Next Article in Journal
The Association between Stress and Children’s Weight Status: A School-Based, Epidemiological Study
Next Article in Special Issue
MicroRNA-126-3p/5p and Aortic Stiffness in Patients with Turner Syndrome
Previous Article in Journal
Unique Pulmonary Hypertension in Young Children: A Case Series Study
Previous Article in Special Issue
Cor Triatriatum Dexter: Contrast Echocardiography Is Key to the Diagnosis of a Rare but Treatable Cause of Neonatal Persistent Cyanosis
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Children
Volume 9
Issue 7
10.3390/children9071065
children-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Clinical Efficacy of Empirical Therapy in Children with Vasovagal Syncope

by
Chunyan Tao
1,2,†,
Yaxi Cui
1,†,
Chunyu Zhang
1,
Xueqin Liu
1,
Qingyou Zhang
1,
Ping Liu
1,
Yuli Wang
1,
Junbao Du
1,3 and
Hongfang Jin
1,*
1
Department of Pediatrics, Peking University First Hospital, Beijing 100034, China
2
Department of Genetics and Endocrinology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, China
3
Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Children 2022, 9(7), 1065; https://doi.org/10.3390/children9071065
Submission received: 1 July 2022 / Revised: 14 July 2022 / Accepted: 15 July 2022 / Published: 17 July 2022
(This article belongs to the Special Issue Research Progress of the Pediatric Cardiology)
Browse Figures
Versions Notes

Abstract

(1) Background: This case-control study was designed to assess the efficacy of empiric treatment for vasovagal syncope in children; (2) Methods: We retrospectively enrolled 181 children with vasovagal syncope from the Department of Pediatrics of Peking University First Hospital. The participants were categorized into four groups, based on the empiric treatment received: conventional treatment, including health education and orthostatic training; conventional treatment plus oral rehydration salts; conventional treatment plus metoprolol; conventional treatment plus midodrine hydrochloride. Patients were followed up to evaluate the syncopal or presyncopal recurrence. Kaplan–Meier curves were drawn to explore the syncopal or presyncopal recurrence in children, and the differences were compared among the groups using a log-rank test; (3) Results: Among the 181 children with vasovagal syncope, 11 were lost to follow-up. The median time of follow-up was 20 (8, 42) months. The Kaplan–Meier survival curve showed no significant difference in syncopal or presyncopal recurrence in children treated with different empiric options according to a log-rank test (χ2 = 1.328, p = 0.723); (4) Conclusions: The efficacy of unselected empiric therapy of vasovagal syncope in children was limited, and the individualized therapies merit further studies.
Keywords: children; efficacy; empiric therapy; vasovagal syncope children; efficacy; empiric therapy; vasovagal syncope

Share and Cite

MDPI and ACS Style

Tao, C.; Cui, Y.; Zhang, C.; Liu, X.; Zhang, Q.; Liu, P.; Wang, Y.; Du, J.; Jin, H. Clinical Efficacy of Empirical Therapy in Children with Vasovagal Syncope. Children 2022, 9, 1065. https://doi.org/10.3390/children9071065

AMA Style

Tao C, Cui Y, Zhang C, Liu X, Zhang Q, Liu P, Wang Y, Du J, Jin H. Clinical Efficacy of Empirical Therapy in Children with Vasovagal Syncope. Children. 2022; 9(7):1065. https://doi.org/10.3390/children9071065

Chicago/Turabian Style

Tao, Chunyan, Yaxi Cui, Chunyu Zhang, Xueqin Liu, Qingyou Zhang, Ping Liu, Yuli Wang, Junbao Du, and Hongfang Jin. 2022. "Clinical Efficacy of Empirical Therapy in Children with Vasovagal Syncope" Children 9, no. 7: 1065. https://doi.org/10.3390/children9071065

APA Style

Tao, C., Cui, Y., Zhang, C., Liu, X., Zhang, Q., Liu, P., Wang, Y., Du, J., & Jin, H. (2022). Clinical Efficacy of Empirical Therapy in Children with Vasovagal Syncope. Children, 9(7), 1065. https://doi.org/10.3390/children9071065

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop