climate Change. Plant J. 2024, 117, 1873–1892. [Google Scholar] [CrossRef] [PubMed]
  32. El-Ramady, H.; Prokisch, J.; Mansour, H.; Bayoumi, Y.A.; Shalaby, T.A.; Veres, S.; Brevik, E.C. Review of Crop Response to Soil Salinity Stress: Possible Approaches from Leaching to Nano-Management. Soil Syst. 2024, 8, 11. [Google Scholar] [CrossRef]
  33. Garoosi, M.K.; Sanjarian, F.; Chaichi, M. The Role of γ-Aminobutyric Acid and Salicylic Acid in Heat Stress Tolerance under Salinity Conditions in Origanum vulgare L. PLoS ONE 2023, 18, e0288169. [Google Scholar] [CrossRef] [PubMed]
  34. Nahar, L.; Aycan, M.; Lopes Hornai, E.M.; Baslam, M.; Mitsui, T. Tolerance with High Yield Potential Is Provided by Lower Na+ Ion Accumulation and Higher Photosynthetic Activity in Tolerant YNU31-2-4 Rice Genotype under Salinity and Multiple Heat and Salinity Stress. Plants 2023, 12, 1910. [Google Scholar] [CrossRef] [PubMed]
  35. Sun, C.; Meng, S.; Wang, B.; Zhao, S.; Liu, Y.; Qi, M.; Wang, Z.; Yin, Z.; Li, T. Exogenous Melatonin Enhances Tomato Heat Resistance by Regulating Photosynthetic Electron Flux and Maintaining ROS Homeostasis. Plant Physiol. Biochem. 2023, 196, 197–209. [Google Scholar] [CrossRef]
  36. Kumar, R.; Bahuguna, R.N.; Tiwari, M.; Pal, M.; Chinnusamy, V.; Sreeman, S.; Muthurajan, R.; Krishna Jagadish, S.V. Walking through Crossroads–Rice Responses to Heat and Biotic Stress Interactions. Theor. Appl. Genet. 2022, 135, 4065–4081. [Google Scholar] [CrossRef] [PubMed]
  37. Mondal, S.; Karmakar, S.; Panda, D.; Pramanik, K.; Bose, B.; Singhal, R.K. Crucial Plant Processes under Heat Stress and Tolerance through Heat Shock Proteins. Plant Stress 2023, 10, 100227. [Google Scholar] [CrossRef]
  38. Gao, G.; Yan, L.; Tong, K.; Yu, H.; Lu, M.; Wang, L.; Niu, Y. The Potential and Prospects of Modified Biochar for Comprehensive Management of Salt-Affected Soils and Plants: A Critical Review. Sci. Total Environ. 2024, 912, 169618. [Google Scholar] [CrossRef]
  39. Rao, Y.; Peng, T.; Xue, S. Mechanisms of Plant Saline-Alkaline Tolerance. J. Plant Physiol. 2023, 281, 153916. [Google Scholar] [CrossRef]
  40. Abdelhameed, A.; Abd El-Hady, M.; Mosaad, I. Integrated Organic and Inorganic Amendments for Improving Productivity of Okra (Abelmoschus esculentus L.) in Alkaline Soil. Egypt. J. Soil Sci. 2024, 64, 207–219. [Google Scholar] [CrossRef]
  41. Yemelyanov, V.V.; Puzanskiy, R.K.; Shishova, M.F. Plant Life with and without Oxygen: A Metabolomics Approach. Int. J. Mol. Sci. 2023, 24, 16222. [Google Scholar] [CrossRef]
  42. Feng, X.; Teng, J.; Wang, H. Influence Mechanism of Water Content and Compaction Degree on Shear Strength of Red Clay with High Liquid Limit. Materials 2023, 17, 162. [Google Scholar] [CrossRef] [PubMed]
  43. Brevik, E.; Fenton, T.; Moran, L. Effect of Soil Compaction on Organic Carbon Amounts and Distribution, South-Central Iowa. Environ. Pollut. 2002, 116, S137–S141. [Google Scholar] [CrossRef] [PubMed]
  44. Abdalla, Z.; El-Bassiony, A.E.-M.; El-Ramady, H.; El-Sawy, S.; Shedeed, S. Broccoli Biofortification Using Biological Nano- and Mineral Fertilizers of Selenium: A Comparative Study under Soil Nutrient Deficiency Stress. Egypt. J. Soil Sci. 2022, 63, 57–66. [Google Scholar] [CrossRef]
  45. Mahmoud, S.; Shedeed, S.; El-Ramady, H.; Abdalla, Z.; El-Bassiony, A.E.-M.; El-Sawy, S. Biological Nano-Selenium for Eggplant Biofortification under Soil Nutrient Deficiency. Egypt. J. Soil Sci. 2023, 63, 151–162. [Google Scholar] [CrossRef]
  46. Narayanan, M.; Ma, Y. Mitigation of Heavy Metal Stress in the Soil through Optimized Interaction between Plants and Microbes. J. Environ. Manag. 2023, 345, 118732. [Google Scholar] [CrossRef] [PubMed]
  47. Gayathiri, E.; Prakash, P.; Pandiaraj, S.; Ramasubburayan, R.; Gaur, A.; Sekar, M.; Viswanathan, D.; Govindasamy, R. Investigating the Ecological Implications of Nanomaterials: Unveiling Plants’ Notable Responses to Nano-Pollution. Plant Physiol. Biochem. 2024, 206, 108261. [Google Scholar] [CrossRef]
  48. Dutta, P.; Mahanta, M.; Singh, S.B.; Thakuria, D.; Deb, L.; Kumari, A.; Upamanya, G.K.; Boruah, S.; Dey, U.; Mishra, A.K.; et al. Molecular Interaction between Plants and Trichoderma Species against Soil-Borne Plant Pathogens. Front. Plant Sci. 2023, 14, 1145715. [Google Scholar] [CrossRef] [PubMed]
  49. Rocha, L.F.; Bond, J.P.; Fakhoury, A.M. Wheat Production Alters Soil Microbial Profiles and Enhances Beneficial Microbes in Double-Cropping Soybean. Front. Agron. 2022, 3, 807112. [Google Scholar] [CrossRef]
  50. Jimenez, R.; Ardila, A.V.; Vargas-Burbano, A.C.; Hernandez, A.J.; Leon-Velasquez, E. Biomass Burning-Agriculture Coupling in the Orinoco Savannas—Particulate Matter Emission Scenarios. Front. Environ. Sci. 2022, 10, 689844. [Google Scholar] [CrossRef]
  51. Jia, Y.; Kang, L.; Wu, Y.; Zhou, C.; Li, D.; Li, J.; Pan, C. Review on Pesticide Abiotic Stress over Crop Health and Intervention by Various Biostimulants. J. Agric. Food Chem. 2023, 71, 13595–13611. [Google Scholar] [CrossRef]
  52. Feng, D.; Jia, X.; Yan, Z.; Li, J.; Gao, J.; Xiao, W.; Shen, X.; Sun, X. Underlying Mechanisms of Exogenous Substances Involved in Alleviating Plant Heat Stress. Plant Stress 2023, 10, 100288. [Google Scholar] [CrossRef]
  53. Zantis, L.J.; Borchi, C.; Vijver, M.G.; Peijnenburg, W.; Di Lonardo, S.; Bosker, T. Nano- and Microplastics Commonly Cause Adverse Impacts on Plants at Environmentally Relevant Levels: A Systematic Review. Sci. Total Environ. 2023, 867, 161211. [Google Scholar] [CrossRef] [PubMed]
  54. Khan, S.; Galstyan, H.; Abbas, M.; Wenjing, X. Advanced Biotechnology Strategies for Detoxification of Persistent Organic Pollutants and Toxic Elements in Soil. Chemosphere 2023, 345, 140519. [Google Scholar] [CrossRef] [PubMed]
  55. Macchi, C.; Sirtori, C.R.; Corsini, A.; Mannuccio Mannucci, P.; Ruscica, M. Pollution from Fine Particulate Matter and Atherosclerosis: A Narrative Review. Environ. Int. 2023, 175, 107923. [Google Scholar] [CrossRef] [PubMed]
  56. Xia, X.; Hao, L.; Sun, Y.; Lv, Y.; Wang, Y.; Wu, H.; Jiang, Z.; Li, X.; Yan, Y.; Chen, X.; et al. Unravelling Chilling-Stress Resistance Mechanisms in Endangered Mangrove Plant Lumnitzera Littorea (Jack) Voigt. Mar. Environ. Res. 2023, 192, 106210. [Google Scholar] [CrossRef] [PubMed]
  57. Gusain, S.; Joshi, S.; Joshi, R. Sensing, Signalling, and Regulatory Mechanism of Cold-Stress Tolerance in Plants. Plant Physiol. Biochem. 2023, 197, 107646. [Google Scholar] [CrossRef]
  58. Kong, Y.; Deering, A.J.; Nemali, K. Minimizing Escherichia coli O157:H7 Contamination in Indoor Farming: Effects of Cultivar Type and ultra-violet Light Quality. J. Sci. Food Agric. 2024, 104, 4218–4225. [Google Scholar] [CrossRef] [PubMed]
  59. Müller, K.; Keller, M.; Stoll, M.; Friedel, M. Wind Speed, Sun Exposure and Water Status Alter Sunburn Susceptibility of Grape Berries. Front. Plant Sci. 2023, 14, 1145274. [Google Scholar] [CrossRef]
