27 December 2023
Cells | Top Cited Papers in 2022 in the Section “Cells of the Nervous System”

“Microglia Phenotypes in Aging and Neurodegenerative Diseases”
by Menbere Y. Wendimu and Shelley B. Hooks
Cells 2022, 11(13), 2091; https://doi.org/10.3390/cells11132091
Available online: https://www.mdpi.com/2073-4409/11/13/2091

“Hydrogen Sulfide Produced by Gut Bacteria May Induce Parkinson’s Disease”
by Kari Erik Murros
Cells 2022, 11(6), 978; https://doi.org/10.3390/cells11060978
Available online: https://www.mdpi.com/2073-4409/11/6/978

“Immunogenic Cell Death, DAMPs and Prothymosin α as a Putative Anticancer Immune Response Biomarker”
by Anastasios I. Birmpilis, Antonios Paschalis, Apostolis Mourkakis, Panayiota Christodoulou, Ioannis V. Kostopoulos, Elina Antimissari, Georgia Terzoudi, Alexandros G. Georgakilas, Christina Armpilia, Panagiotis Papageorgis et al.
Cells 2022, 11(9), 1415; https://doi.org/10.3390/cells11091415
Available online: https://www.mdpi.com/2073-4409/11/9/1415

“Role of Microglia and Astrocytes in Alzheimer’s Disease: From Neuroinflammation to Ca2+ Homeostasis Dysregulation”
by Giulia Di Benedetto, Chiara Burgaletto, Carlo Maria Bellanca, Antonio Munafò, Renato Bernardini and Giuseppina Cantarella
Cells 2022, 11(17), 2728; https://doi.org/10.3390/cells11172728
Available online: https://www.mdpi.com/2073-4409/11/17/2728

“Mitochondrial Neurodegeneration”
by Massimo Zeviani and Carlo Viscomi
Cells 2022, 11(4), 637; https://doi.org/10.3390/cells11040637
Available online: https://www.mdpi.com/2073-4409/11/4/637

“New Insights into Neuroinflammation Involved in Pathogenic Mechanism of Alzheimer’s Disease and Its Potential for Therapeutic Intervention”
by Tiantian Li, Li Lu, Eloise Pember, Xinuo Li, Bocheng Zhang and Zheying Zhu
Cells 2022, 11(12), 1925; https://doi.org/10.3390/cells11121925
Available online: https://www.mdpi.com/2073-4409/11/12/1925

“The Role of Microglia in Neuroinflammation of the Spinal Cord after Peripheral Nerve Injury”
by Tana S. Pottorf, Travis M. Rotterman, William M. McCallum, Zoë A. Haley-Johnson and Francisco J. Alvarez
Cells 2022, 11(13), 2083; https://doi.org/10.3390/cells11132083
Available online: https://www.mdpi.com/2073-4409/11/13/2083

“Effect of Ultra-Micronized Palmitoylethanolamide and Luteolin on Olfaction and Memory in Patients with Long COVID: Results of a Longitudinal Study”
by Pietro De Luca, Angelo Camaioni, Pasquale Marra, Giovanni Salzano, Giovanni Carriere, Luca Ricciardi, Resi Pucci, Nicola Montemurro, Michael J. Brenner and Arianna Di Stadio
Cells 2022, 11(16), 2552; https://doi.org/10.3390/cells11162552
Available online: https://www.mdpi.com/2073-4409/11/16/2552

“The Influence of Gut Microbiota on Neurogenesis: Evidence and Hopes”
by Fiorella Sarubbo, Virve Cavallucci and Giovambattista Pani
Cells 2022, 11(3), 382; https://doi.org/10.3390/cells11030382
Available online: https://www.mdpi.com/2073-4409/11/3/382

“Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway Modulators, from Current Insights to Future Perspectives”
by Gary Álvarez Bravo, René Robles Cedeño, Marc Puig Casadevall and Lluís Ramió-Torrentà
Cells 2022, 11(13), 2058; https://doi.org/10.3390/cells11132058
Available online: https://www.mdpi.com/2073-4409/11/13/2058

“Gene Therapy in Amyotrophic Lateral Sclerosis”
by Ton, Goun Je Fang, Peter Pacut, Kiandokht Keyhanian, Jeff Gao and Mehdi Ghasemi
Cells 2022, 11(13), 2066; https://doi.org/10.3390/cells11132066
Available online: https://www.mdpi.com/2073-4409/11/13/2066

