Diabetes, also known as diabetes mellitus, occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin that it produces. In 2019, about 8.8% of the worldwide adult population had diabetes. Considering how widespread the disease is, we would like to take this opportunity to extend our appreciation to all of the researchers who have contributed to the fight against this disease. In particular, we would like to highlight multiple research projects in this field, which cover the disease’s pathogenesis, clinical manifestation, early detection, and new therapeutic strategies, as well as the pandemic's prevalence and incidence.

The list of relevant papers can be seen below:

“The Effects of Metformin on the Gut Microbiota of Patients with Type 2 Diabetes: A Two-Center, Quasi-Experimental Study”
by Nakajima, H.; Takewaki, F.; Hashimoto, Y.; Kajiyama, S.; Majima, S.; Okada, H.; Senmaru, T.; Ushigome, E.; Nakanishi, N.; Hamaguchi, M.; Yamazaki, M.; Tanaka, Y.; Oikawa, Y.; Nakajima, S; Ohno, H. and Fukui, M.
Life 2020, 10(9), 195; https://doi.org/10.3390/life10090195
Available online: https://www.mdpi.com/2075-1729/10/9/195

“Mitochondrial Dysfunction in Pancreatic Alpha and Beta Cells Associated with Type 2 Diabetes Mellitus”
by Grubelnik, V.; Zmazek, J.; Markovič, R.; Gosak, M. and Marhl, M.
Life 2020, 10(12), 348; https://doi.org/10.3390/life10120348
Available online: https://www.mdpi.com/2075-1729/10/12/348

“Loganic Acid, an Iridoid Glycoside Extracted from Cornus mas L. Fruits, Reduces of Carbonyl/Oxidative Stress Biomarkers in Plasma and Restores Antioxidant Balance in Leukocytes of Rats with Streptozotocin-Induced Diabetes Mellitus”
by Dzydzan, O.; Brodyak, I.; Sokół-Łętowska, A.; Kucharska, A. Z. and Sybirna, N.
Life 2020, 10(12), 349; https://doi.org/10.3390/life10120349
Available online: https://www.mdpi.com/2075-1729/10/12/349

“Improvement of Platelet Respiration by Cell–Permeable Succinate in Diabetic Patients Treated with Statins”
by Avram, V. F.; Bîna, A. M.; Sima, A.; Aburel, O. M.; Sturza, A.; Burlacu, O.; Timar, R. Z.; Muntean, D. M.; Elmér, E. and Crețu, O. M.
Life 2021, 11(4), 288; https://doi.org/10.3390/life11040288
Available online: https://www.mdpi.com/2075-1729/11/4/288

“Red Blood Cell Distribution Width Is Associated with Deterioration of Renal Function and Cardiovascular Morbidity and Mortality in Patients with Diabetic Kidney Disease”
by Roumeliotis, S.; Stamou, A.; Roumeliotis, A.; Theodoridis, M.; Leivaditis, K.; Panagoutsos, S. and Liakopoulos, V.
Life 2020, 10(11), 301; https://doi.org/10.3390/life10110301
Available online: https://www.mdpi.com/2075-1729/10/11/301

“Factors Affecting a Short-Term Response to Anti-VEGF Therapy in Diabetic Macular Edema”
by Usui-Ouchi, A.; Tamaki, A.; Sakanishi, Y.; Tamaki, K.; Mashimo, K.; Sakuma, T. and Ebihara, N.
Life 2021, 11(2), 83. https://doi.org/10.3390/life11020083
Available online: https://www.mdpi.com/2075-1729/11/2/83

“Association of Metabolically Healthy and Unhealthy Obesity Phenotype with Markers Related to Obesity, Diabetes among Young, Healthy Adult Men. Analysis of MAGNETIC Study”
by Lejawa, M.; Osadnik, K.; Czuba, Z.; Osadnik, T. and Pawlas, N.
Life 2021, 11(12), 1350; https://doi.org/10.3390/life11121350
Available online: https://www.mdpi.com/2075-1729/11/12/1350

“The Association of 3-Hydroxy-3-Methylglutaryl-CoA Reductase, Apolipoprotein E, and Solute Carrier Organic Anion Genetic Variants with Atorvastatin Response among Jordanian Patients with Type 2 Diabetes”
by Alhawari, H.; Jarrar, Y.; AlKhatib, M. A.; Alhawari, H.; Momani, M.; Zayed, A.; Alkamhawi, R. and Zihlif, M.
Life 2020, 10(10), 232; https://doi.org/10.3390/life10100232
Available online: https://www.mdpi.com/2075-1729/10/10/232

“Peripheral Neuropathy Presents Similar Symptoms and Pathological Changes in Both High-Fat Diet and Pharmacologically Induced Pre- and Diabetic Mouse Models”
by Jaroslawska, J.; Korytko, A.; Zglejc-Waszak, K.; Antonowski, T.; Pomianowski, A. S.; Wasowicz, K.; Wojtkiewicz, J. and Juranek, J. K.
Life 2021, 11(11), 1267; https://doi.org/10.3390/life11111267
Available online: https://www.mdpi.com/2075-1729/11/11/1267

“Use of Anti-Diabetic Agents in Non-Diabetic Kidney Disease: From Bench to Bedside”
by Chung, S. and Kim, G.-H.
Life 2021, 11(5), 389; https://doi.org/10.3390/life11050389
Available online: https://www.mdpi.com/2075-1729/11/5/389