The Association of High Burden Premature Ventricular Contractions with Esophageal/Upper GI Diseases
Abstract
:1. Introduction
2. Physiologic Mechanisms of PVCs
3. Cardio-Physiologic Consequences of PVCs
4. Clinical Features and Therapies
5. Genetic Associations
6. Methods
6.1. Clinical Subject Selection
6.2. Statistics
6.3. EKG Analysis
7. Case Descriptions
7.1. Subject 1—Index Case
7.2. Subject 2
7.3. Subject 3
7.4. Subject 4
7.5. Subject 5
7.6. Subject 6
8. Discussion
9. Limitations
10. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
References
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Age | Sex | GI Pathology | Esophageal Intervention | Baseline PVCs (%) | Post Intervention PVCs (%) | % Decline | p-Value |
---|---|---|---|---|---|---|---|
60 | F | Hiatal hernia | LINX repair | 26.00 | <0.01 | 99.96 | |
46 | F | Achalasia | Esophageal dilation | 17.00 | <1.0 | 94.11 | |
62 | F | Lap-band | Lap-band removal | 20.00 | 10.70 | 46.50 | |
74 | M | Esophageal stenosis | Esophageal dilation | 12.29 | 7.70 | 37.34 | |
67 | F | Hiatal hernia | Hernia repair | 12.4 | 2.6 | 79.03 | |
69 | M | Esophageal stenosis | Esophageal dilation | 23.7 | 11.0 | 53.5 | |
68.34% | 0.024 |
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Khimani, F.; Kulkarni, C.; Haase, E.; Moore, P.; Murdock, P.; Ramanathan, A.; Wolf, A.; Sathyamoorthy, M. The Association of High Burden Premature Ventricular Contractions with Esophageal/Upper GI Diseases. Hearts 2024, 5, 516-528. https://doi.org/10.3390/hearts5040038
Khimani F, Kulkarni C, Haase E, Moore P, Murdock P, Ramanathan A, Wolf A, Sathyamoorthy M. The Association of High Burden Premature Ventricular Contractions with Esophageal/Upper GI Diseases. Hearts. 2024; 5(4):516-528. https://doi.org/10.3390/hearts5040038
Chicago/Turabian StyleKhimani, Faria, Chandana Kulkarni, Erin Haase, Peyton Moore, Paul Murdock, Akash Ramanathan, Adam Wolf, and Mohanakrishnan Sathyamoorthy. 2024. "The Association of High Burden Premature Ventricular Contractions with Esophageal/Upper GI Diseases" Hearts 5, no. 4: 516-528. https://doi.org/10.3390/hearts5040038