“Pharmacotherapy Evolution in Alzheimer’s Disease: Current Framework and Relevant Directions”
by Denisa Claudia Miculas, Paul Andrei Negru, Simona Gabriela Bungau, Tapan Behl, Syed Shams ul Hassan and Delia Mirela Tit
Cells 2023, 12(1), 131; https://doi.org/10.3390/cells12010131
Available online: https://www.mdpi.com/2073-4409/12/1/131

“Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition”
by Alessandro Papa, Silvia Pasquini, Chiara Contri, Sandra Gemma, Giuseppe Campiani, Stefania Butini, Katia Varani and Fabrizio Vincenzi
Cells 2022, 11(3), 471; https://doi.org/10.3390/cells11030471
Available online: https://www.mdpi.com/2073-4409/11/3/471

“Adult Neurogenesis under Control of the Circadian System”
by Amira A. H. Ali and Charlotte von Gall
Cells 2022, 11(5), 764; https://doi.org/10.3390/cells11050764
Available online: https://www.mdpi.com/2073-4409/11/5/764

“MicroRNA Networks in Cognition and Dementia”
by Grace S. Blount, Layton Coursey and Jannet Kocerha
Cells 2022, 11(12), 1882; https://doi.org/10.3390/cells11121882
Available online: https://www.mdpi.com/2073-4409/11/12/1882

“Glatiramer Acetate Immunomodulation: Evidence of Neuroprotection and Cognitive Preservation”
by Arielle Kasindi, Dieu-Trang Fuchs, Yosef Koronyo, Altan Rentsendorj, Keith L. Black and Maya Koronyo-Hamaoui
Cells 2022, 11(9), 1578; https://doi.org/10.3390/cells11091578
Available online: https://www.mdpi.com/2073-4409/11/9/1578

“Neuro-Axonal Damage and Alteration of Blood–Brain Barrier Integrity in COVID-19 Patients”
by Maria Antonella Zingaropoli, Marco Iannetta, Lorenzo Piermatteo, Patrizia Pasculli, Tiziana Latronico, Laura Mazzuti, Laura Campogiani, Leonardo Duca, Giampiero Ferraguti, Manuela De Michele et al.
Cells 2022, 11(16), 2480; https://doi.org/10.3390/cells11162480
Available online: https://www.mdpi.com/2073-4409/11/16/2480

“Molecular Mechanisms in Pentanucleotide Repeat Diseases”
by Joana R. Loureiro, Ana F. Castro, Ana S. Figueiredo and Isabel Silveira
Cells 2022, 11(2), 205; https://doi.org/10.3390/cells11020205
Available online: https://www.mdpi.com/2073-4409/11/2/205

“LEAP-2 Counteracts Ghrelin-Induced Food Intake in a Nutrient, Growth Hormone and Age Independent Manner”
by Javier Lugilde, Sabela Casado, Daniel Beiroa, Juan Cuñarro, Montserrat Garcia-Lavandeira, Clara V. Álvarez, Rubén Nogueiras, Carlos Diéguez and Sulay Tovar
Cells 2022, 11(3), 324; https://doi.org/10.3390/cells11030324
Available online: https://www.mdpi.com/2073-4409/11/3/324

“Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients”
by Riikka Lampinen, Mohammad Feroze Fazaludeen, Simone Avesani, Tiit Örd, Elina Penttilä, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Liudmila Saveleva, Emma Kaartinen et al.
Cells 2022, 11(4), 676; https://doi.org/10.3390/cells11040676
Available online: https://www.mdpi.com/2073-4409/11/4/676

“L-Thyroxine Improves Vestibular Compensation in a Rat Model of Acute Peripheral Vestibulopathy: Cellular and Behavioral Aspects”
by Guillaume Rastoldo, Emna Marouane, Nada El-Mahmoudi, David Péricat, Isabelle Watabe, Agnes Lapotre, Alain Tonetto, Alejandra López-Juárez, Abdessadek El-Ahmadi, Philippe Caron et al.
Cells 2022, 11(4), 684; https://doi.org/10.3390/cells11040684
Available online: https://www.mdpi.com/2073-4409/11/4/684

“Antagonism of CGRP Receptor: Central and Peripheral Mechanisms and Mediators in an Animal Model of Chronic Migraine”
by Rosaria Greco, Chiara Demartini, Miriam Francavilla, Anna Maria Zanaboni and Cristina Tassorelli
Cells 2022, 11(19), 3092; https://doi.org/10.3390/cells11193092
Available online: https://www.mdpi.com/2073-4409/11/19/3092

“Levodopa-Induced Dyskinesia in Parkinson’s Disease: Pathogenesis and Emerging Treatment Strategies”
by Destany K. Kwon, Mohit Kwatra, Jing Wang and Han Seok Ko
Cells 2022, 11(23), 3736; https://doi.org/10.3390/cells11233736
Available online: https://www.mdpi.com/2073-4409/11/23/3736

