The “Neuro-oncology” Section of Brain Sciences (ISSN: 2076-3425) aims to publish articles on brain tumors, glioblastoma, low-grade glioma, meningioma, schwannoma, tumor angiogenesis, etc.

As all the articles published in our journal are of an open access format, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2021 and 2022 listed below:

1. “Tumor Microenvironment in Glioma Invasion”
by Sho Tamai, Toshiya Ichinose, Taishi Tsutsui, Shingo Tanaka, Farida Garaeva, Hemragul Sabit and Mitsutoshi Nakada
Brain Sci. 2022, 12(4), 505; https://doi.org/10.3390/brainsci12040505
Available online: https://www.mdpi.com/2076-3425/12/4/505

2. “CT in the Differentiation of Gliomas from Brain Metastases: The Radiomics Analysis of the Peritumoral Zone”
by Lucian Mărginean, Paul Andrei Ștefan, Andrei Lebovici, Iulian Opincariu, Csaba Csutak, Roxana Adelina Lupean, Paul Alexandru Coroian and Bogdan Andrei Suciu
Brain Sci. 2022, 12(1), 109; https://doi.org/10.3390/brainsci12010109
Available online: https://www.mdpi.com/2076-3425/12/1/109

3. “FLAIRectomy: Resecting beyond the Contrast Margin for Glioblastoma”
by Alexander F. Haddad, Jacob S. Young,Ramin A. Morshed and Mitchel S. Berger
Brain Sci. 2022, 12(5), 544; https://doi.org/10.3390/brainsci12050544
Available online: https://www.mdpi.com/2076-3425/12/5/544

4. “The Concept of «Peritumoral Zone» in Diffuse Low-Grade Gliomas: Oncological and Functional Implications for a Connectome-Guided Therapeutic Attitude”
by Melissa Silva, Catalina Vivancos and Hugues Duffau
Brain Sci. 2022, 12(4), 504; https://doi.org/10.3390/brainsci12040504
Available online: https://www.mdpi.com/2076-3425/12/4/504

5. “Fluorescence-Guided Surgery in Glioblastoma: 5-ALA, SF or Both? Differences between Fluorescent Dyes in 99 Consecutive Cases”
by Pietro Zeppa, Raffaele De Marco, Matteo Monticelli, Armando Massara, Andrea Bianconi, Giuseppe Di Perna, Stefania Greco Crasto, Fabio Cofano, Antonio Melcarne, Michele Maria Lanotte et al.
Brain Sci. 2022, 12(5), 555; https://doi.org/10.3390/brainsci12050555
Available online: https://www.mdpi.com/2076-3425/12/5/555

6. “Supramarginal Resection for Glioblastoma: It Is Time to Set Boundaries! A Critical Review on a Hot Topic”
by Francesco Guerrini, Elena Roca and Giannantonio Spena
Brain Sci. 2022, 12(5), 652; https://doi.org/10.3390/brainsci12050652
Available online: https://www.mdpi.com/2076-3425/12/5/652

7. “Evidence of Reelin Signaling in GBM and Its Derived Cancer Stem Cells”
by Filippo Biamonte, Gigliola Sica, Antonio Filippini and Alessio D’Alessio
Brain Sci. 2021, 11(6), 745; https://www.mdpi.com/2076-3425/11/6/745
Available online: https://www.mdpi.com/2076-3425/11/6/745

8. “Oncolytic Virotherapy for Melanoma Brain Metastases, a Potential New Treatment Paradigm?”
by Sauson Soldozy, Kathleen M. Mulligan, David X. Zheng, Melissa A. Levoska, Christopher R. Cullison, Turki Elarjani, Daniel G. Eichberg, Leonel E. Ampie, Ashish H. Shah, Kaan Yağmurlu et al.
Brain Sci. 2021, 11(10), 1260; https://doi.org/10.3390/brainsci11101260
Available online: https://www.mdpi.com/2076-3425/11/10/1260

9. “A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas”
by Yukiko Nakahara, Hiroshi Ito, Hiroki Namikawa, Takashi Furukawa, Fumitaka Yoshioka, Atsushi Ogata, Jun Masuoka and Tatsuya Abe
Brain Sci. 2022, 12(4), 473; https://doi.org/10.3390/brainsci12040473
Available online: https://www.mdpi.com/2076-3425/12/4/473

10. “Infratentorial Stereotactic Biopsy of Brainstem and Cerebellar Lesions”
by Jacek Furtak, Paulina Śledzińska, Marek G. Bebyn, Tadeusz Szylberg, Stanisław Krajewski, Marcin Birski and Marek Harat et al.
Brain Sci. 2021, 11(11), 1432; https://doi.org/10.3390/brainsci11111432
Available online: https://www.mdpi.com/2076-3425/11/11/1432