  60. Lv, P.; Sun, S.; Li, Y.; Zhao, S.; Zhang, J.; Hu, Y.; Yue, P.; Zuo, X. Plant Composition Change Mediates Climate Drought, Nitrogen Addition, and Grazing Effects on Soil Net Nitrogen Mineralization in a Semi-Arid Grassland in North China. Sci. Total Environ. 2024, 908, 168282. [Google Scholar] [CrossRef]
  61. Marroquin, A.; Holmes, K.; Salazar, D. Soil Salinization and Chemically Mediated Plant–Insect Interactions in a Changing Climate. Curr. Opin. Insect Sci. 2023, 60, 101130. [Google Scholar] [CrossRef]
  62. Kashyap, S.; Sharma, I.; Dowarah, B.; Barman, R.; Gill, S.S.; Agarwala, N. Plant and Soil-Associated Microbiome Dynamics Determine the Fate of Bacterial Wilt Pathogen Ralstonia Solanacearum. Planta 2023, 258, 57. [Google Scholar] [CrossRef]
  63. Viswanath, K.K.; Kuo, S.-Y.; Tu, C.-W.; Hsu, Y.-H.; Huang, Y.-W.; Hu, C.-C. The Role of Plant Transcription Factors in the Fight against Plant Viruses. Int. J. Mol. Sci. 2023, 24, 8433. [Google Scholar] [CrossRef]
  64. Shalaby, T.A.; Abd-Alkarim, E.; El-Aidy, F.; Hamed, E.-S.; Sharaf-Eldin, M.; Taha, N.; El-Ramady, H.; Bayoumi, Y.; Dos Reis, A.R. Nano-Selenium, Silicon and H2O2 Boost Growth and Productivity of Cucumber under Combined Salinity and Heat Stress. Ecotoxicol. Environ. Saf. 2021, 212, 111962. [Google Scholar] [CrossRef]
  65. Mattos, C.R.C.; Hirota, M.; Oliveira, R.S.; Flores, B.M.; Miguez-Macho, G.; Pokhrel, Y.; Fan, Y. Double Stress of Waterlogging and Drought Drives Forest–Savanna Coexistence. Proc. Natl. Acad. Sci. USA 2023, 120, e2301255120. [Google Scholar] [CrossRef]
  66. Benali, A.; El Haddad, N.; Patil, S.B.; Goyal, A.; Hejjaoui, K.; El Baouchi, A.; Gaboun, F.; Taghouti, M.; Ouhssine, M.; Kumar, S. Impact of Terminal Heat and Combined Heat-Drought Stress on Plant Growth, Yield, Grain Size, and Nutritional Quality in Chickpea (Cicer arietinum L.). Plants 2023, 12, 3726. [Google Scholar] [CrossRef]
  67. Liu, Z.; Shi, L.; Yang, S.; Qiu, S.; Ma, X.; Cai, J.; Guan, D.; Wang, Z.; He, S. A Conserved double-W Box in the Promoter of CaWRKY40 Mediates Autoregulation during Response to Pathogen Attack and Heat Stress in Pepper. Mol. Plant Pathol. 2021, 22, 3–18. [Google Scholar] [CrossRef]
  68. Helber, S.B.; Procaccini, G.; Belshe, E.F.; Santillan-Sarmiento, A.; Cardini, U.; Bröhl, S.; Schmid, M.; Reuter, H.; Teichberg, M. Unusually Warm Summer Temperatures Exacerbate Population and Plant Level Response of Posidonia Oceanica to Anthropogenic Nutrient Stress. Front. Plant Sci. 2021, 12, 662682. [Google Scholar] [CrossRef]
  69. Mohorović, P.; Geldhof, B.; Holsteens, K.; Rinia, M.; Ceusters, J.; Van De Poel, B. Effect of Ethylene Pretreatment on Tomato Plant Responses to Salt, Drought, and Waterlogging Stress. Plant Direct 2023, 7, e548. [Google Scholar] [CrossRef]
  70. Broberg, M.C.; Hayes, F.; Harmens, H.; Uddling, J.; Mills, G.; Pleijel, H. Effects of Ozone, Drought and Heat Stress on Wheat Yield and Grain Quality. Agric. Ecosyst. Environ. 2023, 352, 108505. [Google Scholar] [CrossRef]
  71. Hassan, M.U.; Chattha, M.U.; Khan, I.; Chattha, M.B.; Barbanti, L.; Aamer, M.; Iqbal, M.M.; Nawaz, M.; Mahmood, A.; Ali, A.; et al. Heat Stress in Cultivated Plants: Nature, Impact, Mechanisms, and Mitigation Strategies—A Review. Plant Biosyst.-Int. J. Deal. Asp. Plant Biol. 2021, 155, 211–234. [Google Scholar] [CrossRef]
  72. Enayati, M.; Bozorg-Haddad, O.; Fallah-Mehdipour, E.; Zolghadr-Asli, B.; Chu, X. A Robust Multiple-Objective Decision-Making Paradigm Based on the Water–Energy–Food Security Nexus under Changing Climate Uncertainties. Sci. Rep. 2021, 11, 20927. [Google Scholar] [CrossRef] [PubMed]
  73. Shalaby, T.; Bayoumi, Y.; Eid, Y.; Elbasiouny, H.; Elbehiry, F.; Prokisch, J.; El-Ramady, H.; Ling, W. Can Nanofertilizers Mitigate Multiple Environmental Stresses for Higher Crop Productivity? Sustainability 2022, 14, 3480. [Google Scholar] [CrossRef]
  74. Dos Santos, T.B.; Ribas, A.F.; De Souza, S.G.H.; Budzinski, I.G.F.; Domingues, D.S. Physiological Responses to Drought, Salinity, and Heat Stress in Plants: A Review. Stresses 2022, 2, 113–135. [Google Scholar] [CrossRef]
  75. Ahmad, M.; Imtiaz, M.; Shoib Nawaz, M.; Mubeen, F.; Imran, A. What Did We Learn From Current Progress in Heat Stress Tolerance in Plants? Can Microbes Be a Solution? Front. Plant Sci. 2022, 13, 794782. [Google Scholar] [CrossRef]
  76. Mishra, S.; Spaccarotella, K.; Gido, J.; Samanta, I.; Chowdhary, G. Effects of Heat Stress on Plant-Nutrient Relations: An Update on Nutrient Uptake, Transport, and Assimilation. Int. J. Mol. Sci. 2023, 24, 15670. [Google Scholar] [CrossRef] [PubMed]
  77. Zhao, J.; Lu, Z.; Wang, L.; Jin, B. Plant Responses to Heat Stress: Physiology, Transcription, Noncoding RNAs, and Epigenetics. Int. J. Mol. Sci. 2020, 22, 117. [Google Scholar] [CrossRef] [PubMed]
  78. Georgieva, M.; Vassileva, V. Stress Management in Plants: Examining Provisional and Unique Dose-Dependent Responses. Int. J. Mol. Sci. 2023, 24, 5105. [Google Scholar] [CrossRef]
  79. Zandalinas, S.I.; Sengupta, S.; Fritschi, F.B.; Azad, R.K.; Nechushtai, R.; Mittler, R. The Impact of Multifactorial Stress Combination on Plant Growth and Survival. New Phytol. 2021, 230, 1034–1048. [Google Scholar] [CrossRef]
  80. Duc, N.H.; Szentpéteri, V.; Mayer, Z.; Posta, K. Distinct Impact of Arbuscular Mycorrhizal Isolates on Tomato Plant Tolerance to Drought Combined with Chronic and Acute Heat Stress. Plant Physiol. Biochem. 2023, 201, 107892. [Google Scholar] [CrossRef]
  81. Lama, S.; Leiva, F.; Vallenback, P.; Chawade, A.; Kuktaite, R. Impacts of Heat, Drought, and Combined Heat–Drought Stress on Yield, Phenotypic Traits, and Gluten Protein Traits: Capturing Stability of Spring Wheat in Excessive Environments. Front. Plant Sci. 2023, 14, 1179701. [Google Scholar] [CrossRef]
  82. Riedesel, L.; Möller, M.; Horney, P.; Golla, B.; Piepho, H.-P.; Kautz, T.; Feike, T. Timing and Intensity of Heat and Drought Stress Determine Wheat Yield Losses in Germany. PLoS ONE 2023, 18, e0288202. [Google Scholar] [CrossRef] [PubMed]
  83. Yuan, A.; Kumar, S.D.; Wang, H.; Wang, S.; Impa, S.; Wang, H.; Guo, J.; Wang, Y.; Yang, Q.; Liu, X.J.A.; et al. Dynamic Interplay among Soil Nutrients, Rhizosphere Metabolites, and Microbes Shape Drought and Heat Stress Responses in Summer Maize. Soil Biol. Biochem. 2024, 191, 109357. [Google Scholar] [CrossRef]
  84. Da Costa, M.V.J.; Ramegowda, V.; Ramakrishnan, P.; Nataraja, K.N.; Sheshshayee, M.S. Comparative Metabolite Profiling of Rice Contrasts Reveal Combined Drought and Heat Stress Signatures in Flag Leaf and Spikelets. Plant Sci. 2022, 320, 111262. [Google Scholar] [CrossRef]
  85. Rahman, M.M.; Mostofa, M.G.; Keya, S.S.; Ghosh, P.K.; Abdelrahman, M.; Anik, T.R.; Gupta, A.; Tran, L.-S.P. Jasmonic Acid Priming Augments Antioxidant Defense and Photosynthesis in Soybean to Alleviate Combined Heat and Drought Stress Effects. Plant Physiol. Biochem. 2024, 206, 108193. [Google Scholar] [CrossRef] [PubMed]
