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Volume 8
Issue 3
10.3390/children8030212
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Review
Peer-Review Record

An Integrative Review Exploring Psycho-Social Impacts and Therapeutic Interventions for Parent Caregivers of Young People Living with Duchenne’s Muscular Dystrophy

Children 2021, 8(3), 212; https://doi.org/10.3390/children8030212
by Debra Porteous *, Barbara Davies *, Christine English * and Joanne Atkinson *
Reviewer 1: Anonymous
Reviewer 2:
Tai-Heng Chen
Children 2021, 8(3), 212; https://doi.org/10.3390/children8030212
Submission received: 31 January 2021 / Revised: 26 February 2021 / Accepted: 5 March 2021 / Published: 11 March 2021
(This article belongs to the Special Issue Psychosocial Interventions for Children and Adolescents with Chronic or Long-Term Health Conditions)

Round 1

Reviewer 1 Report

The review  describes about the psycho-social impact of parents of the DMD patients. The review is well written and the method is sound in terms of keywords used for search strategy. However, it needs significant improvement in describing the main findings. I have some suggestions as descibed below

  1. The authors have already defined the research questions but the main findings are not presented accordingly. It can be presented in a better way.
  2. It will be helpful if the author will provide tables describing about the effect on father and mother separately.
  3. Thearpeutic interventions and accessibility of the psycho-social intervention should  be described separately in the main findings. 
  4. In the introduction, the author should give a brief introduction about DMD, BMD and Limb-girdle MD.
  5. The effect of DMD is different on parents as it progresses. The author should also describes about its effect on each parent. For example, what is the effect of DMD during childhood, adolescent and adulthood?

Author Response

Please see the attachment 

Author Response File: Author Response.docx

Reviewer 2 Report

Line 20: The term “life-limiting” for DMD is inappropriate.

Line 54: Since this paper focus on discussing Duchenne Muscular Dystrophy, I am wondering why authors used the keywords of muscular dystrophy, a broader scope of the selected field.

Main criticism: As indicated in the paper, the selection ranges from 2010 to 2020; however, during the past decade, the care method of muscular dystrophy, especially DMD, has been improved greatly. However, the authors just focused on the discussion of respiratory support (NIV) and nutritional issues. Besides, some novel therapies, such as ASO or gene therapy, are undergoing clinical trials. Of note, one approved drug, Translarna (Ataluren), has been applied to non-sense mutation DMD patients. However, the authors did not discuss the impact of these novel therapies on DMD. I suggest that the authors include several references regarding DMD therapies and discuss their psycho-social effects more specifically.

The authors should discuss the influencing factors of selecting palliative care, when and who makes the decision.

Author Response

Please see the attachment

Author Response File: Author Response.docx

Round 2

Reviewer 1 Report

The authors have addressed all my concerns and the quality of manuscript has improved significantly. 

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