“Fibrotic Scar in CNS Injuries: From the Cellular Origins of Fibroblasts to the Molecular Processes of Fibrotic Scar Formation”
by Maryam Ayazi, Sandra Zivkovic, Grace Hammel, Branko Stefanovic and Yi Ren
Cells 2022, 11(15), 2371; https://doi.org/10.3390/cells11152371
Available online: https://www.mdpi.com/2073-4409/11/15/2371

“ATP-Sensitive Potassium Channels in Migraine: Translational Findings and Therapeutic Potential”
by Amalie Clement, Song Guo, Inger Jansen-Olesen and Sarah Louise Christensen
Cells 2022, 11(15), 2406; https://doi.org/10.3390/cells11152406
Available online: https://www.mdpi.com/2073-4409/11/15/2406

“Increased Numbers of Enteric Glial Cells in the Peyer’s Patches and Enhanced Intestinal Permeability by Glial Cell Mediators in Patients with Ileal Crohn’s Disease”
by Olga Biskou, Felipe Meira de-Faria, Susanna M. Walter, Martin E. Winberg, Staffan Haapaniemi, Pär Myrelid, Johan D. Söderholm and Åsa V. Keita
Cells 2022, 11(3), 335; https://doi.org/10.3390/cells11030335
Available online: https://www.mdpi.com/2073-4409/11/3/335

“Physiological Function during Exercise and Environmental Stress in Humans—An Integrative View of Body Systems and Homeostasis”
by Gavin Travers, Pascale Kippelen, Steven J. Trangmar and José González-Alonso
Cells 2022, 11(3), 383; https://doi.org/10.3390/cells11030383
Available online: https://www.mdpi.com/2073-4409/11/3/383

“Early Cellular, Molecular, Morphological and Behavioral Changes in the Humanized Amyloid-Beta-Knock-In Mouse Model of Late-Onset Alzheimer’s Disease”
by Sudhir Kshirsagar, Rainier Vladlen Alvir, Ashly Hindle, Subodh Kumar, Murali Vijayan, Jangampalli Adi Pradeepkiran, Arubala P. Reddy, Bhagavathi Ramasubramanian and P. Hemachandra Reddy
Cells 2022, 11(4), 733; https://doi.org/10.3390/cells11040733
Available online: https://www.mdpi.com/2073-4409/11/4/733

“LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss”
by Dong-Hwan Ho, Daleum Nam, Mikyoung Seo, Sung-Woo Park, Wongi Seol and Ilhong Son
Cells 2022, 11(5), 861; https://doi.org/10.3390/cells11050861
Available online: https://www.mdpi.com/2073-4409/11/5/861

“Medicinal Herbs in the Relief of Neurological, Cardiovascular and Respiratory Symptoms after COVID-19 Infection A Literature Review”
by Joanna Nawrot, Justyna Gornowicz-Porowska, Jaromir Budzianowski, Gerard Nowak, Grzegorz Schroeder and Joanna Kurczewska
Cells 2022, 11(12), 1897; https://doi.org/10.3390/cells11121897
Available online: https://www.mdpi.com/2073-4409/11/12/1897

“MiRNAs as Promising Translational Strategies for Neuronal Repair and Regeneration in Spinal Cord Injury”
by Serena Silvestro and Emanuela Mazzon
Cells 2022, 11(14), 2177; https://doi.org/10.3390/cells11142177
Available online: https://www.mdpi.com/2073-4409/11/14/2177

“Current Understanding of the Neural Stem Cell Niches”
by Vicente Llorente, Pedro Velarde, Manuel Desco and María Victoria Gómez-Gaviro
Cells 2022, 11(19), 3002; https://doi.org/10.3390/cells11193002
Available online: https://www.mdpi.com/2073-4409/11/19/3002

“Endosomal Recycling Defects and Neurodevelopmental Disorders”
by Shinji Saitoh
Cells 2022, 11(1), 148; https://doi.org/10.3390/cells11010148
Available online: https://www.mdpi.com/2073-4409/11/1/148

“How Is Peripheral Injury Signaled to Satellite Glial Cells in Sensory Ganglia?”
by Menachem Hanani
Cells 2022, 11(3), 512; https://doi.org/10.3390/cells11030512
Available online: https://www.mdpi.com/2073-4409/11/3/512

