4. Discussion
Our data indicate that the MMHU has, for the last ten years, served successfully the mental health needs of a large group of patients living in rural and semi-rural areas of the Heraklion prefecture, with about 110,000 residents not having access to mental health care [
5]. The unit has evaluated about 3,400 patients, and more than half of them suffer from depressive or anxiety disorder. Our data are consistent with data from the MMHUs in other areas in Greece, where patients with affective disorders represented the majority of those seeking the MMHU services [
11,
12]. About one fifth of the entire group of patients has a diagnosis of a severe psychiatric disorder, such as psychosis or bipolar disorder, which is somewhat lower than the number of patients with severe psychiatric disorders followed by a MMHU in northern Greece (Alexandroupolis) [
12]. Based on preliminary data presented in national conferences but unpublished yet, there is a reduction in the relapses and readmissions in the in-patient psychiatric unit of the university hospital of patients with psychosis or bipolar disorder [
13,
14], which is in line with previous research in Greece and abroad [
15,
16]. This single index indicates that the impact of the MMHU on mental health needs of this population is successful. However, our impression is that the demands for mental health services are only partially met by the current structure and function of the unit.
Our data highlight some interesting issues that deserve to be discussed. The first is that only a relatively small portion of patients with severe psychiatric disorders is followed by the MMHU. If we assume, based on the published literature that a conservative prevalence of these disorders is 1% [
17,
18,
19,
20], then we should expect that in this catchment area there are about 1,100 patients with psychosis and another 1,100 with bipolar disorder. We follow only about 450 patients with psychosis and another 150 with bipolar disorder. This raises important questions: are these patients with severe psychiatric disorders followed by other mental health facilities or other practitioners, so that the illness remains “secret” from the rest of their small community? Are these patients living within the community supported/protected by their family, functioning at a low level both socially and personally and without any systematic follow-up of their mental health problem? Furthermore, our data indicate that the mean age of the first contact of patients with severe mental illness with the MMHU is relatively old, about 45 years old. This is consistent with findings from the university hospital that the mean age of the first admission for patients with severe mental illness is about 42 years old [
21]. This is significantly older than the mean age of first admission (about 27 years) based on international bibliography [
22,
23,
24,
25] and unpublished data from the Department of Psychiatry of the University of Athens. Our data on the onset of psychotic symptoms between 28–31 years old are similar to the international literature. For example, the age of the first psychotic episode is reported to range between 22 and 28 years old [
24,
26]. Our findings are also consistent with results from other parts of Greece (Ioannina) that have shown similar age range of the first episode of psychosis [
27]. Further, it has been reported that onset of psychotic symptomatology was three to four years earlier for men compared to women [
24]. Similarly, the age of onset of bipolar disorder was found to be at the middle-to late twenties (23–28 years) [
28,
29]. Finally, a recent meta-analysis showed that there is a 5.9-year duration of untreated bipolar disorder and a 3.5-year delay in help-seeking [
30].
These findings of our study support the hypothesis that the Cretan families try to take care of their ill patients within the family and outside of the public mental health system [
31,
32]. This can be related to an effort to avoid the stigma associated with severe mental illness [
33] or mistrust of the public health system. Research data are needed to support these alternative hypotheses.
The late contact of patients with severe mental illness with our unit indicates that a large number of younger patients are outside of the radar of the MMHU or of Community Services, such as PCHC, Municipal Social Services, Program “Help at Home” etc. It is well established that early detection and intervention in patients with severe mental illness is associated with better outcome [
34]. It is one of our biggest challenges to increase the number of young patients with severe mental illness that are followed by our unit. There is no ready recipe for how this can be achieved. It is our impression and our goal to educate in a more systematic way the health workers of the “first line” health services, such as primary care physicians, municipal social workers, visiting nurses, etc., to early detect and refer these patients to the MMHU. Additionally, we have to have an open sincere dialogue with our colleagues in private practice if a visit here and there by a person with severe mental illness with limited or no insight to their problem and a family that desperately tries to keep the problem “secret” from the community, serves the purpose of continuity of care, a primary goal in keeping these patients safe and healthy in their communities. Finally, we have to explore the potential helpful role of key individuals in these communities, such as priests, teachers, local community authorities, police, members of volunteer groups such as Red Cross, etc.
