18 October 2022
Molecules | Top 10 Cited Papers in 2021 in the Section “Medicinal Chemistry”


1. "Antibody–Drug Conjugates—A Tutorial Review
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by Stephanie Baah, Mark Laws and Khondaker Miraz Rahman
Molecules 2021, 26(10), 2943; https://doi.org/10.3390/molecules26102943
Full text available online: https://www.mdpi.com/1420-3049/26/10/2943

2. “Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus”
by Olivier Terrier, Sébastien Dilly, Andrés Pizzorno, Dominika Chalupska, Jana Humpolickova, Evžen Bouřa, Francis Berenbaum, Stéphane Quideau, Bruno Lina, Bruno Fève, Frédéric Adnet, Michèle Sabbah, Manuel Rosa-Calatrava, Vincent Maréchal, Julien Henri and Anny Slama-Schwok
Molecules 2021, 26(9), 2593; https://doi.org/10.3390/molecules26092593
Full text available online: https://www.mdpi.com/1420-3049/26/9/2593

3. “From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones”
by Madalena M. M. Pinto, Andreia Palmeira, Carla Fernandes, Diana I. S. P. Resende, Emília Sousa, Honorina Cidade, Maria Elizabeth Tiritan, Marta Correia-da-Silva and Sara Cravo
Molecules 2021, 26(2), 431; https://doi.org/10.3390/molecules26020431
Full text available online: https://www.mdpi.com/1420-3049/26/2/431

4. “A Global Review on Short Peptides: Frontiers and Perspectives”
by Vasso Apostolopoulos, Joanna Bojarska, Tsun-Thai Chai, Sherif Elnagdy, Krzysztof Kaczmarek, John Matsoukas, Roger New, Keykavous Parang, Octavio Paredes Lopez, Hamideh Parhiz, Conrad O. Perera, Monica Pickholz, Milan Remko, Michele Saviano, Mariusz Skwarczynski, Yefeng Tang, Wojciech M. Wolf, Taku Yoshiya, Janusz Zabrocki, Piotr Zielenkiewicz, Maha AlKhazindar, Vanessa Barriga, Konstantinos Kelaidonis, Elham Mousavinezhad Sarasia and Istvan Toth
Molecules 2021, 26(2), 430; https://doi.org/10.3390/molecules26020430
Full text available online: https://www.mdpi.com/1420-3049/26/2/430

5. “Current Updates on Naturally Occurring Compounds Recognizing SARS-CoV-2 Druggable Targets”
by Isabella Romeo, Francesco Mesiti, Antonio Lupia and Stefano Alcaro
Molecules 2021, 26(3), 632; https://doi.org/10.3390/molecules26030632
Full text available online: https://www.mdpi.com/1420-3049/26/3/632

6. “Improved Dermal and Transdermal Delivery of Curcumin with SmartFilms and Nanocrystals”
by Ralph W. Eckert, Sabrina Wiemann and Cornelia M. Keck
Molecules 2021, 26(6), 1633; https://doi.org/10.3390/molecules26061633
Full text available online: https://www.mdpi.com/1420-3049/26/6/1633

7. “NLRP3 Inflammasome Inhibitors in Cardiovascular Diseases”
by Eleonora Mezzaroma, Antonio Abbate and Stefano Toldo
Molecules 2021, 26(4), 976; https://doi.org/10.3390/molecules26040976
Full text available online: https://www.mdpi.com/1420-3049/26/4/976

8. “In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications—A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B”
by Rosaria Ottanà, Paolo Paoli, Mario Cappiello, Trung Ngoc Nguyen, Ilenia Adornato, Antonella Del Corso, Massimo Genovese, Ilaria Nesi , Roberta Moschini, Alexandra Naß, Gerhard Wolber and Rosanna Maccari
Molecules 2021, 26(2), 330; https://doi.org/10.3390/molecules26020330
Full text available online: https://www.mdpi.com/1420-3049/26/2/330

9. “Recent Advances in the Synthesis of β-Carboline Alkaloids”
by Tímea Szabó, Balázs Volk and Mátyás Milen
Molecules 2021, 26(3), 663; https://doi.org/10.3390/molecules26030663
Full text available online: https://www.mdpi.com/1420-3049/26/3/663

10. “Drug Discovery of Nucleos(t)ide Antiviral Agents: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Birthday”
by Guangdi Li, Tingting Yue, Pan Zhang, Weijie Gu, Ling-Jie Gao and Li Tan
Molecules 2021, 26(4), 923; https://doi.org/10.3390/molecules26040923
Full text available online: https://www.mdpi.com/1420-3049/26/4/923

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