**Jae Hoon Chung <sup>1</sup> and Sehoon Jeong 2,3,4,\***


Received: 26 October 2020; Accepted: 21 November 2020; Published: 27 November 2020

**Abstract:** At the International Space Station (ISS), not only observation of the space environment, but also biological and medical research under weightlessness has been conducted. The efficient use of energy from waste heat from the ISS away from the Earth is very important to the efficient operation of the ISS. To develop a thermoelectric module that can be used for real-time polymerase chain reaction (PCR) machinery used in biological and medical research, we simulated and evaluated the thermoelectric waste heat recovery system. Specifically, the thermoelectric module was attached to a stainless steel duct, and a hot air blower was faced with the duct inlet. The power of the thermoelectric system was measured by controlling the temperature of the hot air inlet. Additionally, the thermoelectric performance was evaluated according to the heat sink attached to the cold side of the thermoelectric module. Here, we also found the optimal heat exchange factors to improve the power and efficiency of the thermoelectric module. In this regard, it is expected that the thermoelectric module development and analysis study using waste heat will play an important role in the biological and medical research that is being conducted at ISS by developing a real-time PCR utilizing it.

**Keywords:** thermoelectric system; waste heat recovery; real-time polymerase chain reaction
