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Review

A Review of Cardiovascular Risk Factors in Women with Psychosis

by
Alexandre González-Rodríguez
1,2,*,
Mary V. Seeman
3,
Armand Guàrdia
1,
Mentxu Natividad
1,
Eloïsa Román
1,
Eduard Izquierdo
1 and
José A. Monreal
1,2,4
1
Department of Mental Health, Mutua Terrassa University Hospital, Teaching and Research Foundation Mutua Terrassa, Department of Psychiatry, University of Barcelona, 5 Dr Robert Square, 08221 Terrassa, Spain
2
CIBERSAM, 08221 Terrassa, Spain
3
Department of Psychiatry, University of Toronto, #605, 260 Heath Street West, Toronto, ON M5T 1R8, Canada
4
Institut de Neurociències, UAB, 08221 Terrassa, Spain
*
Author to whom correspondence should be addressed.
Women 2023, 3(2), 200-213; https://doi.org/10.3390/women3020016
Submission received: 23 November 2022 / Revised: 28 March 2023 / Accepted: 29 March 2023 / Published: 10 April 2023
(This article belongs to the Special Issue Psychosis in Women)
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Abstract

The presence of medical comorbidities in women with psychotic disorders can lead to poor medical and psychiatric outcomes. Of all comorbidities, cardiovascular disease is the most frequent, and the one most likely to cause early death. We set out to review the evidence for cardiovascular risk factors (CRFs) in women with schizophrenia-related disorders and for interventions commonly used to reduce CRFs. Electronic searches were conducted on PubMed and Scopus databases (2017–2022) to identify papers relevant to our aims. A total of 17 studies fulfilled our inclusion criteria. We found that CRFs were prevalent in psychotic disorders, the majority attributable to patient lifestyle behaviors. We found some inconsistencies across studies with regard to gender differences in metabolic disturbances in first episode psychosis, but general agreement that CRFs increase at the time of menopause in women with psychotic disorders. Primary care services emerge as the best settings in which to detect CRFs and plan successive intervention strategies as women age. Negative symptoms (apathy, avolition, social withdrawal) need to be targeted and smoking cessation, a heart-healthy diet, physical activity, and regular sleep routines need to be actively promoted. The goal of healthier hearts for women with psychotic disorders may be difficult, but it is achievable.
Keywords: schizophrenia; psychosis; comorbidity; risk intervention; menopause; aging schizophrenia; psychosis; comorbidity; risk intervention; menopause; aging

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MDPI and ACS Style

González-Rodríguez, A.; Seeman, M.V.; Guàrdia, A.; Natividad, M.; Román, E.; Izquierdo, E.; Monreal, J.A. A Review of Cardiovascular Risk Factors in Women with Psychosis. Women 2023, 3, 200-213. https://doi.org/10.3390/women3020016

AMA Style

González-Rodríguez A, Seeman MV, Guàrdia A, Natividad M, Román E, Izquierdo E, Monreal JA. A Review of Cardiovascular Risk Factors in Women with Psychosis. Women. 2023; 3(2):200-213. https://doi.org/10.3390/women3020016

Chicago/Turabian Style

González-Rodríguez, Alexandre, Mary V. Seeman, Armand Guàrdia, Mentxu Natividad, Eloïsa Román, Eduard Izquierdo, and José A. Monreal. 2023. "A Review of Cardiovascular Risk Factors in Women with Psychosis" Women 3, no. 2: 200-213. https://doi.org/10.3390/women3020016

APA Style

González-Rodríguez, A., Seeman, M. V., Guàrdia, A., Natividad, M., Román, E., Izquierdo, E., & Monreal, J. A. (2023). A Review of Cardiovascular Risk Factors in Women with Psychosis. Women, 3(2), 200-213. https://doi.org/10.3390/women3020016

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