  86. Juneja, S.; Saini, R.; Adhikary, A.; Yadav, R.; Khan, S.A.; Nayyar, H.; Kumar, S. Drought Priming Evokes Essential Regulation of Hsp Gene Families, Hsfs and Their Related miRNAs and Induces Heat Stress Tolerance in Chickpea. Plant Stress 2023, 10, 100189. [Google Scholar] [CrossRef]
  87. Charfeddine, M.; Chiab, N.; Charfeddine, S.; Ferjani, A.; Gargouri-Bouzid, R. Heat, Drought, and Combined Stress Effect on Transgenic Potato Plants Overexpressing the StERF94 Transcription Factor. J. Plant Res. 2023, 136, 549–562. [Google Scholar] [CrossRef] [PubMed]
  88. Shashikumara, P.; Gajghate, R.; Bhatt Devate, N.; Harikrishna; Mamrutha, H.M.; Gopalareddy, K.; Singh, G.P. Heat Stress in Wheat: Adaptation Strategies. In Thermotolerance in Crop Plants; Kumar, R.R., Praveen, S., Rai, G.K., Eds.; Springer Nature: Singapore, 2022; pp. 1–21. ISBN 978-981-19379-9-6. [Google Scholar]
  89. Ru, C.; Hu, X.; Chen, D.; Wang, W.; Zhen, J. Photosynthetic, Antioxidant Activities, and Osmoregulatory Responses in Winter Wheat Differ during the Stress and Recovery Periods under Heat, Drought, and Combined Stress. Plant Sci. 2023, 327, 111557. [Google Scholar] [CrossRef]
  90. Smith, J.; Wijewardene, I.; Cai, Y.; Esmaeili, N.; Shen, G.; Hequet, E.; Ritchie, G.; Payton, P.; Zhang, H. Co-Overexpression of RCA and AVP1 in Cotton Substantially Improves Fiber Yield for Cotton under Drought, Moderate Heat, and Salt Stress Conditions. Curr. Res. Biotechnol. 2023, 5, 100123. [Google Scholar] [CrossRef]
  91. Labuschagne, M.; Guzmán, C.; Crossa, J.; Van Biljon, A. Determining Factors of Durum Wheat Bread Loaf Volume and Alveograph Characteristics under Optimal, Drought and Heat Stress Conditions. J. Cereal Sci. 2023, 114, 103791. [Google Scholar] [CrossRef]
  92. Kumar, R.; Adhikary, A.; Saini, R.; Khan, S.A.; Yadav, M.; Kumar, S. Drought Priming Induced Thermotolerance in Wheat (Triticum aestivum L.) during Reproductive Stage; a Multifaceted Tolerance Approach against Terminal Heat Stress. Plant Physiol. Biochem. 2023, 201, 107840. [Google Scholar] [CrossRef]
  93. Pernicová, N.; Hlaváčová, M.; Findurová, H.; Čáslavský, J.; Urban, O.; Klem, K.; Trnka, M. Grain Carbon Isotopes Indicate the Ability of Wheat Plants to Maintain Enhanced Intrinsic Water-Use Efficiency Even after Short-Term Exposure to High Temperatures and Drought. Plant Physiol. Biochem. 2023, 205, 108155. [Google Scholar] [CrossRef] [PubMed]
  94. Aloui, K.; Choukri, H.; El Haddad, N.; Gupta, P.; El Bouhmadi, K.; Emmrich, P.M.F.; Singh, A.; Edwards, A.; Maalouf, F.; Bouhlal, O.; et al. Impact of Heat and Drought Stress on Grasspea and Its Wild Relatives. Plants 2023, 12, 3501. [Google Scholar] [CrossRef]
  95. Kashyap, A.; Kumari, S.; Garg, P.; Kushwaha, R.; Tripathi, S.; Sharma, J.; Gupta, N.C.; Kumar, R.R.; Yadav, R.; Vishwakarma, H.; et al. Indexing Resilience to Heat and Drought Stress in the Wild Relatives of Rapeseed-Mustard. Life 2023, 13, 738. [Google Scholar] [CrossRef] [PubMed]
  96. Puppala, N.; Nayak, S.N.; Sanz-Saez, A.; Chen, C.; Devi, M.J.; Nivedita, N.; Bao, Y.; He, G.; Traore, S.M.; Wright, D.A.; et al. Sustaining Yield and Nutritional Quality of Peanuts in Harsh Environments: Physiological and Molecular Basis of Drought and Heat Stress Tolerance. Front. Genet. 2023, 14, 1121462. [Google Scholar] [CrossRef] [PubMed]
  97. Hualpa-Ramirez, E.; Carrasco-Lozano, E.C.; Madrid-Espinoza, J.; Tejos, R.; Ruiz-Lara, S.; Stange, C.; Norambuena, L. Stress Salinity in Plants: New Strategies to Cope with in the Foreseeable Scenario. Plant Physiol. Biochem. 2024, 208, 108507. [Google Scholar] [CrossRef] [PubMed]
  98. Zhang, X.; Ma, M.; Wu, C.; Huang, S.; Danish, S. Mitigation of Heat Stress in Wheat (Triticum aestivum L.) via Regulation of Physiological Attributes Using Sodium Nitroprusside and Gibberellic Acid. BMC Plant Biol. 2023, 23, 302. [Google Scholar] [CrossRef] [PubMed]
  99. Bayoumi, Y.; Abd-Alkarim, E.; El-Ramady, H.; El-Aidy, F.; Hamed, E.-S.; Taha, N.; Prohens, J.; Rakha, M. Grafting Improves Fruit Yield of Cucumber Plants Grown under Combined Heat and Soil Salinity Stresses. Horticulturae 2021, 7, 61. [Google Scholar] [CrossRef]
  100. Abbas, G.; Areej, F.; Asad, S.A.; Saqib, M.; Anwar-ul-Haq, M.; Afzal, S.; Murtaza, B.; Amjad, M.; Naeem, M.A.; Akram, M.; et al. Differential Effect of Heat Stress on Drought and Salt Tolerance Potential of Quinoa Genotypes: A Physiological and Biochemical Investigation. Plants 2023, 12, 774. [Google Scholar] [CrossRef]
  101. David-Rogeat, N.; Broadley, M.R.; Stavridou, E. Heat and Salinity Stress on the African Eggplant F1 Djamba, a Kumba Cultivar. Front. Plant Sci. 2024, 15, 1323665. [Google Scholar] [CrossRef]
  102. Omar, S.; Salim, H.; Eldenary, M.; Nosov, A.V.; Allakhverdiev, S.I.; Alfiky, A. Ameliorating Effect of Nanoparticles and Seeds’ Heat Pre-Treatment on Soybean Plants Exposed to Sea Water Salinity. Heliyon 2023, 9, e21446. [Google Scholar] [CrossRef]
  103. Lee, J.H.J.; Kasote, D.M. Nano-Priming for Inducing Salinity Tolerance, Disease Resistance, Yield Attributes, and Alleviating Heavy Metal Toxicity in Plants. Plants 2024, 13, 446. [Google Scholar] [CrossRef]
  104. Zhao, L.; Zhou, X.; Kang, Z.; Peralta-Videa, J.R.; Zhu, Y.-G. Nano-Enabled Seed Treatment: A New and Sustainable Approach to Engineering Climate-Resilient Crops. Sci. Total Environ. 2024, 910, 168640. [Google Scholar] [CrossRef]
  105. Chaudhary, M.T.; Majeed, S.; Rana, I.A.; Ali, Z.; Jia, Y.; Du, X.; Hinze, L.; Azhar, M.T. Impact of Salinity Stress on Cotton and Opportunities for Improvement through Conventional and Biotechnological Approaches. BMC Plant Biol. 2024, 24, 20. [Google Scholar] [CrossRef] [PubMed]
  106. Aouz, A.; Khan, I.; Chattha, M.B.; Ahmad, S.; Ali, M.; Ali, I.; Ali, A.; Alqahtani, F.M.; Hashem, M.; Albishi, T.S.; et al. Silicon Induces Heat and Salinity Tolerance in Wheat by Increasing Antioxidant Activities, Photosynthetic Activity, Nutrient Homeostasis, and Osmo-Protectant Synthesis. Plants 2023, 12, 2606. [Google Scholar] [CrossRef] [PubMed]
  107. Chen, S.; Zhao, C.-B.; Ren, R.-M.; Jiang, J.-H. Salicylic Acid Had the Potential to Enhance Tolerance in Horticultural Crops against Abiotic Stress. Front. Plant Sci. 2023, 14, 1141918. [Google Scholar] [CrossRef]
  108. Rodrigues, F.; Sousa, B.; Soares, C.; Moreira, D.; Pereira, C.; Moutinho-Pereira, J.; Cunha, A.; Fidalgo, F. Are Tomato Plants Co-Exposed to Heat and Salinity Able to Ensure a Proper Carbon Metabolism?—An Insight into the Photosynthetic Hub. Plant Physiol. Biochem. 2024, 206, 108270. [Google Scholar] [CrossRef]
  109. Gholamnia, A.; Mosleh Arani, A.; Sodaeizadeh, H.; Tarkesh Esfahani, S.; Ghasemi, S. Expression Profiling of Rosmarinic Acid Biosynthetic Genes and Some Physiological Responses from Mentha Piperita L. under Salinity and Heat Stress. Physiol. Mol. Biol. Plants 2022, 28, 545–557. [Google Scholar] [CrossRef] [PubMed]
  110. Attar, A.Z.; Ahmed, T.; Kato, A.; Saadaoui, I.; Shabala, S. Understanding Impact of Heat, Drought, and Salinity Stresses on Growth and Physiological Attributes of Chenopodium Album under Field Conditions. Plant Growth Regul. 2023, 100, 107–118. [Google Scholar] [CrossRef]
