We are delighted to present the highly cited papers in Web of Science from 2021 and 2022, a curated list of high-quality articles from Biomedicines (ISSN: 2227-9059), as shown below.

“Current FDA-Approved Therapies for High-Grade Malignant Gliomas”
by Jacob P. Fisher and David C. Adamson
Biomedicines 2021, 9(3), 324; https://doi.org/10.3390/biomedicines9030324
Available online: https://www.mdpi.com/2227-9059/9/3/324
Cited by 85 | Viewed by 6038

“Intestinal Barrier and Permeability in Health, Obesity and NAFLD”
by Piero Portincasa, Leonilde Bonfrate, Mohamad Khalil, Maria De Angelis, Francesco Maria Calabrese, Mauro D’Amato, David Q. -H. Wang and Agostino Di Ciaula
Biomedicines 2022, 10(1), 83; https://doi.org/10.3390/biomedicines10010083
Available online: https://www.mdpi.com/2227-9059/10/1/83
Cited by 47 | Viewed by 8195

“The Cardiovascular System in Space: Focus on In Vivo and In Vitro Studies”
by Ronni Baran, Shannon Marchal, Sebastian Garcia Campos, Emil Rehnberg, Kevin Tabury, Bjorn Baselet, Markus Wehland, Daniela Grimm and Sarah Baatout
Biomedicines 2022, 10(1), 59; https://doi.org/10.3390/biomedicines10010059
Available online: https://www.mdpi.com/2227-9059/10/1/59
Cited by 23 | Viewed by 4192

“The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities”
by Kamari Weaver and Rachid Skouta
Biomedicines 2022, 10(4), 891; https://doi.org/10.3390/biomedicines10040891
Available online: https://www.mdpi.com/2227-9059/10/4/891
Cited by 19 | Viewed by 4037

“Advances in Nanomaterial-Mediated Photothermal Cancer Therapies: Toward Clinical Applications”
by Hwa Seung Han and Ki Young Choi
Biomedicines 2021, 9(3), 305; https://doi.org/10.3390/biomedicines9030305
Available online: https://www.mdpi.com/2227-9059/9/3/305
Cited by 115 | Viewed by 6659

“Natural Photosensitizers in Antimicrobial Photodynamic Therapy”
by Ece Polat and Kyungsu Kang
Biomedicines 2021, 9(6), 584; https://doi.org/10.3390/biomedicines9060584
Available online: https://www.mdpi.com/2227-9059/9/6/584
Cited by 55 | Viewed by 7951

“Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics”
by Dixit V Bhalani, Bhingaradiya Nutan, Avinash Kumar and Arvind K. Singh Chandel
Biomedicines 2022, 10(9), 2055; https://doi.org/10.3390/biomedicines10092055
Available online: https://www.mdpi.com/2227-9059/10/9/2055
Cited by 25 | Viewed by 6026

“Inflammatory Mechanisms Contributing to Endothelial Dysfunction”
by Panagiotis Theofilis, Marios Sagris, Evangelos Oikonomou, Alexios S. Antonopoulos, Gerasimos Siasos, Costas Tsioufis and Dimitris Tousoulis
Biomedicines 2021, 9(7), 781; https://doi.org/10.3390/biomedicines9070781
Available online: https://www.mdpi.com/2227-9059/9/7/781
Cited by 121 | Viewed by 8508

“Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway”
by Masaru Tanaka, Fanni Toth, Helga Polyak, Agnes Szabo, Yvette Mandi and Laszlo Vecsei
Biomedicines 2021, 9(7), 734; https://doi.org/10.3390/biomedicines9070734
Available online: https://www.mdpi.com/2227-9059/9/7/734
Cited by 111 | Viewed by 8414

“Neuroinflammation in Alzheimer’s Disease”
by Isaac G. Onyango, Gretsen V. Jauregui, Maria Carna, James P. Bennett and Gorazd B. Stokin
Biomedicines 2021, 9(5), 524; https://doi.org/10.3390/biomedicines9050524
Available online: https://www.mdpi.com/2227-9059/9/5/524
Cited by 72 | Viewed by 10519

