The Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an international, peer-reviewed, open access journal published semimonthly online by MDPI, where you have free and unlimited access to the full text of all of the published articles. The International Bone Research Association (IBRA), Italian Resuscitation Council (IRC), Spanish Society of Hematology and Hemotherapy (SEHH), Japan Association for Clinical Engineers (JACE), European Independent Foundation in Angiology/Vascular Medicine (VAS) and others are all affiliated with JCM, and their members receive a discount on article processing charges.

JCM covers all topics related to clinical and pre-clinical practices and is dedicated to publishing high-quality original research, reviews or perspectives on clinical practice. We invite you to read our most cited papers published in 2022 below:

1. "Female Sex Is a Risk Factor Associated with Long-Term Post-COVID Related-Symptoms but Not with COVID-19 Symptoms: The LONG-COVID-EXP-CM Multicenter Study"
by César Fernández-de-las-Peñas, José D. Martín-Guerrero, Óscar J. Pellicer-Valero, Esperanza Navarro-Pardo, Víctor Gómez-Mayordomo, María L. Cuadrado, José A. Arias-Navalón, Margarita Cigarán-Méndez, Valentín Hernández-Barrera and Lars Arendt-Nielsen
J. Clin. Med. 2022, 11(2), 413; https://doi.org/10.3390/jcm11020413
Available online: https://www.mdpi.com/2077-0383/11/2/413

2. "XR (Extended Reality: Virtual Reality, Augmented Reality, Mixed Reality) Technology in Spine Medicine: Status Quo and Quo Vadis"
by Tadatsugu Morimoto, Takaomi Kobayashi, Hirohito Hirata, Koji Otani, Maki Sugimoto, Masatsugu Tsukamoto, Tomohito Yoshihara, Masaya Ueno and Masaaki Mawatari
J. Clin. Med. 2022, 11(2), 470; https://doi.org/10.3390/jcm11020470
Available online: https://www.mdpi.com/2077-0383/11/2/470

3. "Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices"
by Oksana Volod, Connor M. Bunch, Nuha Zackariya, Ernest E. Moore, Hunter B. Moore, Hau C. Kwaan, Matthew D. Neal, Mahmoud D. Al-Fadhl, Shivani S. Patel, Grant Wiarda et al.
J. Clin. Med. 2022, 11(3), 860; https://doi.org/10.3390/jcm11030860
Available online: https://www.mdpi.com/2077-0383/11/3/860

4. "Prognostic Factors for Post-COVID-19 Syndrome: A Systematic Review and Meta-Analysis"
by Giuseppe Maglietta, Francesca Diodati, Matteo Puntoni, Silvia Lazzarelli, Barbara Marcomini, Laura Patrizi and Caterina Caminiti
J. Clin. Med. 2022, 11(6), 1541; https://doi.org/10.3390/jcm11061541
Available online: https://www.mdpi.com/2077-0383/11/6/1541

5. "Different Methods to Improve the Monitoring of Noninvasive Respiratory Support of Patients with Severe Pneumonia/ARDS Due to COVID-19: An Update"
by Paolo Pelosi, Roberto Tonelli, Chiara Torregiani, Elisa Baratella, Marco Confalonieri, Denise Battaglini, Alessandro Marchioni, Paola Confalonieri, Enrico Clini, Francesco Salton et al.
J. Clin. Med. 2022, 11(6), 1704; https://doi.org/10.3390/jcm11061704
Available online: https://www.mdpi.com/2077-0383/11/6/1704

6. "Serological Response to Three, Four and Five Doses of SARS-CoV-2 Vaccine in Kidney Transplant Recipients"
by Bilgin Osmanodja, Simon Ronicke, Klemens Budde, Annika Jens, Charlotte Hammett, Nadine Koch, Evelyn Seelow, Johannes Waiser, Bianca Zukunft, Friederike Bachmann et al.
J. Clin. Med. 2022, 11(9), 2565; https://doi.org/10.3390/jcm11092565
Available online: https://www.mdpi.com/2077-0383/11/9/2565

7. "Cytokine Profiles as Potential Prognostic and Therapeutic Markers in SARS-CoV-2-Induced ARDS"
by Francesco Salton, Paola Confalonieri, Giuseppina Campisciano, Rossella Cifaldi, Clara Rizzardi, Daniele Generali, Riccardo Pozzan, Stefano Tavano, Chiara Bozzi, Giulia Lapadula et al.
J. Clin. Med. 2022, 11(11), 2951; https://doi.org/10.3390/jcm11112951
Available online: https://www.mdpi.com/2077-0383/11/11/2951

8. "Efficacy of Oxybrasion in the Treatment of Acne Vulgaris: A Preliminary Report"
by Karolina Chilicka, Aleksandra M. Rogowska, Renata Szyguła, Monika Rusztowicz and Danuta Nowicka
J. Clin. Med. 2022, 11(13), 3824; https://doi.org/10.3390/jcm11133824
Available online: https://www.mdpi.com/2077-0383/11/13/3824

