An Unusual Cause of Acute Kidney Injury in Pregnancy: Beware of HELLP Look-Alikes
Abstract
:1. Background
2. The Case
3. Discussion
Author Contributions
Funding
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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At Referral | Puerperium | 3 Weeks after Delivery, Kidney Biopsy | 8 Weeks after Delivery | |
---|---|---|---|---|
S Cr (mg/dL) | 3.3 | 6.3 | 3.3 | 0.9 |
BUN (mg/dL) | 30.8 | 54.7 | 67.8 | 12.1 |
e-GFR (mL/min) | - | - | 19 | 89 |
Albumin (g/dL) | 4.55 | 4.1 | 3.7 | 4 |
Total proteins | 7.5 | 7.2 | 7 | 7.3 |
Proteinuria (g/24 h) | - | - | 11.39 | 0.486 |
Haemoglobin (g/dL) | 14.6 | 11.2 | 11.4 | 12.9 |
Platelets (mm3) | 48,000 | 142 | 397 | 396 |
LDH (UI/L) | 978 | 432 | 242 | 260 |
AST (UI/L) | 750 | 363 | 46 | 25 |
ALT (UI/L) | 1265 | 273 | 51 | 43 |
Total bilirubin(mg/dL) | 3.2 | 0.6 | 0.3 | 0.4 |
Potassium (mEq/L) | 4.7 | 5.7 | 4.2 | 4 |
HCO3 (mEq/L) | 14 | 10.4 | 19.2 | 25 |
Immunologic markers: C3 96.5 mg/dL (90–180 mg/dL), C4 12.20 mg/dL (10–40 mg/dL), ANA negative B2 glycoprotein (IgG) 3.9 CU, b2 Glycoprotein (IgM) 1.4 CU, anticardiolipin (IgM) 1.4 CU, anti-SM antibodies >3.3 CU, DNA double-strain antibodies >9.8 UI/ml | ||||
Thrombotic microangiopathic screening: IgG antibodies ADAMS-13(J) 1.83 U/mL negative (negative <12); positive >15 Adams-13 activity (j) 0.75 (0.4–1.3 U/mL) Adams-13 activity 75% (40–130%) Haptoglobin 27.1 (30–200 mg/dL) | ||||
Viral markers: Hepatitis B, C, HIV negative |
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Orozco-Guillen, O.A.; Soto-Abram, V.; Moguel-Gonzalez, B.; Madero, M.; Piccoli, G.B. An Unusual Cause of Acute Kidney Injury in Pregnancy: Beware of HELLP Look-Alikes. Kidney Dial. 2022, 2, 588-594. https://doi.org/10.3390/kidneydial2040053
Orozco-Guillen OA, Soto-Abram V, Moguel-Gonzalez B, Madero M, Piccoli GB. An Unusual Cause of Acute Kidney Injury in Pregnancy: Beware of HELLP Look-Alikes. Kidney and Dialysis. 2022; 2(4):588-594. https://doi.org/10.3390/kidneydial2040053
Chicago/Turabian StyleOrozco-Guillen, Oralia Alejandra, Virgilia Soto-Abram, Bernardo Moguel-Gonzalez, Magdalena Madero, and Giorgina Barbara Piccoli. 2022. "An Unusual Cause of Acute Kidney Injury in Pregnancy: Beware of HELLP Look-Alikes" Kidney and Dialysis 2, no. 4: 588-594. https://doi.org/10.3390/kidneydial2040053