  111. Yadav, A.; Yadav, K.; Abd-Elsalam, K.A. Exploring the Potential of Nanofertilizers for a Sustainable Agriculture. Plant Nano Biol. 2023, 5, 100044. [Google Scholar] [CrossRef]
  112. Nahar, L.; Aycan, M.; Hanamata, S.; Baslam, M.; Mitsui, T. Impact of Single and Combined Salinity and High-Temperature Stresses on Agro-Physiological, Biochemical, and Transcriptional Responses in Rice and Stress-Release. Plants 2022, 11, 501. [Google Scholar] [CrossRef] [PubMed]
  113. Desaint, H.; Aoun, N.; Deslandes, L.; Vailleau, F.; Roux, F.; Berthomé, R. Fight Hard or Die Trying: When Plants Face Pathogens under Heat Stress. New Phytol. 2021, 229, 712–734. [Google Scholar] [CrossRef] [PubMed]
  114. Priya, P.; Patil, M.; Pandey, P.; Singh, A.; Babu, V.S.; Senthil-Kumar, M. Stress Combinations and Their Interactions in Plants Database: A One-stop Resource on Combined Stress Responses in Plants. Plant J. 2023, 116, 1097–1117. [Google Scholar] [CrossRef]
  115. Carreiras, J.; Cruz-Silva, A.; Fonseca, B.; Carvalho, R.C.; Cunha, J.P.; Proença Pereira, J.; Paiva-Silva, C.; Santos, S.A.; Janeiro Sequeira, R.; Mateos-Naranjo, E.; et al. Improving Grapevine Heat Stress Resilience with Marine Plant Growth-Promoting Rhizobacteria Consortia. Microorganisms 2023, 11, 856. [Google Scholar] [CrossRef] [PubMed]
  116. Gardner, H.; Onofre, K.F.A.; De Wolf, E.D. Characterizing the Response of Puccinia Striiformis f. Sp. Tritici to Periods of Heat Stress That Are Common in Kansas and the Great Plains Region of North America. Phytopathology 2023, 113, 1457–1464. [Google Scholar] [CrossRef] [PubMed]
  117. Chauhan, Y.S.; Anwar, M.R.; Richards, M.F.; Lake, L.; Sadras, V.O.; Luckett, D.J.; Raman, R.; Krosch, S.; Graham, N. Effect of Soil Water on Flowering and Pod-Set in Chickpea: Implications for Modelling and Managing Frost and Heat Stress. Agron. Sustain. Dev. 2023, 43, 49. [Google Scholar] [CrossRef]
  118. Devi, J.; Sagar, V.; Mishra, G.P.; Jha, P.K.; Gupta, N.; Dubey, R.K.; Singh, P.M.; Behera, T.K.; Prasad, P.V.V. Heat Stress Tolerance in Peas (Pisum sativum L.): Current Status and Way Forward. Front. Plant Sci. 2023, 13, 1108276. [Google Scholar] [CrossRef] [PubMed]
  119. Rys, M.; Saja-Garbarz, D.; Fodor, J.; Oliwa, J.; Gullner, G.; Juhász, C.; Kornaś, A.; Skoczowski, A.; Gruszka, D.; Janeczko, A.; et al. Heat Pre-Treatment Modified Host and Non-Host Interactions of Powdery Mildew with Barley Brassinosteroid Mutants and Wild Types. Life 2024, 14, 160. [Google Scholar] [CrossRef]
  120. Omar, A.A.; Heikal, Y.M.; Zayed, E.M.; Shamseldin, S.A.M.; Salama, Y.E.; Amer, K.E.; Basuoni, M.M.; Abd Ellatif, S.; Mohamed, A.H. Conferring of Drought and Heat Stress Tolerance in Wheat (Triticum aestivum L.) Genotypes and Their Response to Selenium Nanoparticles Application. Nanomaterials 2023, 13, 998. [Google Scholar] [CrossRef]
  121. Tsai, S.-H.; Hsiao, Y.-C.; Chang, P.E.; Kuo, C.-E.; Lai, M.-C.; Chuang, H. Exploring the Biologically Active Metabolites Produced by Bacillus Cereus for Plant Growth Promotion, Heat Stress Tolerance, and Resistance to Bacterial Soft Rot in Arabidopsis. Metabolites 2023, 13, 676. [Google Scholar] [CrossRef]
  122. Zhang, M.; Trushina, N.K.; Lang, T.; Hahn, M.; Pasmanik-Chor, M.; Sharon, A. Serine Peptidases and Increased Amounts of Soluble Proteins Contribute to Heat Priming of the Plant Pathogenic Fungus Botrytis cinerea. Mbio 2023, 14, e01077-23. [Google Scholar] [CrossRef] [PubMed]
  123. Künstler, A.; Füzék, K.; Schwarczinger, I.; Nagy, J.K.; Bakonyi, J.; Fodor, J.; Hafez, Y.M.; Király, L. Heat Shock-induced Enhanced Susceptibility of Barley to Bipolaris Sorokiniana Is Associated with Elevated ROS Production and Plant Defence-related Gene Expression. Plant Biol. 2023, 25, 803–812. [Google Scholar] [CrossRef] [PubMed]
  124. Cherlinka, V. Heat Stress In Plants: Symptoms, Prevention, and Recovery. Available online: https://eos.com/blog/heat-stress-in-plants/ (accessed on 2 March 2024).
  125. Fortunato, S.; Lasorella, C.; Dipierro, N.; Vita, F.; De Pinto, M.C. Redox Signaling in Plant Heat Stress Response. Antioxidants 2023, 12, 605. [Google Scholar] [CrossRef] [PubMed]
  126. Kumar, R.R.; Jin, B.; Teng, N. Heat Stress: Response, Mitigation, and Tolerance in Plants. Front. Plant Sci. 2023, 14, 1266765. [Google Scholar] [CrossRef] [PubMed]
  127. Resentini, F.; Orozco-Arroyo, G.; Cucinotta, M.; Mendes, M.A. The Impact of Heat Stress in Plant Reproduction. Front. Plant Sci. 2023, 14, 1271644. [Google Scholar] [CrossRef] [PubMed]
  128. Djalovic, I.; Kundu, S.; Bahuguna, R.N.; Pareek, A.; Raza, A.; Singla-Pareek, S.L.; Prasad, P.V.V.; Varshney, R.K. Maize and Heat Stress: Physiological, Genetic, and Molecular Insights. Plant Genome 2023, 17, e20378. [Google Scholar] [CrossRef]
  129. Ma, N.; Lin, H.; Ning, L.; Ji, X.; Wang, F.; Shi, C.; Xu, P.; You, C. Temperature and pH-Dependent Nanogel for Smart Pesticide Delivery with Enhanced Foliar Dispersion and Washout Resistance Can Effectively Control Multiple Plant Diseases. J. Clean. Prod. 2023, 429, 139536. [Google Scholar] [CrossRef]
  130. Ali, S.; Ahmad, N.; Dar, M.A.; Manan, S.; Rani, A.; Alghanem, S.M.S.; Khan, K.A.; Sethupathy, S.; Elboughdiri, N.; Mostafa, Y.S.; et al. Nano-Agrochemicals as Substitutes for Pesticides: Prospects and Risks. Plants 2023, 13, 109. [Google Scholar] [CrossRef]
  131. Sharma, R.; Kumar, V. Nano Enabled Agriculture for Sustainable Soil. Waste Manag. Bull. 2024, 2, 152–161. [Google Scholar] [CrossRef]
  132. Sharma, B.; Tiwari, S.; Kumawat, K.C.; Cardinale, M. Nano-Biofertilizers as Bio-Emerging Strategies for Sustainable Agriculture Development: Potentiality and Their Limitations. Sci. Total Environ. 2023, 860, 160476. [Google Scholar] [CrossRef]
  133. Omran, B.A.; Baek, K.-H. Control of Phytopathogens Using Sustainable Biogenic Nanomaterials: Recent Perspectives, Ecological Safety, and Challenging Gaps. J. Clean. Prod. 2022, 372, 133729. [Google Scholar] [CrossRef]
  134. Chormey, D.S.; Zaman, B.T.; Borahan Kustanto, T.; Erarpat Bodur, S.; Bodur, S.; Tekin, Z.; Nejati, O.; Bakırdere, S. Biogenic Synthesis of Novel Nanomaterials and Their Applications. Nanoscale 2023, 15, 19423–19447. [Google Scholar] [CrossRef] [PubMed]
  135. Bhagat, D.S.; Gurnule, W.B.; Bumbrah, G.S.; Koinkar, P.; Chawla, P.A. Recent Advances in Biomedical Applications of Biogenic Nanomaterials. Curr. Pharm. Biotechnol. 2023, 24, 86–100. [Google Scholar] [CrossRef]
  136. Rathee, S.; Ojha, A.; Upadhyay, A.; Xiao, J.; Bajpai, V.K.; Ali, S.; Shukla, S. Biogenic Engineered Nanomaterials for Enhancing Bioavailability via Developing Nano-Iron-Fortified Smart Foods: Advances, Insight, and Prospects of Nanobionics in Fortification of Food. Food Funct. 2023, 14, 9083–9099. [Google Scholar] [CrossRef] [PubMed]
  137. Abasi, F.; Raja, N.I.; Mashwani, Z.U.R.; Amjad, M.S.; Ehsan, M.; Mustafa, N.; Haroon, M.; Proćków, J. Biogenic Silver Nanoparticles as a Stress Alleviator in Plants: A Mechanistic Overview. Molecules 2022, 27, 3378. [Google Scholar] [CrossRef] [PubMed]
