We are pleased to invite you to read the 2021 and 2022 selected papers in Cancers (ISSN: 2072-6694) on the topic of clinical trials of cancer. The paper list is as follows:

1. “Comparative Efficacy and Safety of Programmed Death-1 Pathway Inhibitors in Advanced Gastroesophageal Cancers: A Systematic Review and Network Meta-analysis of Phase III Clinical Trials”
by Laercio Lopes da Silva, Pedro Nazareth Aguiar, Jr., Robin Park, Eduardo Edelman Saul, Benjamin Haaland and Gilberto de Lima Lopes
Cancers 2021, 13(11), 2614; https://doi.org/10.3390/cancers13112614
Available online: https://www.mdpi.com/2072-6694/13/11/2614

2. “The Current Landscape of Targeted Clinical Trials in Non-WNT/Non-SHH Medulloblastoma”
by David R. Ghasemi, Gudrun Fleischhack, Till Milde and Kristian W. Pajtler
Cancers 2022, 14(3), 679; https://doi.org/10.3390/cancers14030679
Available online: https://www.mdpi.com/2072-6694/14/3/679

3. “The Clinical and Pathological Profile of BRCA1 Gene Methylated Breast Cancer Women: A Meta-Analysis”
by Ilary Ruscito, Maria Luisa Gasparri, Maria Paola De Marco, Flavia Costanzi, Aris Raad Besharat, Andrea Papadia, Thorsten Kuehn, Oreste Davide Gentilini, Filippo Bellati and Donatella Caserta
Cancers 2021, 13(6), 1391; https://doi.org/10.3390/cancers13061391
Available online: https://www.mdpi.com/2072-6694/13/6/1391

4. “Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia”
by Axel H. Schönthal, Steve Swenson, Radu O. Minea, Hye Na Kim, Heeyeon Cho, Nazleen Mohseni, Yong-Mi Kim and Thomas C. Chen
Cancers 2021, 13(14), 3385; https://doi.org/10.3390/cancers13143385
Available online: https://www.mdpi.com/2072-6694/13/14/3385

5. “Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23”
by Peter Hau, Didier Frappaz, Elizabeth Hovey, Martin G. McCabe, Kristian W. Pajtler, Benedikt Wiestler, Clemens Seidel, Stephanie E. Combs, Linda Dirven, Martin Klein et al.
Cancers 2021, 13(14), 3451; https://doi.org/10.3390/cancers13143451
Available online: https://www.mdpi.com/2072-6694/13/14/3451

6. “Circulating Tumor Cells and Bevacizumab Pharmacokinetics during Neoadjuvant Treatment Combining Chemotherapy and Bevacizumab for Early Breast Cancer: Ancillary Analysis of the AVASTEM Trial”
by Renaud Sabatier, Jean-Yves Pierga, Hervé Curé, Rakan Abulnaja, Eric Lambaudie, François-Clément Bidard, Jean-Marc Extra, Patrick Sfumato and Anthony Gonçalves
Cancers 2021, 13(1), 140; https://doi.org/10.3390/cancers13010140
Available online: https://www.mdpi.com/2072-6694/13/1/140

7. “New Scenarios in Pharmacological Treatments of Head and Neck Squamous Cell Carcinomas”
by Cristina Porcheri and Thimios A. Mitsiadis
Cancers 2021, 13(21), 5515; https://doi.org/10.3390/cancers13215515
Available online: https://www.mdpi.com/2072-6694/13/21/5515

8. “A Phase II Study Demonstrates No Feasibility of Adjuvant Treatment with Six Cycles of S-1 and Oxaliplatin in Resectable Esophageal Adenocarcinoma, with ERCC1 as Biomarker for Response to SOX”
by Charlotte I. Stroes, Sandor Schokker, Remco J. Molenaar, Ron A. A. Mathôt, Maarten F. Bijlsma, Stephanie O. van der Woude, João P. Belo Pereira, Gerrit K. J. Hooijer, Rob H. A. Verhoeven, Annemieke Cats et al.
Cancers 2021, 13(4), 839; https://doi.org/10.3390/cancers13040839
Available online: https://www.mdpi.com/2072-6694/13/4/839

9. “Cardiovascular Toxicities Secondary to Biotherapy and Molecular Targeted Therapies in Neuroendocrine Neoplasms: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials”
by Charalampos Aktypis, Maria-Eleni Spei, Maria Yavropoulou, Göran Wallin, Anna Koumarianou, Gregory Kaltsas, Eva Kassi and Kosmas Daskalakis
Cancers 2021, 13(9), 2159; https://doi.org/10.3390/cancers13092159
Available online: https://www.mdpi.com/2072-6694/13/9/2159

10. “Dramatic Reduction of Distant Pancreatic Metastases Using Local Light Activation of Verteporfin with Nab-Paclitaxel”
by Michael Pigula, Zhiming Mai, Sriram Anbil, Myung-Gyu Choi, Kenneth Wang, Edward Maytin, Brian Pogue and Tayyaba Hasan
Cancers 2021, 13(22), 5781; https://doi.org/10.3390/cancers13225781
Available online: https://www.mdpi.com/2072-6694/13/22/5781

11. “Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells”
by Karolina Łuczkowska, Olga Taryma-Leśniak, Jan Bińkowski, Katarzyna E. Sokołowska, Dominik Strapagiel, Justyna Jarczak, Edyta Paczkowska, Bogusław Machaliński and Tomasz K. Wojdacz
Cancers 2022, 14(14), 3402; https://doi.org/10.3390/cancers14143402
Available online: https://www.mdpi.com/2072-6694/14/14/3402

12. “Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3-ITD+ Acute Myeloid Leukemia”
by Javier Bregante, Anna Schönbichler, Daniel Pölöske, Lina Degenfeld-Schonburg, Garazi Monzó Contreras, Emir Hadzijusufovic, Elvin D. de Araujo, Peter Valent, Richard Moriggl and Anna Orlova
Cancers 2021, 13(24), 6181; https://doi.org/10.3390/cancers13246181
Available online: https://www.mdpi.com/2072-6694/13/24/6181

13. “Oncogene-Induced Reprogramming in Acute Lymphoblastic Leukemia: Towards Targeted Therapy of Leukemia-Initiating Cells”
by Vincent Fregona, Manon Bayet and Bastien Gerby
Cancers 2021, 13(21), 5511; https://doi.org/10.3390/cancers13215511
Available online: https://www.mdpi.com/2072-6694/13/21/5511

14. “Adjuvant Treatment with Tyrosine Kinase Inhibitors in Epidermal Growth Factor Receptor Mutated Non-Small-Cell Lung Carcinoma Patients, Past, Present and Future”
by Walid Shalata, Binil Mathew Jacob and Abed Agbarya
Cancers 2021, 13(16), 4119; https://doi.org/10.3390/cancers13164119
Available online: https://www.mdpi.com/2072-6694/13/16/4119

15. “Molecular Targeted Therapies: Time for a Paradigm Shift in Medulloblastoma Treatment?”
by Lidia Gatto, Enrico Franceschi, Alicia Tosoni, Vincenzo Di Nunno, Stefania Bartolini and Alba Ariela Brandes
Cancers 2022, 14(2), 333; https://doi.org/10.3390/cancers14020333
Available online: https://www.mdpi.com/2072-6694/14/2/333

You can check more information about the Section “Clinical Trials of Cancer” in Cancers at the following link: https://www.mdpi.com/journal/cancers/sections/Clinical_Trials_Cancer.