“Dual Effects of Korean Red Ginseng on Astrocytes and Neural Stem Cells in Traumatic Brain Injury: The HO-1–Tom20 Axis as a Putative Target for Mitochondrial Function”
by Minsu Kim, Sunhong Moon, Hui Su Jeon, Sueun Kim, Seong-Ho Koh, Mi-Sook Chang, Young-Myeong Kim and Yoon Kyung Choi
Cells 2022, 11(5), 892; https://doi.org/10.3390/cells11050892
Available online: https://www.mdpi.com/2073-4409/11/5/892

“Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis”
by Bidisha Paul, Zachary R. Sterner, Daniel R. Buchholz, Yun-Bo Shi and Laurent M. Sachs
Cells 2022, 11(10), 1595; https://doi.org/10.3390/cells11101595
Available online: https://www.mdpi.com/2073-4409/11/10/1595

“Different Methods for Evaluating Microglial Activation Using Anti-Ionized Calcium-Binding Adaptor Protein-1 Immunohistochemistry in the Cuprizone Model”
by Mariela Wittekindt, Hannes Kaddatz, Sarah Joost, Anna Staffeld, Yamen Bitar, Markus Kipp and Linda Frintrop
Cells 2022, 11(11), 1723; https://doi.org/10.3390/cells11111723
Available online: https://www.mdpi.com/2073-4409/11/11/1723

“The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow”
by Mária Dux, Birgit Vogler, Annette Kuhn, Kimberly D. Mackenzie, Jennifer Stratton and Karl Messlinger
Cells 2022, 11(11), 1768; https://doi.org/10.3390/cells11111768
Available online: https://www.mdpi.com/2073-4409/11/11/1768

“Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease”
by Mehmet Ilyas Cosacak, Prabesh Bhattarai, Philip L. De Jager, Vilas Menon, Giuseppe Tosto and Caghan Kizil
Cells 2022, 11(11), 1807; https://doi.org/10.3390/cells11111807
Available online: https://www.mdpi.com/2073-4409/11/11/1807

“Targeting the Subventricular Zone to Promote Myelin Repair in the Aging Brain”
by Arthur Morgan Butt, Andrea Dominico Rivera, Daniel Fulton and Kasum Azim
Cells 2022, 11(11), 1809; https://doi.org/10.3390/cells11111809
Available online: https://www.mdpi.com/2073-4409/11/11/1809

“Pathophysiology and Therapy of Associated Features of Migraine”
by Maria Dolores Villar-Martinez and Peter J. Goadsby
Cells 2022, 11(17), 2767; https://doi.org/10.3390/cells11172767
Available online: https://www.mdpi.com/2073-4409/11/17/2767

“Remodeling of the Neurovascular Unit Following Cerebral Ischemia and Hemorrhage”
by Yoshimichi Sato, Jaime Falcone-Juengert, Teiji Tominaga, Hua Su and Jialing Liu
Cells 2022, 11(18), 2823; https://doi.org/10.3390/cells11182823
Available online: https://www.mdpi.com/2073-4409/11/18/2823

“Branched-Chain Amino Acids Are Linked with Alzheimer’s Disease-Related Pathology and Cognitive Deficits”
by Md Abu Bakkar Siddik, Caitlyn A. Mullins, Alyssa Kramer, Harsh Shah, Ritchel B. Gannaban, Masoud Zabet-Moghaddam, Ryan M. Huebinger, Vijay K. Hegde, Sheba M. J. MohanKumar, Puliyur S. MohanKumar et al.
Cells 2022, 11(21), 3523; https://doi.org/10.3390/cells11213523
Available online: https://www.mdpi.com/2073-4409/11/21/3523

“Monoclonal Antibodies against Calcitonin Gene-Related Peptide for Migraine Prophylaxis: A Systematic Review of Real-World Data”
by Antun R. Pavelic, Christian Wöber, Franz Riederer and Karin Zebenholzer
Cells 2023, 12(1), 143; https://doi.org/10.3390/cells12010143
Available online: https://www.mdpi.com/2073-4409/12/1/143

“What’s in a Gene? The Outstanding Diversity of MAPT
by Daniel Ruiz-Gabarre, Almudena Carnero-Espejo, Jesús Ávila and Vega García-Escudero
Cells 2022, 11(5), 840; https://doi.org/10.3390/cells11050840
Available online: https://www.mdpi.com/2073-4409/11/5/840

“The Physiological Roles of the Exon Junction Complex in Development and Diseases”
by Shravan Asthana, Hannah Martin, Julian Rupkey, Shray Patel, Joy Yoon, Abiageal Keegan and Yingwei Mao
Cells 2022, 11(7), 1192; https://doi.org/10.3390/cells11071192
Available online: https://www.mdpi.com/2073-4409/11/7/1192

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