  138. Kah, G.; Chandran, R.; Abrahamse, H. Biogenic Silver Nanoparticles for Targeted Cancer Therapy and Enhancing Photodynamic Therapy. Cells 2023, 12, 2012. [Google Scholar] [CrossRef] [PubMed]
  139. Asmat-Campos, D.; Lindsay Rojas, M.; Carreño-Ortega, A. Toward Sustainable Nanomaterials: An Innovative Ecological Approach for Biogenic Synthesis of TiO2 Nanoparticles with Potential Photocatalytic Activity. Clean. Eng. Technol. 2023, 17, 100702. [Google Scholar] [CrossRef]
  140. Rani, S.; Kumar, P.; Dahiya, P.; Dang, A.S.; Suneja, P. Biogenic Synthesis of Zinc Nanoparticles, Their Applications, and Toxicity Prospects. Front. Microbiol. 2022, 13, 824427. [Google Scholar] [CrossRef] [PubMed]
  141. Kiani, B.H.; Ajmal, Q.; Akhtar, N.; Haq, I.; Abdel-Maksoud, M.A.; Malik, A.; Aufy, M.; Ullah, N. Biogenic Synthesis of Zinc Oxide Nanoparticles Using Citrullus Colocynthis for Potential Biomedical Applications. Plants 2023, 12, 362. [Google Scholar] [CrossRef]
  142. Manzoor, M.A.; Shah, I.H.; Ali Sabir, I.; Ahmad, A.; Albasher, G.; Dar, A.A.; Altaf, M.A.; Shakoor, A. Environmental Sustainable: Biogenic Copper Oxide Nanoparticles as Nano-Pesticides for Investigating Bioactivities against Phytopathogens. Environ. Res. 2023, 231, 115941. [Google Scholar] [CrossRef]
  143. Tang, Y.; Zhao, W.; Zhu, G.; Tan, Z.; Huang, L.; Zhang, P.; Gao, L.; Rui, Y. Nano-Pesticides and Fertilizers: Solutions for Global Food Security. Nanomaterials 2023, 14, 90. [Google Scholar] [CrossRef] [PubMed]
  144. Ghorbani, A.; Emamverdian, A.; Pehlivan, N.; Zargar, M.; Razavi, S.M.; Chen, M. Nano-Enabled Agrochemicals: Mitigating Heavy Metal Toxicity and Enhancing Crop Adaptability for Sustainable Crop Production. J. Nanobiotech. 2024, 22, 91. [Google Scholar] [CrossRef] [PubMed]
  145. Bhaskar, M.; Kumar, A.; Rani, R. Application of Nano Formulations in Agriculture. Biocatal. Agric. Biotechnol. 2023, 54, 102934. [Google Scholar] [CrossRef]
  146. Kareem, H.A.; Saleem, M.F.; Saleem, S.; Rather, S.A.; Wani, S.H.; Siddiqui, M.H.; Alamri, S.; Kumar, R.; Gaikwad, N.B.; Guo, Z.; et al. Zinc Oxide Nanoparticles Interplay With Physiological and Biochemical Attributes in Terminal Heat Stress Alleviation in Mungbean (Vigna radiata L.). Front. Plant Sci. 2022, 13, 842349. [Google Scholar] [CrossRef] [PubMed]
  147. Zahra, N.; Hafeez, M.B.; Ghaffar, A.; Kausar, A.; Zeidi, M.A.; Siddique, K.H.M.; Farooq, M. Plant Photosynthesis under Heat Stress: Effects and Management. Environ. Exp. Bot. 2023, 206, 105178. [Google Scholar] [CrossRef]
  148. Tian, L.; Yu, S.; Zhang, L.; Yang, J.; Feng, B.; Song, Y. Effects of Mulching Types on the Yield and Water Utilization by Broomcorn Millet (Panicum miliaceum): Results of a Study in the Loess Plateau, China. J. Environ. Manag. 2023, 345, 118856. [Google Scholar] [CrossRef] [PubMed]
  149. Wassie, M.; Zhang, W.; Zhang, Q.; Ji, K.; Cao, L.; Chen, L. Exogenous Salicylic Acid Ameliorates Heat Stress-Induced Damages and Improves Growth and Photosynthetic Efficiency in Alfalfa (Medicago sativa L.). Ecotoxicol. Environ. Saf. 2020, 191, 110206. [Google Scholar] [CrossRef]
  150. Luo, Y.; Wang, Y.; Xie, Y.; Gao, Y.; Li, W.; Lang, S. Transcriptomic and Metabolomic Analyses of the Effects of Exogenous Trehalose on Heat Tolerance in Wheat. Int. J. Mol. Sci. 2022, 23, 5194. [Google Scholar] [CrossRef]
  151. Alharbi, K.; Khan, A.A.; Sakit Alhaithloul, H.A.; Al-Harbi, N.A.; Al-Qahtani, S.M.; Aloufi, S.S.; Abdulmajeed, A.M.; Muneer, M.A.; Alghanem, S.M.S.; Zia-ur-Rehman, M.; et al. Synergistic Effect of β-Sitosterol and Biochar Application for Improving Plant Growth of Thymus Vulgaris under Heat Stress. Chemosphere 2023, 340, 139832. [Google Scholar] [CrossRef]
  152. Kareem, H.A.; Hassan, M.U.; Zain, M.; Irshad, A.; Shakoor, N.; Saleem, S.; Niu, J.; Skalicky, M.; Chen, Z.; Guo, Z.; et al. Nanosized Zinc Oxide (n-ZnO) Particles Pretreatment to Alfalfa Seedlings Alleviate Heat-Induced Morpho-Physiological and Ultrastructural Damages. Environ. Pollut. 2022, 303, 119069. [Google Scholar] [CrossRef]
  153. Al Masruri, M.H.K.; Ullah, A.; Farooq, M. Application of Nano Chitosan-Glycinebetaine for Improving Bread Wheat Performance under Combined Drought and Heat Stresses. J. Soil Sci. Plant Nutr. 2023, 23, 3482–3499. [Google Scholar] [CrossRef]
  154. Haydar, M.S.; Ghosh, D.; Roy, S. Slow and Controlled Release Nanofertilizers as an Efficient Tool for Sustainable Agriculture: Recent Understanding and Concerns. Plant Nano Biol. 2024, 7, 100058. [Google Scholar] [CrossRef]
  155. Mahapatra, D.M.; Satapathy, K.C.; Panda, B. Biofertilizers and Nanofertilizers for Sustainable Agriculture: Phycoprospects and Challenges. Sci. Total Environ. 2022, 803, 149990. [Google Scholar] [CrossRef] [PubMed]
  156. Upadhyay, P.K.; Singh, V.K.; Rajanna, G.A.; Dwivedi, B.S.; Dey, A.; Singh, R.K.; Rathore, S.S.; Shekhawat, K.; Babu, S.; Singh, T.; et al. Unveiling the Combined Effect of Nano Fertilizers and Conventional Fertilizers on Crop Productivity, Profitability, and Soil Well-Being. Front. Sustain. Food Syst. 2023, 7, 1260178. [Google Scholar] [CrossRef]
  157. Mustafa, M.; Azam, M.; Nawaz Bhatti, H.; Khan, A.; Zafar, L.; Rehan Abbasi, A.M. Green Fabrication of Copper Nano-Fertilizer for Enhanced Crop Yield in Cowpea Cultivar: A Sustainable Approach. Biocatal. Agric. Biotechnol. 2024, 56, 102994. [Google Scholar] [CrossRef]
  158. Jha, A.; Pathania, D.; Sonu; Damathia, B.; Raizada, P.; Rustagi, S.; Singh, P.; Rani, G.M.; Chaudhary, V. Panorama of Biogenic Nano-Fertilizers: A Road to Sustainable Agriculture. Environ. Res. 2023, 235, 116456. [Google Scholar] [CrossRef]
  159. Francis, D.V.; Sood, N.; Gokhale, T. Biogenic CuO and ZnO Nanoparticles as Nanofertilizers for Sustainable Growth of Amaranthus Hybridus. Plants 2022, 11, 2776. [Google Scholar] [CrossRef] [PubMed]
  160. Murali, M.; Gowtham, H.G.; Shilpa, N.; Singh, S.B.; Aiyaz, M.; Sayyed, R.Z.; Shivamallu, C.; Achar, R.R.; Silina, E.; Stupin, V.; et al. Zinc Oxide Nanoparticles Prepared through Microbial Mediated Synthesis for Therapeutic Applications: A Possible Alternative for Plants. Front. Microbiol. 2023, 14, 1227951. [Google Scholar] [CrossRef] [PubMed]
  161. Mahawar, L.; Ramasamy, K.P.; Suhel, M.; Prasad, S.M.; Živčák, M.; Brestic, M.; Rastogi, A.; Skalický, M. Silicon Nanoparticles: Comprehensive Review on Biogenic Synthesis and Applications in Agriculture. Environ. Res. 2023, 232, 116292. [Google Scholar] [CrossRef]
  162. Priyam, A.; Yadav, N.; Reddy, P.M.; Afonso, L.O.B.; Schultz, A.G.; Singh, P.P. Fertilizing Benefits of Biogenic Phosphorous Nanonutrients on Solanum Lycopersicum in Soils with Variable pH. Heliyon 2022, 8, e09144. [Google Scholar] [CrossRef]
  163. Guilger-Casagrande, M.; Bilesky-José, N.; Sousa, B.T.; Oliveira, H.C.; Fraceto, L.F.; Lima, R. Effects of Biogenic Silver and Iron Nanoparticles on Soybean Seedlings (Glycine max). BMC Plant Biol. 2022, 22, 255. [Google Scholar] [CrossRef] [PubMed]
