Neonatal and Maternal 25-OH Vitamin D Serum Levels in Neonates with Early-Onset Sepsis
Abstract
:1. Introduction
2. Patients and Methods
2.1. Patients
2.2. Controls
2.3. Laboratory Investigations
2.4. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Item | Full-term (n = 40) | Preterm (n = 40) | |||||
---|---|---|---|---|---|---|---|
Patients (n = 25) | Control (n = 15) | p-value | Patients (n = 25) | Control (n = 15) | p-value | ||
Gestational age (weeks) | Mean ± SD | 37.5 ± 0.98 | 37.4 ± 0.58 | 0.08 | 34.1 ± 1.26 | 35.2 ± 2.14 | 0.15 |
Birth weight (kg) | Mean ± SD | 3.2 ± 0.43 | 3.19 ± 0.35 | 0.08 | 2.78 ± 0.3 | 2.14 ± 0.26 | 0.06 |
Gender | Male Female | 14 (56%) 11 (44%) | 12 (80%) 3 (20%) | 0.19 | 15 (60%) 10 (40%) | 8 (53%) 7 (47%) | 0.63 |
Mode of delivery | NVD C.S | 17 (68%) 8 (32%) | 12 (80%) 3 (20%) | 0.54 | 7 (28%) 18 (72%) | 3 (20%) 12 (80%) | 0.66 |
Maternal risk factors | Yes No | 13 (52%) 12 (48%) | 3 (20%) 12 (80%) | 0.04 | 14 (56%) 11 (44%) | 13 (86.6%) 2 (13.4%) | 0.04 |
Item | Patients (n = 50) | Controls (n = 30) | p-Value |
---|---|---|---|
Hb (gm/dL) | 12.9 ± 3.4 | 15.4 ± 2.2 | 0.04 |
WBCs (×10³/µL) | 20,038 ± 18,237.4 | 10,304 ± 3201.6 | 0.003 |
Platelets (×10³/µL) | 89 ± 8.4 | 255 ± 5.9 | 0.002 |
Neutrophils(×10³/µL) | 63.2 ± 12.9 | 37.5 ± 7.7 | 0.001 |
Staff (×10³/µL) | 11.8 ± 7.4 | 3.0 ± 1.2 | 0.004 |
Segmented(×10³/µL) | 51.9 ± 11.9 | 34.4 ± 7.5 | 0.01 |
ANC | 11,184.5 ± 75.7 | 3847.2 ± 13.7 | 0.001 |
I/T ratio | 0.2 ± 0.1 | 0.1 ± 0.03 | 0.01 |
CRP (mg/L) | 37.6 ± 9.02 | 6.0 ± 1.05 | 0.001 |
IL-6 (pg/mL) | 139.9 ± 70.19 | 5.8 ± 3.8 | 0.001 |
Neonatal. 25-OH Vit.D (nmol/L) | 6.4 ± 1.8 | 24.6 ± 2.2 | 0.001 |
Maternal. 25-OH Vit.D (nmol/L) | 42.5 ± 20.7 | 50.4 ± 21.4 | 0.01 |
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Gamal, T.S.; Madiha, A.-A.S.; Hanan, M.K.; Abdel-Azeem, M.E.-M.; Marian, G.S. Neonatal and Maternal 25-OH Vitamin D Serum Levels in Neonates with Early-Onset Sepsis. Children 2017, 4, 37. https://doi.org/10.3390/children4050037
Gamal TS, Madiha A-AS, Hanan MK, Abdel-Azeem ME-M, Marian GS. Neonatal and Maternal 25-OH Vitamin D Serum Levels in Neonates with Early-Onset Sepsis. Children. 2017; 4(5):37. https://doi.org/10.3390/children4050037
Chicago/Turabian StyleGamal, Taha Soliman, Abd-Allah Sayed Madiha, Mostafa Kamel Hanan, Mohamed El-Mazary Abdel-Azeem, and Gamil S. Marian. 2017. "Neonatal and Maternal 25-OH Vitamin D Serum Levels in Neonates with Early-Onset Sepsis" Children 4, no. 5: 37. https://doi.org/10.3390/children4050037