Highly Stretchable, Self-Healing, Injectable and pH Responsive Hydrogel from Multiple Hydrogen Bonding and Boron-Carbohydrate Interactions
Abstract
:1. Introduction
2. Results and Discussion
3. Conclusions
4. Materials and Methods
4.1. Materials
4.2. Poly(LAEMA-st-DMA) (PLD) Preparation
4.3. Hydrogel Fabrication and Characterization
4.4. Characterization
4.4.1. The 1H Nuclear Magnetic Resonance (NMR)
4.4.2. Gel Permeation Chromatography (GPC)
4.4.3. Rheometer
4.5. Responsiveness of Hydrogel
4.6. Cell Culture
4.7. Cytotoxicity of PLD
4.8. The 3D Live/Dead Assay
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Hydrogel | 10 wt% PLD (mL) | 10 wt% Borax (μL) |
---|---|---|
LB 41 | 0.3 | 2.63 |
LB 21 | 0.3 | 5.25 |
LB 11 | 0.3 | 10.5 |
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Peng, Y.-Y.; Cheng, Q.; Wu, M.; Wang, W.; Zhao, J.; Diaz-Dussan, D.; McKay, M.; Zeng, H.; Ummartyotin, S.; Narain, R. Highly Stretchable, Self-Healing, Injectable and pH Responsive Hydrogel from Multiple Hydrogen Bonding and Boron-Carbohydrate Interactions. Gels 2023, 9, 709. https://doi.org/10.3390/gels9090709
Peng Y-Y, Cheng Q, Wu M, Wang W, Zhao J, Diaz-Dussan D, McKay M, Zeng H, Ummartyotin S, Narain R. Highly Stretchable, Self-Healing, Injectable and pH Responsive Hydrogel from Multiple Hydrogen Bonding and Boron-Carbohydrate Interactions. Gels. 2023; 9(9):709. https://doi.org/10.3390/gels9090709
Chicago/Turabian StylePeng, Yi-Yang, Qiuli Cheng, Meng Wu, Wenda Wang, Jianyang Zhao, Diana Diaz-Dussan, Michelle McKay, Hongbo Zeng, Sarute Ummartyotin, and Ravin Narain. 2023. "Highly Stretchable, Self-Healing, Injectable and pH Responsive Hydrogel from Multiple Hydrogen Bonding and Boron-Carbohydrate Interactions" Gels 9, no. 9: 709. https://doi.org/10.3390/gels9090709