  164. Nguyen, N.T.T.; Nguyen, L.M.; Nguyen, T.T.T.; Tran, U.P.N.; Nguyen, D.T.C.; Tran, T.V. A Critical Review on the Bio-Mediated Green Synthesis and Multiple Applications of Magnesium Oxide Nanoparticles. Chemosphere 2023, 312, 137301. [Google Scholar] [CrossRef] [PubMed]
  165. Yadav, R.; Kumar, M.; Tomar, R.S. Cyanobacteria Based Nanoformulation of Biogenic CuO Nanoparticles for Plant Growth Promotion of Rice Under Hydroponics Conditions. Curr. Microbiol. 2024, 81, 118. [Google Scholar] [CrossRef] [PubMed]
  166. Malik, K.; Mandhania, S.; Anil; Arya, S.; Dhaka, A.; Ravikant; Kumari, N.; Malik, K.; Priyanka; Kumar, U. Organic Farming and Bio-Nanomaterial Conflux: A Way Forward for Sustainable Agriculture. J. Nanosci. Nanotechnol. 2021, 21, 3379–3393. [Google Scholar] [CrossRef] [PubMed]
  167. Azameti, M.K.; Imoro, A.-W.M. Nanotechnology: A Promising Field in Enhancing Abiotic Stress Tolerance in Plants. Crop Des. 2023, 2, 100037. [Google Scholar] [CrossRef]
  168. Dhiman, S.; Yadav, A.; Debnath, N.; Das, S. Application of Core/Shell Nanoparticles in Smart Farming: A Paradigm Shift for Making the Agriculture Sector More Sustainable. J. Agric. Food Chem. 2021, 69, 3267–3283. [Google Scholar] [CrossRef] [PubMed]
  169. Seliem, M.K.; Hafez, Y.; El-Ramady, H. Using of Nano—Selenium in Reducing the Negative Effects of High Temperature Stress on Chrysanthemum Morifolium Ramat. J. Sustain. Agric. Sci. 2020, 46, 47–60. [Google Scholar] [CrossRef]
  170. Iqbal, M.; Raja, N.I.; Mashwani, Z.-U.-R.; Hussain, M.; Ejaz, M.; Yasmeen, F. Effect of Silver Nanoparticles on Growth of Wheat Under Heat Stress. Iran. J. Sci. Technol. Trans. Sci. 2019, 43, 387–395. [Google Scholar] [CrossRef]
  171. Djanaguiraman, M.; Belliraj, N.; Bossmann, S.H.; Prasad, P.V.V. High-Temperature Stress Alleviation by Selenium Nanoparticle Treatment in Grain Sorghum. ACS Omega 2018, 3, 2479–2491. [Google Scholar] [CrossRef]
  172. Wu, J.; Wang, T. Synergistic Effect of Zinc Oxide Nanoparticles and Heat Stress on the Alleviation of Transcriptional Gene Silencing in Arabidopsis Thaliana. Bull. Environ. Contam. Toxicol. 2020, 104, 49–56. [Google Scholar] [CrossRef]
  173. Thakur, S.; Asthir, B.; Kaur, G.; Kalia, A.; Sharma, A. Zinc Oxide and Titanium Dioxide Nanoparticles Influence Heat Stress Tolerance Mediated by Antioxidant Defense System in Wheat. Cereal Res. Commun. 2022, 50, 385–396. [Google Scholar] [CrossRef]
  174. Wu, H.; Tito, N.; Giraldo, J.P. Anionic Cerium Oxide Nanoparticles Protect Plant Photosynthesis from Abiotic Stress by Scavenging Reactive Oxygen Species. ACS Nano 2017, 11, 11283–11297. [Google Scholar] [CrossRef] [PubMed]
  175. Hallaji, B.; Haghighi, M.; Abolghasemi, R.; Mozafarian, M. Effect of Foliar Applications of Aminolevulinic Acid (Bulk and Nano-Encapsulated) on Bell Pepper under Heat Stress. Plant Stress 2024, 12, 100477. [Google Scholar] [CrossRef]
  176. Preetha, J.S.Y.; Sriram, D.; Premasudha, P.; Pudake, R.N.; Arun, M. Cerium Oxide as a Nanozyme for Plant Abiotic Stress Tolerance: An Overview of the Mechanisms. Plant Nano Biol. 2023, 6, 100049. [Google Scholar] [CrossRef]
  177. Younis, A.A.; Khattab, H.; Emam, M.M. Impacts of Silicon and Silicon Nanoparticles on Leaf Ultrastructure and TaPIP1 and TaNIP2 Gene Expressions in Heat Stressed Wheat Seedlings. Biol. Plant. 2020, 64, 343–352. [Google Scholar] [CrossRef]
  178. Sidhu, A.K.; Sharma, M.; Agrawal, S.B.; Bhavsar, P.; Samota, M.K. Nanomaterial strategies for enhancing plant resilience in the face of temperature stress. CABI Agric. Biosci. 2024, 5, 60. [Google Scholar] [CrossRef]
  179. Sheikh, Z.N.; Raina, S.; Bhat, U.H.; Sharma, N.; Saffeullah, P.; Mohammad, F.; Al-Andal, A.; Islam, S. Deciphering the potential role of nano-based biosensors in growth, development and stress management of crop plants. South Afr. J. Bot. 2024, 167, 542–553. [Google Scholar] [CrossRef]
  180. Victoria, J.; Tripathi, S.; Prakash, V.; Tiwari, K.; Mahra, S.; Sharma, A.; Rana, S.; Kandhol, N.; Sahi, S.; Tripathi, D.K.; et al. Encapsulated Nanopesticides Application in Plant Protection: Quo Vadis? Plant Physiol. Biochem. 2024, 206, 108225. [Google Scholar] [CrossRef]
  181. Brevik, E.C.; Slaughter, L.; Singh, B.R.; Steffan, J.J.; Collier, D.; Barnhart, P.; Pereira, P. Soil and Human Health: Current Status and Future Needs. Air Soil Water Res. 2020, 13, 117862212093444. [Google Scholar] [CrossRef]
  182. Li, X.; Chen, Y.; Xu, J.; Lynch, I.; Guo, Z.; Xie, C.; Zhang, P. Advanced Nanopesticides: Advantage and Action Mechanisms. Plant Physiol. Biochem. 2023, 203, 108051. [Google Scholar] [CrossRef]
  183. Liu, K.; Liu, X.; Chen, J.; Wang, X.; Zhang, W. A Study on the Pesticides-Loading Capacity of Dendritic Fibrous Nano Silica Synthesized from 1-Pentanol-Water Microemulsion with a Low Oil-Water Ratio. Nanotechnology 2023, 34, 415701. [Google Scholar] [CrossRef]
  184. Laudani, F.; Campolo, O.; Caridi, R.; Latella, I.; Modafferi, A.; Palmeri, V.; Sorgonà, A.; Zoccali, P.; Giunti, G. Aphicidal Activity and Phytotoxicity of Citrus Sinensis Essential-Oil-Based Nano-Insecticide. Insects 2022, 13, 1150. [Google Scholar] [CrossRef] [PubMed]
  185. Del Prado-Audelo, M.L.; Bernal-Chávez, S.A.; Gutiérrez-Ruíz, S.C.; Hernández-Parra, H.; Kerdan, I.G.; Reyna-González, J.M.; Sharifi-Rad, J.; Leyva-Gómez, G. Stability Phenomena Associated with the Development of Polymer-Based Nanopesticides. Oxid. Med. Cell. Longev. 2022, 2022, 5766199. [Google Scholar] [CrossRef] [PubMed]
  186. Wu, J.; Chang, J.; Liu, J.; Huang, J.; Song, Z.; Xie, X.; Wei, L.; Xu, J.; Huang, S.; Cheng, D.; et al. Chitosan-Based Nanopesticides Enhanced Anti-Fungal Activity against Strawberry Anthracnose as “Sugar-Coated Bombs”. Int. J. Biol. Macromol. 2023, 253, 126947. [Google Scholar] [CrossRef]
  187. Rani, N.; Duhan, A.; Pal, A.; Kumari, P.; Beniwal, R.K.; Verma, D.; Goyat, A.; Singh, R. Are Nano-Pesticides Really Meant for Cleaner Production? An Overview on Recent Developments, Benefits, Environmental Hazards and Future Prospectives. J. Clean. Prod. 2023, 411, 137232. [Google Scholar] [CrossRef]
  188. Mittal, D.; Kaur, G.; Singh, P.; Yadav, K.; Ali, S.A. Nanoparticle-Based Sustainable Agriculture and Food Science: Recent Advances and Future Outlook. Front. Nanotechnol. 2020, 2, 579954. [Google Scholar] [CrossRef]
  189. Zhang, J.; Kothalawala, S.; Yu, C. Engineered Silica Nanomaterials in Pesticide Delivery: Challenges and Perspectives. Environ. Pollut. 2023, 320, 121045. [Google Scholar] [CrossRef]
  190. Fatima, H.; Hamdani, S.D.A.; Ahmed, M.; Rajput, T.A.; Gul, A.; Amir, R.; Munir, F.; Malik, S.Z.; Babar, M.M. Anti-MRSA Potential of Biogenic Silver Nanoparticles Synthesized from Hydroponically Grown Foeniculum Vulgare. Phytomedicine Plus 2023, 3, 100415. [Google Scholar] [CrossRef]
  191. Kim, D.-Y.; Patel, S.K.S.; Rasool, K.; Lone, N.; Bhatia, S.K.; Seth, C.S.; Ghodake, G.S. Bioinspired Silver Nanoparticle-Based Nanocomposites for Effective Control of Plant Pathogens: A Review. Sci. Total Environ. 2024, 908, 168318. [Google Scholar] [CrossRef]