9. "Efficacy of Hydrogen Purification and Cosmetic Acids in the Treatment of Acne Vulgaris: A Preliminary Report"
by Karolina Chilicka, Monika Rusztowicz, Aleksandra M. Rogowska, Renata Szyguła, Binnaz Asanova and Danuta Nowicka
J. Clin. Med. 2022, 11(21), 6269; https://doi.org/10.3390/jcm11216269
Available online: https://www.mdpi.com/2077-0383/11/21/6269

10. "The Role of Innate and Adaptive Immune Cells in the Pathogenesis and Development of the Inflammatory Response in Ulcerative Colitis"
by Aleksandra Kałużna, Paweł Olczyk and Katarzyna Komosińska-Vassev
J. Clin. Med. 2022, 11(2), 400; https://doi.org/10.3390/jcm11020400
Available online: https://www.mdpi.com/2077-0383/11/2/400

11. "Long-Term Outcomes of Implants Placed in Maxillary Sinus Floor Augmentation with Porous Fluorohydroxyapatite (Algipore® FRIOS®) in Comparison with Anorganic Bovine Bone (Bio-Oss®) and Platelet Rich Plasma (PRP): A Retrospective Study"
by Biagio Rapone, Alessio Danilo Inchingolo, Stefano Trasarti, Elisabetta Ferrara, Erda Qorri, Antonio Mancini, Nicola Montemurro, Antonio Scarano, Angelo Michele Inchingolo, Gianna Dipalma et al.
J. Clin. Med. 2022, 11(9), 2491; https://doi.org/10.3390/jcm11092491
Available online: https://www.mdpi.com/2077-0383/11/9/2491

12. "Exercise Training in Post-COVID-19 Patients: The Need for a Multifactorial Protocol for a Multifactorial Pathophysiology"
by Gaia Cattadori, Silvia Di Marco, Massimo Baravelli, Anna Picozzi and Giuseppe Ambrosio
J. Clin. Med. 2022, 11(8), 2228; https://doi.org/10.3390/jcm11082228
Available online: https://www.mdpi.com/2077-0383/11/8/2228

13. "The Risk of Spontaneous Abortion Does Not Increase Following First Trimester mRNA COVID-19 Vaccination"
by Ioana Mihaela Citu, Cosmin Citu, Florin Gorun, Ioan Sas, Felix Bratosin, Andrei Motoc, Bogdan Burlea, Ovidiu Rosca, Daniel Malita and Oana Maria Gorun
J. Clin. Med. 2022, 11(6), 1698; https://doi.org/10.3390/jcm11061698
Available online: https://www.mdpi.com/2077-0383/11/6/1698

14. "Age, Sex and Previous Comorbidities as Risk Factors Not Associated with SARS-CoV-2 Infection for Long COVID-19: A Systematic Review and Meta-Analysis"
by Kin Israel Notarte, Maria Helena Santos de Oliveira, Princess Juneire Peligro, Jacqueline Veronica Velasco, Imee Macaranas, Abbygail Therese Ver, Flos Carmeli Pangilinan, Adriel Pastrana, Nathaniel Goldrich, David Kavteladze et al.
J. Clin. Med. 2022, 11(24), 7314; https://doi.org/10.3390/jcm11247314
Available online: https://www.mdpi.com/2077-0383/11/24/7314

15. "Post-COVID-19 Syndrome: Involvement and Interactions between Respiratory, Cardiovascular and Nervous Systems"
by Valeria Visco, Carolina Vitale, Antonella Rispoli, Carmine Izzo, Nicola Virtuoso, Germano Junior Ferruzzi, Mario Santopietro, Americo Melfi, Maria Rosaria Rusciano, Angelantonio Maglio et al.
J. Clin. Med. 2022, 11(3), 524; https://doi.org/10.3390/jcm11030524
Available online: https://www.mdpi.com/2077-0383/11/3/524

16. "The Predictive Role of NLR and PLR in Outcome and Patency of Lower Limb Revascularization in Patients with Femoropopliteal Disease"
by Eliza Russu, Adrian Vasile Mureșan, Emil Marian Arbănași, Réka Kaller, Ioan Hosu, Septimiu Voidăzan, Eliza Mihaela Arbănași and Cătălin Mircea Coșarcă
J. Clin. Med. 2022, 11(9), 2620; https://doi.org/10.3390/jcm11092620
Available online: https://www.mdpi.com/2077-0383/11/9/2620

17. "Neutrophil-to-Lymphocyte Ratio (NLR) Is a Promising Predictor of Mortality and Admission to Intensive Care Unit of COVID-19 Patients"
by Matteo Regolo, Mauro Vaccaro, Alessandra Sorce, Benedetta Stancanelli, Michele Colaci, Giuseppe Natoli, Mario Russo, Innocenza Alessandria, Massimo Motta, Nicola Santangelo et al.
J. Clin. Med. 2022, 11(8), 2235; https://doi.org/10.3390/jcm11082235
Available online: https://www.mdpi.com/2077-0383/11/8/2235