Chemoinformatics Analysis of the Colour Fastness Properties of Acid and Direct Dyes in Textile Coloration
Round 1
Reviewer 1 Report
In this manuscript, the chemoinformatics analysis is used to discuss the chemical structure/property relationships of acid and direct dyes which deal with several cases: the light fastness of acid dyes on wool and polyamide fibers, the sensitivity of acid dyes on wool to oxygen bleaching, the wash fastness of acid dyes on wool, the adsorption of direct dyes on cotton. The important and interesting results are achieved. The conclusions are supported by the data. This research is a good attempt to predict the color fastness and adsorption properties of dyes, which is helpful in designing the chemical structure of dyes. After minor revisions, this manuscript can be accepted for publishing.
Special suggestions:
Please note the use of the definite article “the”.
English writing should be carefully checked and improved.
Abstract Section:
Line 11: “dyings” should be replaced by “dyeings”.
Lines 13-14: “wash fastness of acid dyes on wool and adsorption of direct dyes on cotton” should be replaced by “the wash fastness of acid dyes on wool and the adsorption of direct dyes on cotton”.
Line 15: “depicts the contribution” should be replaced by “depicted the contribution”.
Introduction Section:
Line 26: “was essential of” should be replaced by “was an essential of” or “was essential for”.
Line 42: “acid dyes for wool and Nylon [18], disperse dyes for synthetic fibres” should be replaced by “acid dyes for wool and nylon [18], and disperse dyes for synthetic fibres”.
Line 55: “, another one” should be replaced by “, and another one”.
Line 66: “The analysis of the chemical structure and property relationships usually apply” should be replaced by “The analysis --- usually applies”.
Materials and Methods Section:
Line 102: “Database for light fastness of research acid azo dyes on polyamide fibres (Nylon 6.6)”: This description should be improved.
Results and Discussion Section:
Lines 143-145: “The sign of the regression coefficient characterises ---, the absolute value of the coefficient shows ---”: This description should be improved. For example: “, and the absolute value --- shows ---”
Line 143 “characterises”, Line 146 “characterizes”: Please use one English (UK or American English).
Lines: 195-196: “In our case wash fastness reflects the intermolecular bonding of acid dyes with wool composed from keratin and lipids”: I suggest to delete “and lipids” because they are deleted in the pretreatment (scouring) before dyeing.
Regarding Figure 5, the indicator used is dye exhaustion (%)? or the amount of dye adsorption (g dye/kg fiber, mg dye/g fiber)? Please mention it in the text.
Author Response
Dear Editor, and Reviewers
Please find our responses in the attached PDF. Thank you.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Dear Sirs,
My recommendation is acceptance for publication because this paper presents a study of the application of a universal method of calculating the influence of atomic fragments without any reference to the physicochemical properties of the molecule, which satisfies the clear understanding of chemists and provides a simple interpretation of results useful for developing different chemical and physicochemical properties of dyed fabrics.
Each dyestuff base investigated is characterized by multiple linear regression models with substructural fragments describing fiber color sorption, wash resistance, and light fastness of anionic dyes adsorbed on cotton, wool, and polyamide fibers.
The results indicate the corresponding mechanisms of physicochemical destruction of dyes in the tests of resistance to light and adsorption / desorption in the tests of resistance to washing and staining.
Precisely such research significantly contributes to the wider scientific community, but also to the economy in the application of textile dyes.
Author Response
Dear Editor, and Reviewers
We are pleased to submit a revised manuscript for your consideration.
We are grateful for the careful review of the manuscript and all the suggestions for the revision. All the recommendations are highly appreciated and agreed upon by the authors.
In general, the revisions are concerned with the careful checking of the language.
The order of authors is changed. The supervisor of the research, Prof. Telegin, is placed at the end of the list.
Several additions are made:
- New references;
- Section 3.6. Photodegradation of azo dyes in solution;
- A reference to the funding: This work received financial support from the Ministry of Science and Higher Education 343 of the Russian Federation (No. 075-15-2021-579).
The changes and additions are highlighted in yellow.
Reviewer 3 Report
The manuscript could be interesting for a scientific audience.
The manuscript needs minor revision:
- Please check all language and typing errors.
- The introduction needs to be enriched. Why did you choose the dyes, fibres and properties?
- In the introduction “describing dye sorption by fibres, wash fastness and lightfastness of anionic dyes adsorbed on cotton, wool and polyamide fibres.” The study examined only the Lightfastness of acid dyes on polyamide (Nylon) fibres and direct dye absorption of cotton. Why didn`t study Wash fastness, dye absorption and Colour fastness to oxygen bleaching of azo dye on polyamide and cotton?
- I think the discussion of the results needs more explanation.
Author Response
Dear Editor, and Reviewers
Please find our responses in the attached PDF. Thank you.
Author Response File: Author Response.pdf
Reviewer 4 Report
Dear Authors:
Chemoinformatics is important, however, I find it hard to relate this with the textile examples. Textile coloration is a complex process and varies with a slight change during dyeing. Same dye would perform different result on the same fabric if there has been a minor modification during the pretreatment. Therefore, relating different studies for different fastness test and then relating it with each other is out of question.
What is the significance of the study?
Why the data base is important?
Why only acid and direct dyes were focused when cotton is dyed usually using reactive dyes?
Literature is very outdated.
Author Response
Dear Editor, and Reviewers,
Please find our responses in the attached PDF. Thank you.
Author Response File: Author Response.pdf
Reviewer 5 Report
in this work, the authors reported on the efficiency of chemoinformatics methods based on fragment approach for analysis the 10 relationships between the chemical structure of textile dyes and colour fastness of dyings have been 11 shown by examining a large set of properties, including the light fastness of acid dyes on wool and 12 polyamide fibres, the sensitivity of acid dyes on wool to oxygen bleaching, wash fastness of acid 13 dyes on wool and adsorption of direct dyes on cotton.
the manuscript was written in a clear scientific manner and results were supported by necessary investigating tools as well as statical analysis.
i recommend acceptance
Author Response
Dear Editor, and Reviewers
We are pleased to submit a revised manuscript for your consideration.
We are grateful for the careful review of the manuscript and all the suggestions for the revision. All the recommendations are highly appreciated and agreed upon by the authors.
In general, the revisions are concerned with the careful checking of the language.
The order of authors is changed. The supervisor of the research, Prof. Telegin, is placed at the end of the list.
Several additions are made:
- New references;
- Section 3.6. Photodegradation of azo dyes in solution;
- A reference to the funding: This work received financial support from the Ministry of Science and Higher Education 343 of the Russian Federation (No. 075-15-2021-579).
The changes and additions are highlighted in yellow.
Round 2
Reviewer 4 Report
My recommendation is acceptance for publication in present form.