11. “Immune Landscape in PTEN-Related Glioma Microenvironment: A Bioinformatic Analysis”
by Alice Giotta Lucifero and Sabino Luzzi
Brain Sci. 2022, 12(4), 501; https://doi.org/10.3390/brainsci12040501
Available online: https://www.mdpi.com/2076-3425/12/4/501

12. “Elderly Gliobastoma Patients: The Impact of Surgery and Adjuvant Treatments on Survival: A Single Institution Experience”
by Francesco Bruno, Alessia Pellerino, Edoardo Pronello, Rosa Palmiero, Luca Bertero, Cristina Mantovani, Andrea Bianconi, Antonio Melcarne, Diego Garbossa and Roberta Rudà
Brain Sci. 2022, 12(5), 632; https://doi.org/10.3390/brainsci12050632
Available online: https://www.mdpi.com/2076-3425/12/5/632

13. “Glioma-Associated Microglia Characterization in the Glioblastoma Microenvironment through a ‘Seed-and Soil’ Approach: A Systematic Review”
by Grazia Menna, Pier Paolo Mattogno, Carlo Maria Donzelli, Lucia Lisi, Alessandro Olivi and Giuseppe Maria Della Pepa
Brain Sci. 2022, 12(6), 718; https://doi.org/10.3390/brainsci12060718
Available online: https://www.mdpi.com/2076-3425/12/6/718

14. “Single-Cell RNA Sequencing of Cerebrospinal Fluid as an Advanced Form of Liquid Biopsy for Neurological Disorders”
by Anudeep Yekula, Jovanna Tracz, Jordina Rincon-Torroella, Tej Azad and Chetan Bettegowda
Brain Sci. 2022, 12(7), 812; https://doi.org/10.3390/brainsci12070812
Available online: https://www.mdpi.com/2076-3425/12/7/812

15. “Resting-State Functional Magnetic Resonance Imaging for Surgical Neuro-Oncology Planning: Towards a Standardization in Clinical Settings”
by Gianvincenzo Sparacia, Giuseppe Parla, Giuseppe Mamone, Mariangela Caruso, Fabio Torregrossa and Giovanni Grasso
Brain Sci. 2021, 11(12), 1613; https://doi.org/10.3390/brainsci11121613
Available online: https://www.mdpi.com/2076-3425/11/12/1613

16. “Molecular Mechanisms and Clinical Challenges of Glioma Invasion”
by Tomoya Oishi, Shinichiro Koizumi and Kazuhiko Kurozumi
Brain Sci. 2022, 12(2), 291; https://doi.org/10.3390/brainsci12020291
Available online: https://www.mdpi.com/2076-3425/12/2/291

17. “Relapsing High—Grade Glioma from Peritumoral Zone: Critical Review of Radiotherapy Treatment Options”
by Maria Chiara Lo Greco, Roberto Milazzotto, Rocco Luca Emanuele Liardo, Grazia Acquaviva, Madalina La Rocca, Roberto Altieri, Francesco Certo, Giuseppe Maria Barbagallo, Antonio Basile, Pietro Valerio Foti et al.
Brain Sci. 2022, 12(4), 416; https://doi.org/10.3390/brainsci12040416
Available online: https://www.mdpi.com/2076-3425/12/4/416

18. “Circulating Exosomal-DNA in Glioma Patients: A Quantitative Study and Histopathological Correlations—A Preliminary Study”
by Amedeo Piazza, Paolo Rosa, Luca Ricciardi, Antonella Mangraviti, Luca Pacini, Antonella Calogero, Antonino Raco and Massimo Miscusi
Brain Sci. 2022, 12(4), 500; https://doi.org/10.3390/brainsci12040500
Available online: https://www.mdpi.com/2076-3425/12/4/500

19. “Is Interstitial Chemotherapy with Carmustine (BCNU) Wafers Effective against Local Recurrence of Glioblastoma? A Pharmacokinetic Study by Measurement of BCNU in the Tumor Resection Cavity”
by Takanori Ohnishi, Daisuke Yamashita, Akihiro Inoue, Satoshi Suehiro, Shiro Ohue and Takeharu Kunieda
Brain Sci. 2022, 12(5), 567; https://doi.org/10.3390/brainsci12050567
Available online: https://www.mdpi.com/2076-3425/12/5/567

20. “Brain Tsunamis in Human High-Grade Glioma: Preliminary Observations”
by Kayli Colpitts, Masoom J. Desai, Michael Kogan, C. William Shuttleworth and Andrew P. Carlson
Brain Sci. 2022, 12(6), 710; https://doi.org/10.3390/brainsci12060710
Available online: https://www.mdpi.com/2076-3425/12/6/710