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Endocrines
Volume 4
Issue 2
10.3390/endocrines4020022
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Review

Insights into Androgen Receptor Action in Lung Cancer

by
Darko Durovski
1,
Milica Jankovic
2 and
Stefan Prekovic
3,*
1
Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
2
Department of Molecular Biology and Endocrinology, “Vinča” Institute of Nuclear Sciences, University of Belgrade, 11000 Belgrade, Serbia
3
Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
*
Author to whom correspondence should be addressed.
Endocrines 2023, 4(2), 269-280; https://doi.org/10.3390/endocrines4020022
Submission received: 10 January 2023 / Revised: 28 February 2023 / Accepted: 28 March 2023 / Published: 3 April 2023
(This article belongs to the Section Endocrine Oncology)
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Abstract

Sex hormones and their receptors play a crucial role in human sexual dimorphism and have been traditionally associated with hormone-dependent cancers like breast, prostate, and endometrial cancer. However, recent research has broadened our understanding by revealing connections with other types of cancers, such as lung cancer, where the androgen receptor has been found to be particularly significant. This review aims to explore the molecular mechanisms of androgen action in lung cancer pathogenesis and progression, highlighting the potential of inhibiting the androgen receptor signaling pathway as a therapeutic strategy for lung cancer treatment.
Keywords: androgens; nuclear receptors; lung cancer androgens; nuclear receptors; lung cancer

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MDPI and ACS Style

Durovski, D.; Jankovic, M.; Prekovic, S. Insights into Androgen Receptor Action in Lung Cancer. Endocrines 2023, 4, 269-280. https://doi.org/10.3390/endocrines4020022

AMA Style

Durovski D, Jankovic M, Prekovic S. Insights into Androgen Receptor Action in Lung Cancer. Endocrines. 2023; 4(2):269-280. https://doi.org/10.3390/endocrines4020022

Chicago/Turabian Style

Durovski, Darko, Milica Jankovic, and Stefan Prekovic. 2023. "Insights into Androgen Receptor Action in Lung Cancer" Endocrines 4, no. 2: 269-280. https://doi.org/10.3390/endocrines4020022

APA Style

Durovski, D., Jankovic, M., & Prekovic, S. (2023). Insights into Androgen Receptor Action in Lung Cancer. Endocrines, 4(2), 269-280. https://doi.org/10.3390/endocrines4020022

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