The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Population
2.2. Recruitment and Study Participants
2.2.1. Data on Maternal Smoking
2.2.2. Anthropometric Assessment of the Newborn
2.3. Maternal Urinary Cotinine Collection and Measurement
2.4. Statistical Analysis
3. Results
3.1. Maternal Demographics and Urine Cotinine Analysis
3.2. Cotinine Exposure on Anthropometric Measurements of the Newborn
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Non-Smokers (N = 200) | Smokers (N = 38) | p-Value | |
---|---|---|---|
Mean (SD) maternal age (years) | 29.5 (6.0) | 29.2 (6.3) | 0.793 |
Mean (SD) maternal BMI (kg/mL) | 28.8 (7.3) | 27.0 (7.5) | 0.274 |
Mode of birth (SVB/Other) (N) | 122/78 | 22/16 | 0.591 |
History of alcohol consumption (%/N) | 5.5 (11) | 0 | 0.362 |
Other recreational drug use (%/N) | 7.5 (15) | 5.3 (2) | 1.000 |
Maternal diagnosis of eclampsia (%/N) | 5.5 (11) | 5.3 (2) | 1.000 |
Maternal diagnosis of DM/GDM (%/N) | 31.5 (63) | 34.2 (13) | 0.851 |
Neonatal Variables | Maternal Urine Cotinine Not Detected | Maternal Urine Cotinine Detected | p |
---|---|---|---|
Birth weight (g (SD)) | 3458 (464) | 3293 (519) | 0.010 |
Birth weight Z score (SD) | 0.17 (0.93) | −0.16 (1.04) | 0.010 |
Head circumference (cm (SD)) | 34.9 (1.2) | 34.7 (1.7) | 0.204 |
Length (cm (SD)) | 50.4 (2.3) | 49.8 (3.0) | 0.074 |
Gestation (weeks (SD)) | 39.0 (1.1) | 38.8 (2.0) | 0.223 |
Female/Male (N) | 64/54 | 52/68 | 0.093 |
SGA/AGA (N) | 3/115 | 13/107 | 0.011 |
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Vojisavljevic, D.; Rudd, D.; Smith, R.; Kandasamy, Y. The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies. Children 2024, 11, 1028. https://doi.org/10.3390/children11081028
Vojisavljevic D, Rudd D, Smith R, Kandasamy Y. The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies. Children. 2024; 11(8):1028. https://doi.org/10.3390/children11081028
Chicago/Turabian StyleVojisavljevic, Danica, Donna Rudd, Roger Smith, and Yogavijayan Kandasamy. 2024. "The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies" Children 11, no. 8: 1028. https://doi.org/10.3390/children11081028