  192. Warghane, A.; Saini, R.; Shri, M.; Andankar, I.; Ghosh, D.K.; Chopade, B.A. Application of Nanoparticles for Management of Plant Viral Pathogen: Current Status and Future Prospects. Virology 2024, 592, 109998. [Google Scholar] [CrossRef]
  193. Gao, Y.; Xiao, Y.; Mao, K.; Qin, X.; Zhang, Y.; Li, D.; Zhang, Y.; Li, J.; Wan, H.; He, S. Thermoresponsive Polymer-Encapsulated Hollow Mesoporous Silica Nanoparticles and Their Application in Insecticide Delivery. Chem. Eng. J. 2020, 383, 123169. [Google Scholar] [CrossRef]
  194. Tang, J.; Tong, X.; Chen, Y.; Wu, Y.; Zheng, Z.; Kayitmazer, A.B.; Ahmad, A.; Ramzan, N.; Yang, J.; Huang, Q.; et al. Deposition and Water Repelling of Temperature-Responsive Nanopesticides on Leaves. Nat. Commun. 2023, 14, 6401. [Google Scholar] [CrossRef]
  195. Shen, M.; Liu, S.; Jiang, C.; Zhang, T.; Chen, W. Recent Advances in Stimuli-Response Mechanisms of Nano-Enabled Controlled-Release Fertilizers and Pesticides. Eco-Environ. Health 2023, 2, 161–175. [Google Scholar] [CrossRef]
  196. Lin, H.; Ma, N.; He, L.; Xu, P.; Wang, F.; You, C. High Deposition and Precise Stimulus-Response Release Performance of Lignin-Coated Dendritic Mesoporous Organosilica Nanoparticles for Efficient Pesticide Utilization. Int. J. Biol. Macromol. 2024, 259, 129163. [Google Scholar] [CrossRef] [PubMed]
  197. Chai, A.; Yuan, L.; Li, X.; Li, L.; Shi, Y.; Xie, X.; Li, B. Effect of Temperature and Humidity on Dynamics and Transmission of Pseudomonas Amygdali Pv. Lachrymans Aerosols. Front. Plant Sci. 2023, 14, 1087496. [Google Scholar] [CrossRef] [PubMed]
  198. Roussin-Léveillée, C.; Rossi, C.A.M.; Castroverde, C.D.M.; Moffett, P. The Plant Disease Triangle Facing Climate Change: A Molecular Perspective. Trends Plant Sci. 2024, S1360138524000608. [Google Scholar] [CrossRef] [PubMed]
  199. Taha, N.A.; Hamden, S.; Bayoumi, Y.A.; Elsakhawy, T.; El-Ramady, H.; Solberg, S.Ø. Nanofungicides with Selenium and Silicon Can Boost the Growth and Yield of Common Bean (Phaseolus vulgaris L.) and Control Alternaria Leaf Spot Disease. Microorganisms 2023, 11, 728. [Google Scholar] [CrossRef]
  200. Liu, Y.; Zhang, Y.; Xin, X.; Xu, X.; Wang, G.; Gao, S.; Qiao, L.; Yin, S.; Liu, H.; Jia, C.; et al. Design and Preparation of Avermectin Nanopesticide for Control and Prevention of Pine Wilt Disease. Nanomaterials 2022, 12, 1863. [Google Scholar] [CrossRef]
  201. Siddiqui, Z.A.; Khan, A.; Khan, M.R.; Abd-Allah, E.F. Effects of Zinc Oxide Nanoparticles (ZnO NPs) and Some Plant Pathogens on the Growth and Nodulation of Lentil (Lens culinaris Medik.). Acta Phytopathol. Entomol. Hung. 2018, 53, 195–211. [Google Scholar] [CrossRef]
  202. Ogunyemi, S.O.; Abdallah, Y.; Zhang, M.; Fouad, H.; Hong, X.; Ibrahim, E.; Masum, M.M.I.; Hossain, A.; Mo, J.; Li, B. Green Synthesis of Zinc Oxide Nanoparticles Using Different Plant Extracts and Their Antibacterial Activity against Xanthomonas Oryzae Pv. Oryzae. Artif. Cells Nanomed. Biotechnol. 2019, 47, 341–352. [Google Scholar] [CrossRef]
  203. Khan, M.; Khan, A.U.; Bogdanchikova, N.; Garibo, D. Antibacterial and Antifungal Studies of Biosynthesized Silver Nanoparticles against Plant Parasitic Nematode Meloidogyne Incognita, Plant Pathogens Ralstonia Solanacearum and Fusarium Oxysporum. Molecules 2021, 26, 2462. [Google Scholar] [CrossRef]
  204. Cheng, H.-J.; Wang, H.; Zhang, J.-Z. Phytofabrication of Silver Nanoparticles Using Three Flower Extracts and Their Antibacterial Activities Against Pathogen Ralstonia Solanacearum Strain YY06 of Bacterial Wilt. Front. Microbiol. 2020, 11, 2110. [Google Scholar] [CrossRef]
  205. Dilbar, S.; Sher, H.; Ali, H.; Ullah, R.; Ali, A.; Ullah, Z. Antibacterial Efficacy of Green Synthesized Silver Nanoparticles Using Salvia Nubicola Extract against Ralstonia Solanacearum, the Causal Agent of Vascular Wilt of Tomato. ACS Omega 2023, 8, 31155–31167. [Google Scholar] [CrossRef]
  206. Zaki, A.G.; Hasanien, Y.A.; El-Sayyad, G.S. Novel Fabrication of SiO2/Ag Nanocomposite by Gamma Irradiated Fusarium Oxysporum to Combat Ralstonia Solanacearum. AMB Express 2022, 12, 25. [Google Scholar] [CrossRef]
  207. Malandrakis, A.A.; Kavroulakis, N.; Chrysikopoulos, C.V. Use of Copper, Silver and Zinc Nanoparticles against Foliar and Soil-Borne Plant Pathogens. Sci. Total Environ. 2019, 670, 292–299. [Google Scholar] [CrossRef]
  208. Lakshmeesha, T.R.; Kalagatur, N.K.; Mudili, V.; Mohan, C.D.; Rangappa, S.; Prasad, B.D.; Ashwini, B.S.; Hashem, A.; Alqarawi, A.A.; Malik, J.A.; et al. Biofabrication of Zinc Oxide Nanoparticles With Syzygium Aromaticum Flower Buds Extract and Finding Its Novel Application in Controlling the Growth and Mycotoxins of Fusarium Graminearum. Front. Microbiol. 2019, 10, 1244. [Google Scholar] [CrossRef]
  209. Kalia, A.; Kaur, J.; Kaur, A.; Singh, N. Antimycotic Activity of Biogenically Synthesised Metal and Metal Oxide Nanoparticles against Plant Pathogenic Fungus Fusarium Moniliforme (F. Fujikuroi). Indian J. Exp. Biol. 2020, 58, 263–270. [Google Scholar] [CrossRef]
  210. Derbalah, A.; Shenashen, M.; Hamza, A.; Mohamed, A.; El Safty, S. Antifungal Activity of Fabricated Mesoporous Silica Nanoparticles against Early Blight of Tomato. Egypt. J. Basic Appl. Sci. 2018, 5, 145–150. [Google Scholar] [CrossRef]
  211. Youssef, K.; De Oliveira, A.G.; Tischer, C.A.; Hussain, I.; Roberto, S.R. Synergistic Effect of a Novel Chitosan/Silica Nanocomposites-Based Formulation against Gray Mold of Table Grapes and Its Possible Mode of Action. Int. J. Biol. Macromol. 2019, 141, 247–258. [Google Scholar] [CrossRef] [PubMed]
  212. Cai, L.; Liu, C.; Fan, G.; Liu, C.; Sun, X. Preventing Viral Disease by ZnONPs through Directly Deactivating TMV and Activating Plant Immunity in Nicotiana benthamiana. Environ. Sci. Nano 2019, 6, 3653–3669. [Google Scholar] [CrossRef]
  213. Chaud, M.; Souto, E.B.; Zielinska, A.; Severino, P.; Batain, F.; Oliveira-Junior, J.; Alves, T. Nanopesticides in Agriculture: Benefits and Challenge in Agricultural Productivity, Toxicological Risks to Human Health and Environment. Toxics 2021, 9, 131. [Google Scholar] [CrossRef]
  214. Grillo, R.; Fraceto, L.F.; Amorim, M.J.B.; Scott-Fordsmand, J.J.; Schoonjans, R.; Chaudhry, Q. Ecotoxicological and Regulatory Aspects of Environmental Sustainability of Nanopesticides. J. Hazard. Mater. 2021, 404, 124148. [Google Scholar] [CrossRef] [PubMed]
  215. Maity, D.; Gupta, U.; Saha, S. Biosynthesized Metal Oxide Nanoparticles for Sustainable Agriculture: Next-Generation Nanotechnology for Crop Production, Protection and Management. Nanoscale 2022, 14, 13950–13989. [Google Scholar] [CrossRef] [PubMed]
Nanomaterials 14 01253 g001
Figure 1. An overview of nano-agrochemicals, including definition, main groups, factors controlling the release of these compounds, benefits, and ecological risks. Abbreviations: NPs—nanoparticles and NMs—nanomaterials.