“Cutaneous Squamous Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches”
by Luca Fania, Dario Didona, Francesca Romana Di Pietro, Sofia Verkhovskaia, Roberto Morese, Giovanni Paolino, Michele Donati, Francesca Ricci, Valeria Coco, Francesco Ricci et al.
Biomedicines 2021, 9(2), 171; https://doi.org/10.3390/biomedicines9020171
Available online: https://www.mdpi.com/2227-9059/9/2/171
Cited by 56 | Viewed by 8303

“Can Metformin Exert as an Active Drug on Endothelial Dysfunction in Diabetic Subjects?”
by Teresa Salvatore, Pia Clara Pafundi, Raffaele Galiero, Luca Rinaldi, Alfredo Caturano, Erica Vetrano, Concetta Aprea, Gaetana Albanese, Anna Di Martino, Carmen Ricozzi et al.
Biomedicines 2021, 9(1), 3; https://doi.org/10.3390/biomedicines9010003
Available online: https://www.mdpi.com/2227-9059/9/1/3
Cited by 55 | Viewed by 4202

“Dopamine in Health and Disease: Much More Than a Neurotransmitter”
by Rafael Franco, Irene Reyes-Resina and Gemma Navarro
Biomedicines 2021, 9(2), 109; https://doi.org/10.3390/biomedicines9020109
Available online: https://www.mdpi.com/2227-9059/9/2/109
Cited by 47 | Viewed by 7569

“Memory Enhancement with Kynurenic Acid and Its Mechanisms in Neurotransmission”
by Diana Martos, Bernadett Tuka, Masaru Tanaka, Laszlo Vecsei and Gyula Telegdy
Biomedicines 2022, 10(4), 849; https://doi.org/10.3390/biomedicines10040849
Available online: https://www.mdpi.com/2227-9059/10/4/849
Cited by 42 | Viewed by 3191

“Neurogenic Inflammation: The Participant in Migraine and Recent Advancements in Translational Research”
by Eleonora Spekker, Masaru Tanaka, Agnes Szabo and Laszlo Vecsei
Biomedicines 2022, 10(1), 76; https://doi.org/10.3390/biomedicines10010076
Available online: https://www.mdpi.com/2227-9059/10/1/76
Cited by 41 | Viewed by 8003

“The Neurobiological Correlates of Gaze Perception in Healthy Individuals and Neurologic Patients”
by Simone Battaglia, Jasper H. Fabius, Katarina Moravkova, Alessio Fracasso and Sara Borgomaneri
Biomedicines 2022, 10(3), 627; https://doi.org/10.3390/biomedicines10030627
Available online: https://www.mdpi.com/2227-9059/10/3/627
Cited by 39 | Viewed by 4223

“Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases”
by Carmine Stolfi, Claudia Maresca, Giovanni Monteleone and Federica Laudisi
Biomedicines 2022, 10(2), 289; https://doi.org/10.3390/biomedicines10020289
Available online: https://www.mdpi.com/2227-9059/10/2/289
Cited by 32 | Viewed by 5820

“Role of Microbiota-Gut-Brain Axis in Regulating Dopaminergic Signaling”
by Sevag Hamamah, Armin Aghazarian, Anthony Nazaryan, Andras Hajnal and Mihai Covasa
Biomedicines 2022, 10(2), 436; https://doi.org/10.3390/biomedicines10020436
Available online: https://www.mdpi.com/2227-9059/10/2/436
Cited by 30 | Viewed by 7602

“The Hallmarks of Glioblastoma: Heterogeneity, Intercellular Crosstalk and Molecular Signature of Invasiveness and Progression”
by Filippo Torrisi, Cristiana Alberghina, Simona D’Aprile, Anna M. Pavone, Lucia Longhitano, Sebastiano Giallongo, Daniele Tibullo, Michelino Di Rosa, Agata Zappala, Francesco P. Cammarata et al.
Biomedicines 2022, 10(4), 806; https://doi.org/10.3390/biomedicines10040806
Available online: https://www.mdpi.com/2227-9059/10/4/806
Cited by 28 | Viewed by 3964

“Oxidative Stress in Ischemia/Reperfusion Injuries following Acute Ischemic Stroke”
by Anamaria Jurcau and Adriana Ioana Ardelean
Biomedicines 2022, 10(3), 574; https://doi.org/10.3390/biomedicines10030574
Available online: https://www.mdpi.com/2227-9059/10/3/574
Cited by 27 | Viewed by 3332