Isolated Dissection of the Ductus Arteriosus Associated with Sudden Unexpected Intrauterine Death
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Study Limitation
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Case | Sex | GA | Ethnicity | Risk Factors of Mother | Pregnancy | Medications during Pregnancy | Reported Symptoms during Pregnancy |
---|---|---|---|---|---|---|---|
1 | M | 33 | Caucasian | Smoking during pregnancy | First | None | None |
2 | M | 32 | Caucasian | No risk factors | Second | None | None |
3 | M | 32 | Caucasian | Hypertension, smoking during pregnancy | First | None | Hypertension |
4 | M | 26 | Caucasian | No risk factors | First | None | None |
5 | M | 33 | Caucasian | Pre-eclampsia | First | None | Hypertension |
Case | Body Weight | Heart Weight | Wall Thickness RV/S/LV mm | GM | DA Anatomical Macroscopic Description | Foramen Ovale |
---|---|---|---|---|---|---|
1 | 1750 g | 8.7 g | 2.5/2.8/2.8 | III | Dissecting DA | Restrictive |
2 | 1650 g | 8.5 g | 2.4/2.5/2.5 | III | Dissecting DA | Patent |
3 | 1300 g | 7 g | 2/2/2.2 | III | Dissecting DA | Patent |
4 | 810 g | 5 g | 1.2/1.3/1.8 | III | Dissecting DA | Patent |
5 | 1670 g | 9 g | 2.3/2.5/2.5 | I | Dissecting DA | Patent |
Case | Intimal Flap | Intima | Media-Adventitia | Inflammation | Apoptosis (TUNEL) |
---|---|---|---|---|---|
1 | Absent | No subendothelial cushions, thrombotic lumen occlusion | Outer dissecting hematoma, no cystic medial necrosis | Absent | + |
2 | Present | No subendothelial cushions | Outer dissecting hematoma, cystic medial necrosis | Absent | +++ |
3 | Present | Subendothelial cushions, thrombus stratification | Outer dissecting hematoma, cystic medial necrosis | Absent | + |
4 | Present | No subendothelial cushions | Outer dissecting hematoma, no cystic medial necrosis | Absent | +++ |
5 | Present | Subendothelial cushions | Dissecting hematoma, cystic medial necrosis | Absent | + |
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Fedrigo, M.; Visentin, S.; Veronese, P.; Barison, I.; Giarraputo, A.; Cosmi, E.; Thiene, G.; Gervasi, M.T.; Basso, C.; Angelini, A. Isolated Dissection of the Ductus Arteriosus Associated with Sudden Unexpected Intrauterine Death. J. Cardiovasc. Dev. Dis. 2021, 8, 91. https://doi.org/10.3390/jcdd8080091
Fedrigo M, Visentin S, Veronese P, Barison I, Giarraputo A, Cosmi E, Thiene G, Gervasi MT, Basso C, Angelini A. Isolated Dissection of the Ductus Arteriosus Associated with Sudden Unexpected Intrauterine Death. Journal of Cardiovascular Development and Disease. 2021; 8(8):91. https://doi.org/10.3390/jcdd8080091
Chicago/Turabian StyleFedrigo, Marny, Silvia Visentin, Paola Veronese, Ilaria Barison, Alessia Giarraputo, Erich Cosmi, Gaetano Thiene, Maria Teresa Gervasi, Cristina Basso, and Annalisa Angelini. 2021. "Isolated Dissection of the Ductus Arteriosus Associated with Sudden Unexpected Intrauterine Death" Journal of Cardiovascular Development and Disease 8, no. 8: 91. https://doi.org/10.3390/jcdd8080091