Figure 1. An overview of nano-agrochemicals, including definition, main groups, factors controlling the release of these compounds, benefits, and ecological risks. Abbreviations: NPs—nanoparticles and NMs—nanomaterials.
Nanomaterials 14 01253 g001
Nanomaterials 14 01253 g006
Figure 6. Advantages of nanopesticides (NPts) as compared to traditional pesticides. Examples of NPts are presented in the yellow boxes. Source: [182].
Figure 6. Advantages of nanopesticides (NPts) as compared to traditional pesticides. Examples of NPts are presented in the yellow boxes. Source: [182].
Nanomaterials 14 01253 g006
Table 2. Impacts of combined salinity and heat stress on crops in the presence and absence of antistressors.
Table 2. Impacts of combined salinity and heat stress on crops in the presence and absence of antistressors.
Plant SpeciesStress Conditions (Heat and Salinity)Applied Antistressors (ASs)Main Findings Refs.
Cucumber (Cucumis sativus L.)Heat stress (41 °C); salinity stress (EC 4.49 dS m−1)Nano-Se (25 mg L−1), silicon (Si, 200 mg L−1)Applied nano-Se and Si promoted plant growth and yield under stress by controlling stomatal opening and regulating the osmotic balance [64]
Soybean (Glycine max L.)Heat pre-treatment of seeds (45 °C), salt stress (sea water (diluted by 1/12 and 1/6) SiO2-NPs (1 mM; 50 nm) and nano-Se (20 ppm; 40 nm)Heat pre-treated seeds in the presence of nano-antistressors ameliorated salt-stress and recovery against oxidative stress[102]
Oregano (Origanum vulgare L.)Heat (27 °C), salt stress (50, 75, 100, 150, 175 mM NaCl) SA (1 mM), GABA (0.5, 0.7, 1.0, 1.5 and 2.0 mM)Applied SA and GABA compounds protected plants under stress by regulation of secondary metabolites and enzyme-pigments [33]
Cherry tomato (Solanum lycopersicum L.) Salt stress (100 mM NaCl) and heat (42 °C; 4 h/day)Without-ASs (seedlings were grown in pots for 21 days in a growth chamber)Combined stresses negatively impacted growth and photosynthetic pigments more than individual stresses, transcript accumulation and protein content depleted in stressed plants, reduced carbon assimilation [108]
Rice (Oryza sativa L.) Heat (31 °C) and salinity stress (75 mM NaCl)Without-ASs (seedlings were studied under seedling, vegetative and reproductive stage)Stress greatly reduced plant growth performance and yield. Heat stress did not impact yield during reproduction but reduced grain quality[34]
Peppermint (Mentha piperita L.)Salt stress at 60 and 120 mM NaCl and heat stress at 35 °CWithout-ASs (seedlings were grown in pots filled with soil, sand, manure and vermicompost in a ratio of 1:1:1:2, resp.)Rosmarinic acid, soluble sugar, chlorophyll and K+/N+ decreased by 3.2, 1.8, 4.6 and 9 times after 72 h respectively at 35 °C and salt stress of 120 mM [109]
White goosefoot (Chenopodium album L.)Salt stress (100 and 300 mM diluted from sea water), heat (shaded and non-shaded plots)Without-ASs (seedlings were grown under field conditions for 60 days)Combined stresses had negative impacts on studied plants, shading improved plant tolerance to salinity and alleviated heat and drought stresses[110]
Rice (Oryza sativa L.)Soil salinity was 20 dS m−1), heat stress (35 °C/26 °C for day/night cycle)Without-ASs (14 day old seedlings were grown in a growth chamber in pots)Combined stress formed CAT, APX, SOD with rapid readjustment at the molecular and physiological levels[111]
Rice (Oryza sativa L.) Heat (30 °C), salt stress (75 mM NaCl) Without-ASs (seedlings were grown in a hydroponic system for 14 days)Under combined stress, specific genes can show molecular response along with physiological and metabolic mechanisms[112]
Abbreviations: salicylic acid (SA), gamma-aminobutyric acid (GABA), catalase activity (CAT), superoxide dismutase (SOD), and ascorbate peroxidase (APX).
Table 4. Impacts of applied nanofertilizers or nanomaterials on plants under heat stress.
Table 4. Impacts of applied nanofertilizers or nanomaterials on plants under heat stress.
Plant SpeciesNano-Based Nutrient Dose(s)Nanofertilizer Synthesis (Size)Heat-Stress DetailsMain EffectsRefs.
Alfalfa (Medicago sativa L.) ZnO-NPs (30, 60, 90 ppm) Chemical (10–20 nm)45 and 34 °C
day/nighttime for 7 d		Pre-treatment seedlings
alleviated heat stress by reducing ultrastructural damages (chloroplast, mitochondria, and cell wall)		[152]
Mung bean (Vigna radiata L.)ZnO-NPs (15, 30, 45, and 60 ppm)Chemical (20 nm)40/25 °C day/night for 3 monthsUp-streamed production of osmolytes and antioxidants to attenuate the shocks of heat stress[146]
Chrysanthemum morifolium RamatNano-Se (50, 100, 150 and 200 ppm)Biological (50–200 nm)37.3 to 41.6 °C for 3 monthsImproved the antioxidant system, floral quality, and attributes[169]
Wheat (Triticum aestivum L.)Nano-Se (50, 75, and 100 ppm)Biological (56–88 nm)Heat stress (temperature not reported)Reduced the incidence of wheat crown and root rot diseases, enhanced plant growth, and grain quality[25]
Wheat (Triticum aestivum L.)Ag-NPs (25, 50, 75 and 100 ppmGreen (34 nm)35–40 °C for 3 h/day for about 3 daysProtected plants against heat stress through ROS and antioxidant defense[170]
Sorghum (Sorghum bicolor L. Moench)Se-NPs (100, 250, and 500 ppm) for 48 h Chemical (10–40 nm)38/28 °C (day/night) for 10 daysImproved germination of pollen, antioxidant activity, and increased seed yield[171]
Arabidopsis thaliana L.ZnO-NPs (0.1, 0.5 and 1 ppm)Chemical (20 nm)37 °C for 3 h Enhanced the alleviation of heat stress by inducing transcriptional gene silencing/β-glucuronidase[172]
Wheat (Triticum aestivum L.) ZnO-NPs (1.5 and 10 ppm)Chemical (25 nm)32 °C for 12 daysImproved antioxidants, membrane stability, and reduced MDA and H2O2 content at 1.5 ppm[173]
Wheat (Triticum aestivum L.)Nano-sized chitosan-glycine-betaine (100 mM) for 18 hNanocomposite 37/28 ± 2 °C (day/night) for 14 daysIncreased the activities of antioxidants, which aided in scavenging the stress-induced oxidative damages[153]
Arabidopsis thaliana L.Cerium oxide NPs (nanoceria)Poly(acrylic acid) nanoceria (10.3 nm), multiple ways to synthesize35 °C for 2.5 hReduced ROS, oxidative damage, and improved photosynthesis and carbon assimilation[174]
Bell pepper (Capsicum annum L.)Nano-encapsules of amino levulinic acid Nano-encapsulation (78 to 94 nm)at 35 °C for 6 h Increased antioxidant enzymes (POD, SOD, and CAT) and proline levels under heat stress conditions[175]
Abbreviations: malonaldehyde (MDA), reactive oxygen species (ROS), peroxidase (POD), superoxide dismutase (SOD), and catalase (CAT).
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Prokisch, J.; Ferroudj, A.; Labidi, S.; El-Ramady, H.; Brevik, E.C. Biological Nano-Agrochemicals for Crop Production as an Emerging Way to Address Heat and Associated Stresses. Nanomaterials 2024, 14, 1253. https://doi.org/10.3390/nano14151253

AMA Style

Prokisch J, Ferroudj A, Labidi S, El-Ramady H, Brevik EC. Biological Nano-Agrochemicals for Crop Production as an Emerging Way to Address Heat and Associated Stresses. Nanomaterials. 2024; 14(15):1253. https://doi.org/10.3390/nano14151253

Chicago/Turabian Style

Prokisch, József, Aya Ferroudj, Safa Labidi, Hassan El-Ramady, and Eric C. Brevik. 2024. "Biological Nano-Agrochemicals for Crop Production as an Emerging Way to Address Heat and Associated Stresses" Nanomaterials 14, no. 15: 1253. https://doi.org/10.3390/nano14151253

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Article metric data becomes available approximately 24 hours after publication online.
Back to TopTop