Another interesting finding of our data is the large number of patients with a diagnosis of depression or anxiety disorder, the relatively high proportion of women compared to men as well as the fact that they are predominantly older. These findings have several implications. First, depression and anxiety are very common in rural areas of Crete [
35], similar to epidemiologic data from urban populations [
36,
37,
38]. The large majority of these patients were referred by their primary care physicians and most ended up receiving medication. Although our initial goal was to focus on patients with severe psychiatric disorders, we could not deny our services to these patients with depression or anxiety disorder associated with significant subjective dysphoria and/or daily dysfunction and/or multiple physical complains, not explained by organic causes. It is our impression based on our current structure and capacity that we cannot follow up systematically with this large group of patients, including regular medication check-ups. In our view, there is a need to train primary care physicians to be able to handle this large group, including, but not only, medication management. Second, a large percentage of these patients are women who are old and living alone, which is in line with previous findings [
11,
12,
39]. Existing literature supports that depression and anxiety are more prevalent in women with a ratio 2:1, whereas there are no significant differences in terms of age distribution [
40]. The higher proportion of older women in our sample may be related to the fact that older women feel more comfortable visiting a health professional compared to older men. The low percentage of young individuals in our depressed/anxiety-diagnosed population may be related to the fact that most young people have left rural areas for better professional educational and life opportunities in urban areas. An alternative, not mutually exclusive, explanation is that young people facing emotional problems may seek help far from their small communities to secure “anonymity”. The finding that one third of depressed individuals live alone defeats the common assumption that in small communities in rural areas in Greece there is close connectivity between its members. Professor Lyberaki has demonstrated that older women living in rural areas in Greece are lonelier than their counterparts living in European countries, such as Sweden or Germany [
41]. Since our data show that depression and anxiety in this group of patients are related to a significant degree to lack of family and social support and corresponding loneliness, there is a need of community structures to assist with the socialization and community involvement of these patients. Church, cultural organizations and volunteering groups have to fill in the gaps created by the socioeconomic and family structure changes that took place in our country over the last 4–5 decades. A positive finding of our data is that older people, although of less education compared to the younger ones, have overcome the stigma of the mental illness, and do not have a problem visiting a mental health care professional in their hometown. It appears that the stigma is stronger in younger individuals with severe mental illness and their families because of the fear that, if the community “knows”, this will have an adverse impact on their professional, personal and family lives.
Our descriptive study has several strengths, such as its large sample size, its wide age spectrum, the inclusion of both genders and its long-term existence under stable academic and medical leadership. However, several limitations should be noted. One limitation of our study is that the diagnoses were provided by multiple physicians. However, all these physicians were board-certified psychiatrists using a semi-structured interview and followed the criteria of a single diagnostic system, ICD-10. Another limitation is that, in some of our analyses, we have missing data for key variables such as age, gender, education and socioeconomic status. However, there were no statistical differences between the subgroup and the entire group of subjects in terms of key variables such as age, gender, education and socioeconomic status. Finally, our study is cross-sectional and does not allow for any etiologic associations.
5. Conclusions
In conclusion, our preliminary data indicate that the MMHU is a model that, if adequately supported, can serve the increasing mental health needs of people living in rural areas. The accomplishment of such a goal requires strong connection with health and social services and key institutions in these communities. Second, a large number of individuals with severe mental illnesses, such as psychosis or bipolar disorder, are not being followed by the MMHU. One of the future challenges is to explore and apply novel tactics in early detection and intervention for these individuals. Third, adequate care of older patients with anxiety and depression cannot be accomplished without the active involvement of the primary care physicians and other health professionals such as “Help at Home”. Lastly, the loneliness and the socialization of these patients, particularly of women, cannot be dealt with just by medication. The potential usefulness of mental health units, such as day care centers, has to be examined. However, that these people live in remote small communities without transportation raises a question of how realistic and effective such an approach can be, currently. In the meantime, the active role of institutions such as churches, cultural organizations, and volunteer groups may be particularly useful, albeit not taken for granted.